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Cognitive abnormalities and cerebral perfusion defects in a community-dwelling cohort of elderly men with MMSE within the normal range

Objectives: Mini Mental State Examination’s (MMSE’s) sensitivity in its upper level is questioned, hence we investigated cognitive abnormalities and defects in regional cerebral blood flow (rCBF) in elderly with MMSE scores ≥24. Methods: One hundred and four men at age 81 with MMSE scores ≥24 (mean 28.4 ± 1.7), no dementia or stroke, were examined with neuropsychological test battery, and their rC

Migration and wintering of a declining seabird, the thick-billed murre Uria lomvia, on an ocean basin scale : Conservation implications

Pelagic seabirds are exposed to an array of potential threats during the non-breeding period, and effective management of these threats on a large scale requires knowledge of which populations winter where. Thick-billed murres (Uria lomvia) are emblematic of this conservation challenge, since they breed widely in the circumpolar Arctic, with many declining populations in the Atlantic. Threats faci

Arthroscopically assisted anterior cruciate ligament reconstruction with bone-patellar tendon-bone autograft without wound drainage : Short- to middle-term outcome

Introduction: Several studies have suggested that anterior cruciate ligament reconstruction (ACLR) without wound drainage has no impact on long-term follow-up. Aim: To investigate a prospective patient series as measured by the patient-administered disease-specifc questionnaire Knee injury and Osteoarthritis Outcome Score (KOOS). Material and methods: The study included 101 consecutive patients (7

Observations on normal EEG activity in different brain regions of the unrestrained swine

This methodological and electrophysiological study was undertaken with the aim of obtaining possibilities for evaluating objectively the ethical value of using high concentration CO2 inhalation as pre-slaughter anaesthesia for swine. A technique for implantation of recording electrodes into the porcine neocortex and limbic system is described, as are results of EEG recording from these brain regio

The evolution of an enterprise system implementation methodology by adaptation through reflexivity

In spite of an Enterprise Systems Implementation Methodology's (ESIM's) potential and significance for Enterprise Systems implementation, little attention has been paid to its evolution in ES literature. Moreover, current studies reveal contradictory findings and provide a fragmented understanding. The purpose of this paper is to provide a framework underpinned by a morphogenetic approach for expl

Transient neocortical, hippocampal and amygdaloid EEG silence induced by one minute inhalation of high concentration CO2 in swine

The study is part of a series of investigations performed with the ultimate goal of obtaining an objective evaluation of the ethical aspects and the narcotic efficiency of CO2 inhalation used as pre-slaughter anaesthesia for swine. Six Yorkshire swine were exposed twice to 80% CO2 for I min during simultaneous recording of the EEGs from the frontal neocortex, the dorsal hippocampus, and the amygda

The 2016 update of the International Study Group (ISGPS) definition and grading of postoperative pancreatic fistula : 11 Years After

Background: In 2005, the International Study Group of Pancreatic Fistula developed a definition and grading of postoperative pancreatic fistula that has been accepted universally. Eleven years later, because postoperative pancreatic fistula remains one of the most relevant and harmful complications of pancreatic operation, the International Study Group of Pancreatic Fistula classification has beco

Conodont faunal dynamics across the middle and upper ordovician boundary in the Yichang area, western Hubei province, South China

A total of 6094 conodont specimens, assigned to 18 genera and 27 species, have been recovered from the uppermost Kuniutan and Miaopo formations, spanning the latest Darriwilian - early Sandbian in age, at the Jieling section, Yichang, Hubei Province. Three conodont zones have been recognized, i.e., in ascending order, the Pygodus serra Zone, the Pygodus anserinus - Yangtzeplacognathus jianyeensis

Bimetallic nickel and palladium complexes for catalytic applications

South Africa is a mineral-rich country and one area in which minerals can be very important is catalysis. Over an extended period of time, homogeneous catalysis has grown to become very useful, particularly in the chemical and pharmaceutical industries. The organometallic compounds required in the catalysis industry have advanced from metallocenes to an alternative in the form of α-diimines. Most

Single Active Site Mutation Causes Serious Resistance of HIV Reverse Transcriptase to Lamivudine : Insight from Multiple Molecular Dynamics Simulations

Molecular dynamics simulations, binding free energy calculations, principle component analysis (PCA), and residue interaction network analysis were employed in order to investigate the molecular mechanism of M184I single mutation which played pivotal role in making the HIV-1 reverse transcriptase (RT) totally resistant to lamivudine. Results showed that single mutations at residue 184 of RT caused