The prospect of being able to efficiently inject large plasmids in insulin-producing beta cells is very attractive for diabetes research. However, conventional transfection methods suffer from high cytotoxicity or low transfection efficiency, which negatively affect their outcome. In contrast, nanostraw electroporation is a gentle method that can provide a high transfection efficiency while mainta

"Storsjöodjuret”, eller “The Great Lake Monster”, är ett undflyende fenomen i sjön Storsjön, belägen i landskapet Jämtland i norra Sverige. Denna avhandling i ämnet humanekologi undersöker hur det sammankopplingar av det sociala, det kulturella, det historiska och det lokala påverkar formandet av detta svenska kryptid, eller “dolda djur”. Syftet med studien är att visa hur detta vetenskapligt ännuStorsjöodjuret, or The Great Lake Monster, is an elusive phenomenon in lake Storsjön, situated in the province of Jämtland in Northern Sweden. This dissertation in Human Ecology investigates how the intricate web of the social, the cultural, the historical, and the local influence the shaping of this Swedish cryptid, or “hidden animal”. The purpose of the study is to demonstrate how this scientifi

In wildland fires, burning particles of vegetative material can be lofted by the fire plume and are subsequently transported horizontally by cross wind. Depending on the state of the firebrands (flaming, smoldering, inert hot, inert cold) upon landing they bear the potential to cause secondary fires. The present work introduces the reader to existing theoretical analyses of the problem of combusti

In this thesis, we investigate low-dimensional magnetic systems from the theoretical points of view. To address situations with several and distinct magnetic interactions, we develop different frameworks, including a magnon self-energy approach, a spin dynamical exchange-correlation (xc) field formalism and a scheme combining Matrix Product States method and exact diagonalization/nonequilibrium Gr

Neutron spectroscopy uniquely and non-destructively accesses diffusive dynamics in soft and biological matter, including for instance proteins in hydrated powders or in solution, and more generally dynamic properties of condensed matter on the molecular level. Given the limited neutron flux resulting in long counting times, it is important to optimize data acquisition for the specific question, in

Protein interactions in solution and the question of cluster formation are of paramount importance to a wide range of research fields and industrial applications. Protein clustering can arise due to a delicate interplay between the short-range attraction and the long-range repulsion in the interaction potential. This study employs small angle X-ray scattering (SAXS) to examine the clustering behav

Bacterial exopolysaccharides (EPS) have emerged as one of the key players in the field of heavy metal-contaminated environmental bioremediation. This study aimed to characterize and evaluate the metal biosorption potential of EPS produced by a novel Psychrobacillus strain, NEAU-3TGS, isolated from an iron ore deposit at Tamra iron mine, northern Tunisia. Genomic and pan-genomic analysis of NEA

PURPOSE: There is a lack of validated imaging biomarkers for prediction of response to peptide receptor radionuclide therapy (PRRT). The primary objective was to evaluate if tumour burden at baseline PET/CT could predict treatment outcomes to PRRT with [ 177Lu]Lu-DOTA-TATE. Secondary objectives were to evaluate if there was a correlation between tumour burden and mean tumour absorbed dose (AD) dur

Within the new generation of structural materials having heterogeneous microarchitectures, one of the top performers is harmonic structure (HS). Herewith, the exciting discovery of self-similarity in their stress–strain behavior is reported. HS materials consist of the 3D skeleton of ultrafine grains (UFG) encompassing coarse-grained (CG) counterparts. Our discovery simplifies the mathematical des

I den här avhandlingen, syftar jag till att utforska kopplingarna mellan natur, konflikt och fred som bygger på litteratur från freds- och konflikstudier och miljöfredsbyggande. Jag hävdar att miljöfrågor, särskilt relaterade till fördelningen av naturresurser, är centrala för att förstå strukturella förhållanden möjliggör både konflikt och fred. För att svara på förskningsfrågan utforskar jag hurIn this dissertation, I aim to explore the links between nature, conflict, and peace building on literature from peace and conflict studies and environmental peacebuilding. I argue that environmental issues, especially related to the distribution of natural resources, are central to understanding structural conditions allowing for both conflict and peace. In order to answer the research question,

Increased concern was raised globally at the outbreak of COVID-19 that victims of domestic violence would be even more at risk when isolated with a violent partner and out of reach of support due to restrictions. Swedish staff in violence against women services prepared for increased calls for help. Instead, a worrying silence arose in a time and place of high uncertainty. This paper analyses the

Diabetes mellitus (DM) is a risk factor for the development of ulnar nerve entrapment (UNE). Differences in surgical outcomes for UNE between patients with and without DM have been reported, but studies on presurgical management are scarce. This study aimed to evaluate the presurgical management of UNE in patients with (DM diagnosis < 2 years of UNE diagnosis) and without DM regarding the level of

Firms compete on price and quality, but can also compete on issues of inclusion and sustainability, including gender and design as a competitive strategy. To develop a company brand that projects an image of an inclusive organization is one strategy that businesses can deploy to develop a unique selling proposition. Another possibility is to adapt product designs to include more groups within a po