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The recruitment of antigen-specific T lymphocytes to the intestinal mucosa is central to the development of an effective mucosal immune response, yet the mechanism by which this process occurs remains to be fully defined. Here we show that the CC chemokine receptor 9 (CCR9) is selectively and functionally expressed on murine alpha(E)beta(7)(+) naive CD8alphabeta(+) lymphocytes and a subset of rece

The population-based Reykjavik Heart Study, started in 1967, aims at finding and evaluating risk factors for cardiovascular diseases. It included 4,137 men born between 1907 and 1934 and we examined all fractures recorded in these subjects from January 1977 until the end of December 2000, or death. Their mean age at the start of this study was 54 (42-69) years and the mean follow-up time 19 years.

In a screening of basidiomycete cultures from Chile for the production of antibiotics we identified a Serpula himantoides strain as a producer of metabolites inhibiting the growth of bacteria and fungi. Bioactivity guided purification resulted in the isolation of four new antibiotics. Their structures were elucidated by spectroscopic methods. All four compounds are succinimide and maleimide deriva

An 8-bit 100-MHz CMOS linear interpolation digital-to-analog converter (DAC) is presented. It applies a time-interleaved structure on an 8-bit binary-weighted DAC, using 16 evenly skewed clocks generated by a voltage-controlled delay line to realize the linear interpolation function. The linear interpolation increases the attenuation of the DAC's image components. The requirement for the analog re

The kinetics of the direct synthesis of acrylonitrile from propane on V-Sb-Al-(W) mixed oxides indicate that acrylonitrile (ACN) forms by two parallel pathways, one directly from propane and the second, which is the prevalent path, through the intermediate formation of propylene (C3=). The limiting factor in the formation of ACN is the relative slowness of the step of allylic oxidation to ACN of t

This paper reports speech articulator gestures in Swedish, Bulgarian, and Greenlandic to study universal and language-specific components in articulation. This work is based on analysis of movements of individual articulators from x-ray motion films of speech, and continues from previous reports from this study by Wood [J. Phon. 7, 25–43 (1979); 19, 281–292 (1991); Proc. 3rd Conf. I.C.P.L.A., 191–

A mathematical model was developed for the drying of paper in a multi-cylinder drying section. The model is based on the unsteady state, one-dimensional heat conduction equation, which is applied to both the cylinder shell and the paper web. No internal mass transfer phenomena were modeled explicitly. Great emphasis ws placed on finding the proper heat and mass transfer coefficients that are integ

Denna rapport är författad inom pilotprojektet ”Maritima risker i Öresundsområdet” (Sundrisk) där projektets avsikt var att genomföra en integrerad riskanalys av maritima risker i Öresundsområdet. En serie rapporter från olika discipliner har författats inom pilotprojektet. Målsättningen med delprojektet som presenteras i denna rapport var att identifiera och belysa brister i organisation och män

Barn, Ungdomar, Fetma

The CD40-CD40L interaction plays a critical role in both humoral and cellular immune responses and interfering antibodies have been suggested as an effective approach for the treatment of lymphomas and autoimmune diseases. In this study we have profiled a panel of mouse antihuman CD40 monoclonal antibodies (MoAbs), regarding their CD40 binding affinity and epitope-specificity relative to the CD40L

The concept of measure functions for classifier performance is suggested. This concept provides an alternative way of selecting and evaluating learned classifiers, and it allows us to define the learning problem as a computational problem.

Based on the known age-related loss of Purkinje cells (PC) in the cerebellum, this study focuses on whether a marked loss of PC occurs in individuals of very high age. The inferior olive, which is intimately connected with the cerebellum anatomically as well as functionally, was also studied. The study group included 15 nondemented and basically healthy cases aged 32-104 years. Linear neuronal den

Popular Abstract in Swedish En omorganisation av det svenska Vägverket har medfört ett behov för dem att fungera som en professionell beställare enbart, utan utförande i egen regi. Det har naturligtvis också medfört en förändring i hur man hanterar upphandlingen av vägunderhåll. En väghållares främsta uppgift är att underhålla befintliga anläggningar och se till at de fungerar som avsett. Den näsA reorganization of the Swedish National Road Administration (SNRA) has urged a demand to work as a professional agency only, without any work by direct labor. This structure has enforced a change in how to handle the pavement maintenance and performance contracts are being promoted since they encourage product development and sustainability. Furthermore, SNRA desires to use the road network as a

We examined the physical and social function of patients surviving 10 years after internal fixation of a hip fracture. 74 out of 362 patients were alive 10 years after their fracture. In 47 survivors after cervical fracture, secondary hip arthroplasties had been performed in 25, and nails had been extracted in 13. The implants had been removed in 8 of 27 with trochanteric fracture. 58 survivors we