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Tomographic Reconstruction of the Small-Angle X-Ray Scattering Tensor with Filtered Back Projection

Small-angle x-ray scattering tensor tomography provides three-dimensional information on the unresolved material anisotropic microarchitecture, which can be hundreds of times smaller than an image pixel. We develop a direct filtered back-projection method based on algebraic filters that enables rapid tensor-tomographic reconstructions and is a few orders of magnitude faster compared to established

Envelope modulated x-ray grating interferometry

X-ray dark-field and phase contrast imaging using grating interferometry (GI) have demonstrated great potential for medical and industrial applications. GI relies on the fabrication of high-quality absorption gratings, which has revealed to be quite challenging. This paper proposes an interferometer for dark-field and differential phase contrast imaging using a single phase-shifting element. This

Macroscopic mapping of microscale fibers in freeform injection molded fiber-reinforced composites using X-ray scattering tensor tomography

Fiber-reinforced composites deliver lightweight but strong structures that are crucial in applications ranging from aerospace to the automotive industry. The advent of freeform injection molding has made the manufacturing of complex fiber-reinforced composites with full design freedom possible. Prediction of the mechanical properties, dictated by the local microfiber orientation, is essential for

Vertical III-V nanowire tunnel field-effect transistors : a circuit perspective

The energy scaling of integrated circuits has reached its limit because the operating voltage of Metal-Oxide-Semiconductor Field-Effect Transistors (MOSFET) based switches has reached its minimum value. MOSFETs are limited by thermionic emission and cannot achieve a subthreshold swing (SS) below 60 mV/decade at room temperature. Tunnel Field-Effect Transistors (TFET), which operate on field modula

Needs, barriers and facilitators for a healthier lifestyle in haemodialysis patients : The GoodRENal project

Background: Malnutrition, sedentary lifestyle, cognitive dysfunction and poor psychological well-being are often reported in patients on haemodialysis (HD). Aims: We aimed to explore needs, barriers and facilitators—as perceived by patients, their carers, and healthcare professionals (HCPs) for increasing the adherence to the diet, to physical activity and cognition and psychological well-being. M

Path Planning Using Wasserstein Distributionally Robust Deep Q-learning

We investigate the problem of risk averse robot path planning using the deep reinforcement learning and distributionally robust optimization perspectives. Our problem formulation involves modelling the robot as a stochastic linear dynamical system, assuming that a collection of process noise samples is available. We cast the risk averse motion planning problem as a Markov decision process and prop

Moving Target Detection Using a Distributed MIMO Radar System With Synchronization Errors

This article addresses the detection and estimation problems of a distributed multiple-input and multiple-output (MIMO) radar system with synchronization errors. In such cases, the outputs of all waveform-specific matched filters contain errors in the resulting time delay estimates, which will cause biases in the corresponding estimation of the active range cells. To overcome the impact resulting

Professional Activism : AIDS and Civil Society in Sweden, 1982–2000

The Swedish HIV/AIDS epidemic accelerated the hybridisation of welfare, as volunteer organisations rapidly professionalised and expanded their welfare services. The media’s horror scenarios prompted a sense of urgency which, in turn, motivated politicians and state funding agencies to channel large amounts of money into Swedish volunteer organisations. These included RFSL (the National Union for S

Emergency department crowding and mortality : an observational multicenter study in Sweden

Background: Emergency department (ED) crowding is a serious problem worldwide causing decreased quality of care. It is reasonable to assume that the negative effects of crowding are at least partially due to high staff workload, but previous crowding metrics based on high workload have not been generalisable to Swedish EDs and have not been associated with increased mortality, in contrast to, e.g.

Novel precision medicine approaches and treatment strategies in hematological malignancies

Genetic testing has been applied for decades in clinical routine diagnostics of hematological malignancies to improve disease (sub)classification, prognostication, patient management, and survival. In recent classifications of hematological malignancies, disease subtypes are defined by key recurrent genetic alterations detected by conventional methods (i.e., cytogenetics, fluorescence in situ hybr

Cyclosporine as Therapy for Traumatic Brain Injury

Drug development in traumatic brain injury (TBI) has been impeded by the complexity and heterogeneity of the disease pathology, as well as limited understanding of the secondary injury cascade that follows the initial trauma. As a result, patients with TBI have an unmet need for effective pharmacological therapies. One promising drug candidate is cyclosporine, a polypeptide traditionally used to a

Probability of independent walking and wheeled mobility in individuals with cerebral palsy

Aim: To estimate the probability of independent walking and wheeled mobility in individuals with cerebral palsy (CP) at home and in the community in relation to age and gross motor function. Method: This was a longitudinal cohort study using data reported into the combined Swedish CP follow-up programme and national quality registry from October 2000 to October 2022. Walking, walking with aids, wh

Designing Optimal Frequency Offsets for Frequency Diverse Array MIMO Radar

Frequency diverse array (FDA) radars provide a potential solution to target localisation along the slant range and azimuth angle due to the range-angle-dependent transmit beampattern caused by the used frequency increments. However, the S -shaped beampattern resulting from the standard FDA leads to multiple candidate location estimates, introducing ambiguity in the target localization. To make ful

Biosphere Defenders Leveraging the Human Right to Healthy Environment for Transformative Change

Earth's life support systems depend on biodiversity and healthy ecosystems. Without radical transformations, staying within safe planetary boundaries becomes impossible. While the inequalities between Global North and Global South are increasingly acknowledged, the agency and rights of people often placed in the category of 'vulnerable' -women, youth, indigenous peoples and local communities- are