Prostate cancer is the most common form of cancer in Sweden. The past decade has seen a tremendous development of new methods for diagnosing, staging, treating and rehabilitating men with suspicious or confirmed prostate cancer. This development necessitates a multidisciplinary and multiprofessional approach to the management of men with suspicious or confirmed prostate cancer. A recent survey sho

Birds migrating between distant locations regularly perform long continuous flights lasting several days. What compass mechanism they use is still a mystery. Here, we use a novel approach, applying an individual-based model, taking compass mechanisms based on celestial and geomagnetic information and wind into account simultaneously, to investigate what compass mechanism likely is used during long

The paper presents a study of key aspects in the design of a flexible unified data plane capable of integrating both fronthaul and backhaul transport in future 5G systems. In this study, we first review candidate access and multiplexing technologies from the state of the art and assess their capability to support legacy and new fronthaul and backhaul traffic. We then propose a new design framework

The principles of mutual trust and mutual recognition are well established features of EU law. On a technical level, it is clear that the principles may require adoption of foreign levels of protection in individual cases as well as in legislation. At a closer look, however, the principles through “the rule of reason” also may imply quite the opposite: the imposing of domestic requirements on fore

The hysteretic behavior of flashback (FB) and flash forward (FF) in methane and natural gas flames, stabilized by a low swirl fuel injector, is investigated using high speed OH* chemiluminescence and particle image velocimetry. Due to the lack of vortex breakdown, the two mechanisms discussed are boundary layer and turbulence induced FB. Two hysteresis cycles were identified, one when FB is induce

Activated sludge processes (ASPs) consisting of a plug-flow reactor (PFR) and a settler are analyzed in steady-state operation using a reduced model consisting of one soluble substrate and one particulate biomass component modelling the dominating biological process. Monod biomass growth rate is assumed. Two settler models are studied. One is the commonly used ideal settler, or point settler, whic

Background Microsatellite instability arises due to defect mismatch repair (MMR) and occurs in 10–20% of sporadic colorectal cancer. The purpose was to investigate correlations between defect MMR, prognosis and heredity for colorectal cancer in first-degree relatives. Material and methods Tumour tissues from 318 patients consecutively operated for colorectal cancer were analysed for immunohistoche

Ett nyupptäckt medeltida stenhus i Färlövs kyrkby, Östra Göinge, blev hösten 2011 föremål för en kortvarig, inledande undersökning. En välbevarad, aristokratiskt präglad anläggning har börjat framträda, i ett läge strax väster om Färlövs romanska stenkyrka med sina välkända tvillingtorn. En medeltida huvudgård i kyrkbyn är känd i dokumenten, och här finns ett ännu något oklart men intressant samba

Severe infections are recognized complications of coeliac disease (CD). In the present study we aimed to examine whether individuals with CD are at increased risk of invasive pneumococcal disease (IPD). To do so, we performed a population-based cohort study including 29 012 individuals with biopsy-proven CD identified through biopsy reports from all pathology departments in Sweden. Each individual

Theoretical computations (molecular dynamics and combined quantum chemical and molecular mechanical geometry optimizations) have been performed on horse liver alcohol dehydrogenase. The results provide evidence that Glu‐68, a highly conserved residue located 0.47 nm from the catalytic zinc ion, may intermittently coordinate to the zinc ion. Structures with Glu‐68 coordinated to the zinc ion are al

Methane (CH4) emissions from arctic tundra typically follow relations with soil temperature and water table depth, but these process-based descriptions can be difficult to apply to areas where no measurements exist. We formulated a description of the broader temporal flux pattern in the growing season based on two distinct CH4 source components from slow and fast-turnover carbon. We used automatic

Polychlorinated-biphenyls (PCBs) were introduced in the late 1920s and used until the 1970s when they were banned in most countries due to evidence of environmental build-up and possible adverse health effects. However they still persist in the environment, indoors and in humans. Indoor air in contaminated buildings may confer airborne exposure markedly above background regional PCB levels. To dat

Occupational exposure is an important, global cause of respiratory disease. Unlike many other non-communicable lung diseases, the proximal causes of many occupational lung diseases are well understood and they should be amenable to control with use of established and effective approaches. Therefore, the risks arising from exposure to silica and asbestos are well known, as are the means of their pr

Background: Elite athletes, independent of sport, have increased risk of developing asthma, but little is known about sex difference among adolescent athletes. Objective: To investigate and compare sex-related differences according to symptoms and treatment of asthma, allergy, and health among elite athletes and a reference group. Methods: Adolescent elite swimmers (n = 101), tennis players (n = 8

To improvise together for the pure curiosity, joy, and beauty of it constitutes a central but often neglected ability of human beings. Integrating pragmatic, practical, and technical skills with conceptual understanding, improvisation is adaptive and collaborative. It seems made to counter the challenges of living in a fleeting present, unconstrained by physical and historical boundaries, and very