Search results

Filter

Filetype

Your search for "*" yielded 533206 hits

Contribution of child ABC-transporter genetics to prenatal MeHg exposure and neurodevelopment

BACKGROUND: There is emerging evidence that exposure to prenatal methylmercury (MeHg) from maternal fish consumption during pregnancy can differ between individuals due to genetic variation. In previous studies, we have reported that maternal polymorphisms in ABC-transporter genes were associated with maternal hair MeHg concentrations, and with children's early neurodevelopmental tests. In this st

Förvaltningsorgan under parlamenten i Norden

I de nordiska länderna finns ett antal förvaltningsorgan som på olika sätt är knutna till parlamenten. Hit hör exempelvis Folketingets Ombudsmand(Danmark), Statens revisionsverk (Finland), Ríkisendurskoðun(Riksrevisionen, Island), Stortingets kontrollutvalg for etterretnings-,overvåkings- og sikkerhetstjeneste, EOS-utvalget (Norge) och Valprövningsnämnden (Sverige). Sådana organ kan ses som en avvIn a Western European system based on a traditional separation of powers, public administration is as a rule organised under the Government (or Cabinet), as part of the Executive. In addition to this kind of state authorities, the Nordic countries feature a number of administrative bodies attached to the Parliaments. This category includes Parliamentary Ombudsmen, National Banks, and National Audi

The Swedish Monarch as the Head of State : Between Democratic Ideals and Royal Traditions

The Swedish constitution features a uniquely limited role of the King or Queen Regnant as Head of State among the European monarchies. Other constitutionalmonarchies, including the Scandinavian neighbouring countries of Denmark andNorway, award the Head of State certain formal legal powers. Contrastingly, theSwedish Head of State has no such role. Under the 1974 Instrument of Government, the King

Healthcare resource use of patients with transthyretin amyloid cardiomyopathy

Aims: Transthyretin amyloid cardiomyopathy (ATTR-CM) is the cardiac manifestation of transthyretin amyloidosis (ATTR). The aim of this study was to estimate healthcare resource use for ATTR-CM patients compared with heart failure (HF) patients, in Denmark, Finland, Norway, and Sweden. Methods and results: Data from nationwide healthcare registers in the four countries were used. ATTR-CM patients w

Gene profiling reveals a contact allergy signature in most positive Amerchol L-101 patch-test reactions

Background: Diagnosis of contact allergy (CA) to Amerchol L-101 (AL-101), a marker for lanolin allergy, is problematic. Positive patch-test reactions are frequently doubtful or weakly positive and difficult to associate with clinical relevance. Objective: To gain further insight on the allergic or irritant nature of skin reactions induced by AL-101 patch test. Methods: We re-tested in a dose–respo

Surface states in noncentrosymmetric superconductor BiPd

BiPd is a noncentrosymmetric superconductor with Dirac-like surface states on both (010) and (01¯0) faces. The Dirac cone on (010) surface is intense and appears at 0.66 eV binding energy. These states have drawn much attention due to contradictory reports on dimensionality and the momentum of these Dirac fermions. We have studied the properties of these Dirac fermions using varied photon energies

Antigen-Presenting B Cells Program the Efferent Lymph T Helper Cell Response

B cells interact with T follicular helper (Tfh) cells in germinal centers (GCs) to generate high-affinity antibodies. Much less is known about how cognate T–B-cell interactions influence Th cells that enter circulation and peripheral tissues. Therefore, we generated mice lacking MHC-II expressing B cells and, by thoracic duct cannulation, analyzed Th cells in the efferent lymph at defined interval

Inorganic ligands-mediated hole attraction and surface structuralreorganization in InP/ZnS QD photocatalysts studied via ultrafast visibleand midinfrared spectroscopies

Photoinduced carrier dynamical processes dominate the optical excitation properties of photocatalysts and further determine the photocatalytic performance. In addition, as the electrons generally possess a faster transfer rate than holes, hole transfer and accumulation are critical, and they play the key efficiency-limiting step during the photocatalytic process. Therefore, a comprehensive underst

Short-term, intermediate-term and long-term risks of acute coronary syndrome in cohorts of patients with RA starting biologic DMARDs : Results from four Nordic countries

Objectives: To compare the 1-year, 2-year and 5-year incidences of acute coronary syndrome (ACS) in patients with rheumatoid arthritis (RA) starting any of the biologic disease-modifying antirheumatic drugs (bDMARDs) currently available in clinical practice and to anchor these results with a general population comparator. Methods: Observational cohort study, with patients from Denmark, Finland, No

Dissolution of What? The Self Lost in Self-Transcendent Experiences

In this study, we investigate the phenomenology of self-transcendent experiences, in which the usual sense of self is lost. Based on a taxonomy of nine aspects of self and three types of content of consciousness, we compare ten accounts of such experiences acquired through in-depth interviews. Sense of separateness and identification with body and narrative self were reported as lost in all of the

Phylogeographic Assessment Reveals Geographic Sources of HIV-1 Dissemination Among Men Who Have Sex With Men in Kenya

HIV-1 transmission dynamics involving men who have sex with men (MSM) in Africa are not well understood. We investigated the rates of HIV-1 transmission between MSM across three regions in Kenya: Coast, Nairobi, and Nyanza. We analyzed 372 HIV-1 partial pol sequences sampled during 2006–2019 from MSM in Coast (N = 178, 47.9%), Nairobi (N = 137, 36.8%), and Nyanza (N = 57, 15.3%) provinces in Kenya

Fractionation of sugar beet pulp polysaccharides into component sugars and pre-feasibility analysis for further valorisation

Sugar beet pulp (SBP) is a by-product formed in large amounts during the production of refined sugar and is currently used as a low-cost feed for livestock. The dry SBP comprises largely three polysaccharides (75–85%), cellulose, hemicellulose and pectin, whose component sugars constitute potential valuable feedstock for producing building blocks for chemicals and materials. In the present study,

Multivariate mining of an alpaca immune repertoire identifies potent cross-neutralizing SARS-CoV-2 nanobodies

Conventional approaches to isolate and characterize nanobodies are laborious. We combine phage display, multivariate enrichment, next-generation sequencing, and a streamlined screening strategy to identify numerous anti-severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) nanobodies. We characterize their potency and specificity using neutralization assays and hydrogen/deuterium exchange m

A Machine-Learning-Based Bibliometric Analysis of the Scientific Literature on Anal Cancer

Squamous-cell carcinoma of the anus (ASCC) is a rare disease. Barriers have been encountered to conduct clinical and translational research in this setting. Despite this, ASCC has been a prime example of collaboration amongst researchers. We performed a bibliometric analysis of ASCC-related literature of the last 20 years, exploring common patterns in research, tracking collaboration and identifyi

Conversion Narratives of Unaccompanied Refugee Minors in the Church of Sweden

From 2014 to 2016, 44,617 unaccompanied refugee minors (URM) arrived and sought asylum in Sweden. Since their arrival, the Church of Sweden (CoS) has received hundreds of these young people seeking to join the church and be baptised as Christians. This phenomenon is notable in an institution that is otherwise declining in membership and which is not known for actively recruiting new members. While

High CD34 surface expression in BCP-ALL predicts poor induction therapy response and is associated with altered expression of genes related to cell migration and adhesion

Minimal residual disease (MRD) constitutes the most important prognostic factor in B-cell precursor acute lymphoblastic leukemia (BCP-ALL). Flow cytometry is widely used in MRD assessment, yet little is known regarding the effect of different immunophenotypic subsets on outcome. In this study of 200 BCP-ALL patients, we found that a CD34-positive, CD38 dim-positive, nTdT dim-positive immunophenoty