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Civil Defence (Re)Emerged : A Multi-Level Perspective on Policy Developments in Post-Crimea Europe

Denna avhandling undersöker (åter)uppbyggnaden av civilt försvar i Europa efter Rysslands annektering av Krim 2014. Mer specifikt analyserar den befintliga uppfattningar om civilt försvar och hur dessa formas i ett flernivåsammanhang, med fokus på samspelet mellan nationella, regionala och internationella institutioner. Genom ett diskursivt institutionellt perspektiv betonar avhandlingen den dynamThis dissertation examines the (re)emergence of civil defence in Europe in the aftermath of Russia's annexation of Crimea in 2014. More specifically, it investigates the existing conceptions of civil defence and how these are shaped in a multi-level institutional context, focusing on the interplay between national, regional, and international levels. Through the lens of discursive institutionalism

Antibiotic prophylaxis and incidence of infection following elbow arthroplasty : a nationwide study

BACKGROUND AND PURPOSE: Periprosthetic joint infection (PJI) after elbow arthroplasty is a serious complication. Evidence of the best antibiotic prophylaxis for elbow arthroplasty is lacking. We aimed to investigate the regimens presently used in Sweden, incidence of PJI, and the bacteria most frequently found in elbow PJI.METHODS: A questionnaire was sent out to all Swedish units performing elbow

Integrating machine learning with process-based glacio-hydrological model for improving the performance of runoff simulation in cold regions

Hydrological modelling is essential for effective water resources management, as it represents complex physical processes through mathematical equations to improve our understanding of the water cycle. FLEXG is a glacio-hydrological model that has been successfully applied and found to perform well in glacierized regions. This study seeks to improve the capability of classical FLEXG model for glac

Super-resolution imaging pinpoints the periodic ultrastructure at the human node of Ranvier and its disruption in patients with polyneuropathy

The node of Ranvier is the key element in saltatory conduction along myelinated axons, but its specific protein organization remains elusive in the human species. To shed light on nanoscale anatomy of the human node of Ranvier in health and disease, we assessed human nerve biopsies of patients with polyneuropathy by super-resolution fluorescence microscopy. We applied direct stochastic optical rec

Parent-of-origin effects in the life-course evolution of cardiometabolic traits

AIMS/HYPOTHESIS: Cardiometabolic traits are heritable, and some display parent-of-origin effects, which indicates preferential inheritance from one parent or parental bias. Most studies of these phenomena have focused on adult populations. We aimed to investigate the heritability and parent-of-origin effects on cardiometabolic traits in a birth cohort with serial measurements to determine whether

Epigenome-wide association study of objectively measured physical activity in peripheral blood leukocytes

BACKGROUND: Few studies have explored the association between DNA methylation and physical activity. The aim of this study was to evaluate the association of objectively measured hours of sedentary behavior (SB) and moderate physical activity (MPA) with DNA methylation. We further aimed to explore the association between SB or MPA related CpG sites and cardiometabolic traits, gene expression, and

Clinical use of polygenic scores in type 2 diabetes: challenges and possibilities

Resulting from a combination of genetic and environmental factors, type 2 diabetes is highly heterogeneous in manifestation and disease progression, with the only common feature being chronic hyperglycaemia. In spite of vigorous efforts to elucidate the pathogenetic origins and natural course of the disease, there is still a lack of biomarkers and tools for prevention, disease stratification and t

High Hopes and Hard Lessons : How Problems Are Represented in Swedish Teacher Education Reform

In this paper, I draw on my background as an educational scientist with roots in sociology and gender studies to explore how public debate, political reforms, and policy documents shape Swedish teacher education with the aim of reforming not only the school system but also Swedish society. Historically, teacher education in Sweden has been influenced by visionary ideals, particularly with the intr

High-fidelity 3D live-cell nanoscopy through data-driven enhanced super-resolution radial fluctuation

Live-cell super-resolution microscopy enables the imaging of biological structure dynamics below the diffraction limit. Here we present enhanced super-resolution radial fluctuations (eSRRF), substantially improving image fidelity and resolution compared to the original SRRF method. eSRRF incorporates automated parameter optimization based on the data itself, giving insight into the trade-off betwe

The Association Between Women's Perception of Birth During the Pandemic, Companion of Choice and Support From Health Professionals : A Cross-Sectional Study in 20 Countries in the WHO European Region

BACKGROUND: Mitigation measures implemented in response to the COVID-19 pandemic led to significant changes in maternity care across Europe, including restrictions on companions during labor and birth. This cross-sectional study explores the association between the presence of a companion of choice and a positive perception of the birth experience. Additionally, it explores the association between

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The current linear economic system is based on the extraction of natural resources, the transformation of raw materials and the disposal of waste, leading to the environmental and economic depletion of resources and society. The circular economy proposes the circularity of materials, evaluating post-consumption waste and proposing a waste hierarchy called preparation for reuse (PfR), as set out in

Technological competencies and firm performance : analyzing the importance of internal and external competencies

In this paper, we analyze the relationship between technological competencies (TC) and firm performance. Theoretically, the importance of TC is well established and widely accepted. Therefore, it is surprising that a number of empirical studies have been unable to confirm a substantial positive relationship between TC and firm performance. We identify two major reasons for this: [i] affected by th