The role of polyamines in cell cycle progression
In an attempt to shed light on the role of the polyamines, putrescine, spermidine, and spermine in cell cycle progression, polyamine biosynthesis has been analyzed during the cell cycle of Chinese hamster ovary cells, and cell cycle kinetics have been investigated in cells treated with polyamine biosynthesis inhibitors. Cells were synchronized with the mitotic detachment technique, and at various