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Advanced glyeation end products (AGEs) are thought to play a major pathogenic role in diabetic retinopathy. The most important AGE is unknown, but as increased serum methylglyoxal-derived hydroimidazolone has been demonstrated in patients with type 2 diabetes mellitus, the aim of the present study was to elucidate possible associations between serum levels of hydroimidazolone and retinopathy in pa

The Rhodobacter capsulatus BchI protein is one of three subunits of Mg chelatase, the enzyme which catalyzes the first committed step of chlorophyll and bacteriochlorophyll biosynthesis. The BchI protein was produced with an inducible T7 RNA polymerase expression system in Escherichia coli. The protein was purified from the soluble cell-extract fraction and crystallized from polyethylene glycol so

Impaired appetite and weight changes are commonly seen in patients with depression, but the pathophysiology behind this imbalance between energy intake and energy expenditure remains largely unknown. The aim of this paper is to review the literature regarding a possible role for cytokines in the regulation of appetite and body weight, with special emphasis on depression. There now exists a substan

This is a study of the second century AD literary work 'Periegesis Hellados', i.e. description of, or guide to, Greece, written by the otherwise unknown author Pausanias. This is a purely textual study with the whole of the Periegesis as its object. It falls into two parts. In part one we study the frame narrative. The current views on the 'theoremata' and 'logoi' in the Periegesis is reconsidere

Case study is an important research methodology for software engineering. We have identified the need for checklists supporting researchers and reviewers in conducting and reviewing case studies. We derived checklists for researchers and reviewers respectively, using systematic qualitative procedures. Based on nine sources on case studies, checklists are derived and validated, and hereby presented

Purpose: Desmopressin is a well established and effective therapy for nocturnal enuresis. Water intoxication leading to hyponatremia is an infrequent but serious adverse event associated with desmopressin. We assessed the safety of desmopressin in children 18 years or younger with nocturnal enuresis with a focus on the relative safety of the oral compared with the intranasal formulation. Materials

Introduction: Impacted morselized bone allograft is thought to be remodeled to a great extent. We have previously shown that load-bearing increases the remodeling of impacted morselized bone allografts in a rabbit knee prosthesis model. Bone Morphogenic Proteins (BMPs) also stimulate bone formation and bone allograft remodeling. In this study, our aim was to determine whether it was possible to in

I denna artikel har jag försökt visa att när man engagerar sig i en politisk rörelse spelar emotioner en inte obetydlig roll. Ty den fråga man måste ställa sig är om det är troligt att känslorna inte har någon betydelse för de personer som är aktiva i föreningar av olika slag? Tron att passion och emotioner har en betydelse för engagemanget kan ses som ett alternativ till uppfattning att det är ”i

Some raw material characteristics were evaluated in three apple varieties cultivated in Southern Sweden, namely Kim, Mutsu and Jonagold. The study was undertaken to collect information in order to identify the effects of initial tissue properties on mass transport phenomena in general, and osmotic processing responses in particular. The texture profile analysis revealed cortex anisotropy of the th

The Swedish function word 'att' tends to be phonetically marked in hesitation contexts. The relation between such contexts and the syntactic complexity of the following clause is discussed.

Arbetarförfattare skriver deckare och når en bred publik. Men man kan lika väl säga att de förvandlar sig till underhållningsförfattare. Kanske går de under för en borgerlig kultur på samma sätt som när modernismen blev viktigare än klassen i litteraturen i mitten av förra seklet. Vänstern måste bygga upp sina egna kulturella institutioner om dagens arbetarlitteratur ska vidareutvecklas. Magnus Ni

This article outlines experimental and numerical studies on shrinkage of High-Performance Concrete, HPC. Especially carbonation shrinkage may introduce surface cracking in concrete, which affects the durability. In order to study shrinkage, cylinders of eight qualities of HPC were investigated. Parallel studies on autogenous shrinkage, drying shrinkage, hydration, internal relative humidity and st

Positron annihilation spectroscopy can be used to determine the role of vacancy defects in semiconductors, by identification and quantification of the vacancies and their chemical surroundings. We have studied 0.5-0.8 mum thick low temperature MBE GaMnAs layers with Mn content 0.5-5% and different As-2 partial pressures at growth. The Doppler broadening results show that the Ga vacancy concentrati

Neurons have been neglected as cells with major immune regulatory function. Here, we present novel data demonstrating that neurons are highly immune competent and play crucial role in regulation of T cell response and CNS inflammation. Neurons induce proliferation of activated CD4+T cells via B7-CD28 and TGF-?1-TGF-?R signaling pathways with amplification of TCR signaling and increased phosphoryla