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Immunological dependence of plant-dwelling animals on the medicinal properties of their plant substrates: a preliminary test of a novel evolutionary hypothesis

We present preliminary evidence for a novel evolutionary hypothesis, i.e., that animals living on plants high in antimicrobial secondary metabolites could, via drift or selection, evolve weakened immune defenses and an immunological dependence on the antimicrobial properties of their plant substrate and/or the volatile mix in the air surrounding their plant. Animals experience immunological stress

Construct Validity of a New Rating Scale for Self-Reported Impairments in Persons With Late Effects of Polio.

OBJECTIVE: To evaluate the construct validity of a new rating scale for self-reported impairments in persons with late effects of polio. DESIGN: Psychometric analysis of data on self-perceived impairments in persons with prior polio. PARTICIPANTS: Two hundred and seventy-three persons with prior polio (119 men and 154 women; mean age, 63.5 years). METHOD: Rasch analysis of a 13-item rating scale w

Efficient Purification of CD4+ Lymphocytes from Peripheral Blood Progenitor Cell Products Using Affinity Bead Acoustophoresis

Processing of peripheral blood progenitor cells (PBPC) for clinical transplantation or research applications aims to effectively isolate or deplete specific cell populations, utilizing primarily magnetic or fluorescence activated sorting methods. Here, we investigated the performance of microfluidic acoustophoresis for the separation of lymphocyte subsets from PBPC, and present a novel method for

A Context Management Framework for Context-Aware Applications in Mobile Spaces

Purpose – The rapid proliferation of mobile context aware applications has resulted in an increased research interest towards developing specialized context data management strategies for mobile entities. The purpose of this paper is to aim to develop a new way to model mobile entities and manage their contexts accordingly. Design/methodology/approach – This paper proposes the concept of “Mobile

Late Ordovician shelly faunas from Jamtland: palaeocommunity development along the margin of the Swedish Caledonides

Late Ordovician shelly faunas occur at several localities in the Ostersund area of Jamtland (Sweden) and developed against a background of intense and rapid global climate change. In the eastern part, approximately in the middle parts of the Krykas Quartzite, and in the western part in the uppermost Kogsta Siltstone changes in faunas and sedimentary patterns provide regional evidence of these glob

Increased C1q, C4 and C3 deposition on platelets in patients with systemic lupus erythematosus - a possible link to venous thrombosis?

Objective: Patients with systemic lupus erythematosus (SLE) have an increased risk of developing vascular diseases (VD) such as myocardial infarction, stroke and venous thrombosis, which can only partly be explained by traditional risk factors. The role of platelets in this process has not been extensively studied. Platelet activation supports complement binding to the platelet surface, and incre

Hunting for Protein Markers of Hypoxia by Combining Plasma Membrane Enrichment with a New Approach to Membrane Protein Analysis

Nontransient hypoxia is strongly associated with malignant lesions, resulting in aggressive behavior and resistance to treatment. We present an analysis of mRNA and protein expression changes in neuroblastoma cell lines occurring upon the transition from normoxia to hypoxia. The correlation between mRNA and protein level changes was poor, although some known hypoxia-driven genes and proteins corre

Människan på gott och ont : Freuds tragiska antropologi

Vårvintern 1915 författar Freud ett par essäer där han sammanfattar sina reflektioner över kriget, vilka han senare under året publicerar under rubriken ”Tidsligheter om krig och död”. Artikeln tar sitt avstamp i denna text och reflekterar över Freud som kultur- och civilisationskritiker i relation till vår europeiska samtid – hundra år efter att första världskriget bröt ut.

Performance Analysis of Aluminum and Graphite Foam Heat Exchangers Under Countercurrent Arrangement

Due to the increasing power requirement and the limited available space in the vehicles, a countercurrent heat exchanger (HEX) is proposed for the position on the roof of the vehicle compartment. Furthermore, a new material, graphite foam with high thermal conductivity and low density, is a potential material for HEXs in vehicles. In order to evaluate the performance of the graphite foam HEX, the

Locomotives of local growth: The short- and long-term impact of railroads in Sweden

This paper studies the impact of railroads on 150 years of urban growth in Sweden, identifying the short- and long-term effects of a first wave of railroad construction. Difference-in-differences and instrumental variable estimates show that towns that gained access experienced substantial relative increases in population, though such growth mainly reflected a relocation of economic activity. Over

Assessment of the 3-D shape and mechanics of the proximal femur using a shape template and a bone mineral density image

Measurement of bone mineral density (BMD) by DXA (dual-energy X-ray absorptiometry) is generally considered to be the clinical golden standard technique to diagnose osteoporosis. However, BMD alone is only a moderate predictor of fracture risk. Finite element analyses of bone mechanics can contribute to a more accurate prediction of fracture risk. In this study, we applied a method to estimate the

Faceting, composition and crystal phase evolution in III-V antimonide nanowire heterostructures revealed by combining microscopy techniques

III-V antimonide nanowires are among the most interesting semiconductors for transport physics, nanoelectronics and long-wavelength optoelectronic devices due to their optimal material properties. In order to investigate their complex crystal structure evolution, faceting and composition, we report a combined scanning electron microscopy (SEM), transmission electron microscopy (TEM), and scanning

Education-occupation mismatch: Is there an income penalty?

This paper adds to the sparse literature on the consequences of education–occupation mismatches. It examines the income penalty for field of education–occupation mismatches for men and women with higher education degrees in Sweden and reveals that the penalty for such mismatches is large for both men and women. For mismatched men the income penalty is about twice as large as that found for US men,

Long-term results of positron emission tomography-directed management of the neck in node-positive head and neck cancer after organ preservation therapy.

The current study presents the long-term results from a study designed to evaluate a restaging positron emission tomography (PET) directed policy whereby neck dissections were omitted in all node positive head and neck squamous cell carcinoma (N+HNSCC) patients with PET-negative lymph nodes after definitive radiotherapy (RT), with or without chemotherapy.