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Association between symptomatic remission and functional outcome in first-episode schizophrenia

Although operational criteria for remission in schizophrenia have recently been proposed, the association of this definition with broader functional outcome has not yet been established in first-episode patients. The severity criteria for remission consist of a score of mild or less on eight core symptoms of schizophrenia. We applied the severity criteria for remission to a sample of patients with

Specialist Contractors' Approach to Quality Management in Sweden

The term 'specialist contractor' in Sweden refers to all contractors who are involved in the construction process, apart from the general contractor. About 12 organizations from eight groups or trades were selected for interviews and the results of those interested and complying with ISO 9000 was varied with the most common problems for the specialist contractors easily identified.

A dry ligand-binding cavity in a solvated protein

Ligands usually bind to proteins by displacing water from the binding site. The affinity and kinetics of binding therefore depend on the hydration characteristics of the site. Here, we show that the extreme case of a completely dehydrated free binding site is realized for the large nonpolar binding cavity in bovine beta-lactoglobulin. Because spatially delocalized water molecules may escape detect

Hemhjälp i Norden: Är omsorg möjlig under vilka villkor som helst?

Denna artikel, som fokuserar hemhjälp till gamla, uppmärksammar dels omsorgens skiftande uttryck i avlönat arbete, dels den hotbild mot omsorgens förutsättningar som kunde skönjas i organisationsmodeller som började införas redan för ett par decennier sedan. Artikeln baserar sig i huvudsak på ett projekt som dokumenteras i antologin Hemhjälp i Norden (red Marta Szebehely, 2003).

Comparison of different frequency controllers for a VSC-HVDC supplied system

This paper studies three different frequency controllers and their effects on the voltage disturbance ride-through capability of a VSC-HVDC supplied industrial system. The idea of implementing frequency controller is to improve the power quality of industrial plants by slightly decreasing the VSC output voltage frequency since industrial processes are more sensitive to voltage drops than frequency

Development and validation of a brief, descriptive Danish pain questionnaire (BDDPQ)

BACKGROUND: A new pain questionnaire should be simple, be documented to have discriminative function, and be related to previously used questionnaires. METHODS: Word meaning was validated by using bilingual Danish medical students and asking them to translate words taken from the Danish version of the McGill pain questionnaire into English. Evaluative word value was estimated using a visual analog

Apnea and bradypnea in patients receiving epidural bupivacaine-morphine for postoperative pain relief as assessed by a new monitoring method.

STUDY OBJECTIVE: To evaluate postoperative breathing patterns with a new monitoring device in patients given bupivacaine-morphine epidural analgesia. DESIGN: Open explorative study. SETTING: Inpatient anesthesia in a university hospital setting. PATIENTS: 15 ASA physical status I and II patients aged 28 to 87 years and scheduled for major abdominal surgery. INTERVENTIONS: All patients underwent ab

Body size and breast cancer risk: Findings from the european prospective investigation into cancer and nutrition (EPIC)

The evidence for anthropometric factors influencing breast cancer risk is accumulating, but uncertainties remain concerning the role of fat distribution and potential effect modifiers. We used data from 73,542 premenopausal and 103,344 postmenopausal women from 9 European countries, taking part in the EPIC study. RRs from Cox regression models were calculated, using measured height, weight, BMI an

Surface enhanced Raman scattering of pyridine adsorbed on Au@Pd core/shell nanoparticles

Surface enhanced Raman scattering (SERS) of pyridine adsorbed on Au@Pd core/shell nanoparticles has been investigated theoretically with quantum chemical method, generalized Mie theory and three-dimensional finite-difference time domain (3D-FDTD) method. We first studied the influence of the coated Pd on the electronic structure of Au nanoparticle, and compared the electronic structure of Au-20 cl

Alcohol, tobacco and breast cancer - collaborative reanalysis of individual data from 53 epidemiological studies, including 58515 women with breast cancer and 95067 women without the disease

Alcohol and tobacco consumption are closely correlated and published results on their association with breast cancer have not always allowed adequately for confounding between these exposures. Over 80% of the relevant information worldwide on alcohol and tobacco consumption and breast cancer were collated, checked and analysed centrally. Analyses included 58515 women with invasive breast cancer an

The evolution of European guidelines: Changing the management of cholesterol levels.

Cardiovascular disease (CVD) is the leading cause of death in Europe and the US. This paper reviews the evolution of the Joint European Societies' guidelines with respect to their lipid recommendations. We stress the importance of lowering lipid levels to, or below, the currently recommended goals and argue that patients' global risk for CVD, rather than baseline lipid levels, should direct the in

Flux and energy requirement during ultrafiltration of a complex industrial process stream

Membrane filtration is a separation process already used in many industrial applications. However, optimization of the design and operating conditions is necessary to lower the investment and operating costs. To achieve this for industrial (multi-component) process streams, a combination of experiments and calculations is needed. The permeate flux and energy requirement are important design parame

Spatially resolved, single-ended two-dimensional visualization of gas flow phenomena using structured illumination

A method for 3D mapping of scattering particle concentration in a gaseous medium based on the back-scattered light in a single direction has been demonstrated. The technique is originally developed for microscopy but now implemented on larger-scale samples. The technique used is known as structured illumination, where a sinusoidal grid pattern is projected onto the medium, thus marking the in-focu

Standing guard - being a relative to a hospitalised, elderly person

Caregiving relatives continue to feel primarily responsible for the care and well-being of elderly persons, when they are admitted to hospital. Although involvement of relatives in decision-making is rare, and the hospitalisation therefore may be a frustrating experience, little is known of relatives, experience of the hospitalisation of elderly persons from a life-world perspective. In this pheno

Demand and supply factors in the fertility transition: a county-level analysis of age-specific marital fertility in Sweden, 1880-1930

This article studies the importance of demand and supply factors in the Swedish fertility transition using county-level data and panel regressions. Fertility started to decline around 1880 when marital fertility began a continuous decline. A gradual diffusion of parity-specific control was important in this process. The fertility of the oldest age groups declined fastest, even though the decline s

Prediction of Alzheimer's Disease Using the CSF Abeta42/Abeta40 Ratio in Patients with Mild Cognitive Impairment.

Evidence supports an important role for beta-amyloid (A beta) in the pathogenesis of Alzheimer's disease ( AD). Here, we investigate baseline levels of the 40- and 42-amino-acid-long A beta peptides (A beta 40 and A beta 42) in cerebrospinal fluid (CSF) from a cohort of patients with mild cognitive impairment (MCI, n = 137) in relation to the final diagnosis after 4 - 6 years of follow-up time. CS

New pulsating white dwarfs in cataclysmic variables

The number of discovered non-radially pulsating white dwarfs (WDs) in cataclysmic variables (CVs) is increasing rapidly by the aid of the Sloan Digital Sky Survey (SDSS). We performed photometric observations of two additional objects, SDSS J133941.11+484727.5 (SDSS 1339), independently discovered as a pulsator by Gansicke et al., and SDSS J151413.72+454911.9, which we identified as a CV/ZZ Ceti h

The effect of protamine sulphate on plasma tissue factor pathway inhibitor released by intravenous and subcutaneous unfractionated and low molecular weight heparin in man

Heparin, a negatively charged sulphated glycosaminoglycan, is clinically the most important antithrombotic drug. Heparin augments the inhibitory activity of antithrombin (AT) towards thrombin, factor Xa (FXa) and other activated clotting enzymes. Tissue factor pathway inhibitor (TFPI) is an endogenous heparin releasable three domain Kunitz-type coagulation inhibitor which inhibits the crucial tiss