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Evolution of free, complexed, and total serum prostate-specific antigen and their ratios during 1 year of follow-up of men with febrile urinary tract infection
Objectives. To determine the serum values of free, complexed, and total prostate-specific antigen (PSA) and their ratios in men with febrile urinary tract infection (UTI) during 1 year of follow-up. Methods. A total of 54 men were prospectively enrolled in the study, and serum samples were obtained at the acute stage of the UTI and after 1, 3, 6, and 12 months. Results. Most men had a rise (median
Treatment of early heart failure: an ACEI or a beta-blocker first?
Nanoelectrochemical transducers for (bio-) chemical sensor applications fabricated by nanoimprint lithography
Nanometer-structured transducers for commercial use in pharmaceutical, medical or (bio-) chemical analysis have so far been hardly accessible since they could not be produced by parallel lithography techniques at reasonable costs. We introduce here a method on. how to fabricate nanometer-structured interdigitated array electrodes including interconnections and bond pads in the micrometer range in
Association of metabolic gene polymorphisms with tobacco consumption in healthy controls
Polymorphisms in genes that encode for metabolic enzymes have been associated with variations in enzyme activity between individuals. Such variations could be associated with differences in individual exposure to carcinogens that are metabolized by these genes. In this study, we examine the association between polymorphisms in several metabolic genes and the consumption of tobacco in a large sampl
Effects of animal selection on milk composition and processability.
One goal of animal breeding is to increase the economic output through increased production, improved milk quality, and cow health. The objective of this study was to evaluate genetic progress in relation to milk composition, processability, and yield as a correlated response to selection for the Swedish breeding objective. Dairy cows with high genetic merit, classified as elite dairy cows, of the
Enrichment of phosphoproteins and phosphopeptide derivatization identify universal stress proteins in elicitor-treated Arabidopsis
Protein phosphorylation is a key biological process that regulates reactions involved in plant-microbe interactions. The phosphorylated form of a protein often represents only a small fraction of the total population and can be problematic to analyze in a mass spectrometer. We demonstrate how a titanium dioxide (TiO2) resin can be employed for the enrichment of phosphoproteins, as well as a method
Optimal recall length in survey design
Self-reported data collected Via Surveys are a key input into a wide range of research conducted by economists. It is well known that Such data are subject to measurement error that arises when respondents are asked to recall past utilisation. Survey designers Must determine the length of the recall period and face a trade-off as increasing the recall period provides more information, but increase
Multiple alpha-galactosidases from Aspergillus niger: purification, characterization, and substrate specificities
Enzymes with α-galactosidase activity are produced by many organisms, often in multiple forms. Here we compare the biochemical and hydrolytic properties of four major α-galactosidase forms (α-gal I-IV) that were purified from the culture filtrate of Aspergillus niger. α-Gal II, III and IV appear to be isoforms of the same enzyme, and N-terminal amino acid sequence data suggest that they are closel
Regulation of the cyclin A1 protein is associated with its differential subcellular localization in hematopoietic and leukemic cells.
CO2 elimination at varying inspiratory pause in acute lung injury
Previous studies have indicated that, during mechanical ventilation, an inspiratory pause enhances gas exchange. This has been attributed to prolonged time during which fresh gas of the tidal volume is present in the respiratory zone and is available for distribution in the lung periphery. The mean distribution time of inspired gas (MDT) is the mean time during which fractions of fresh gas are pre
Orthostatic hypotension and low blood pressure in organic dementia: a study of prevalence and related clinical characteristics
OBJECTIVE: To determine the prevalence of orthostatic hypotension (OH), low blood pressure and dizziness, falls and fractures in patients with organic dementia. DESIGN: We prospectively studied 151 patients, assessing the prevalence of OH, hypertension, heart disorders, diabetes mellitus and the use of medication possibly associated with OH. SETTING: The patients were admitted to our psychogeriatr
Reinstitutionalisation in mental-health care: comparison of data on service provision from six European countries
Objective To establish whether reinstitutionalisation is occurring in mental health care mid, if so, with What variations between Western European countries. Design Comparison of data on changes in service provision. Setting Six European countries with different traditions of mental health care that have all experienced deinstitutionalisation since the 1970s - England, Germany, Italy, the Netherla
On open shortest path first related network optimisation problems
The paper deals with flow allocation problems in IP networks using open shortest path first (OSPF) routing. Its main purpose is to discuss and propose methods for finding settlements of OSPF link weight system realising the assumed demand pattern for the given network resources (links capacities). Such settlements can result in a significantly better network performance, as compared with the simpl
An approach towards surface imprinting of the enzyme ribonuclease A
An Adsorbent showing enhanced selectivity for the enzyme RNase A was prepared by a surface imprinting procedure based on metal coordination. A metal chelating monomer, N-(4-vinyl)-benzyl iminodiacetic acid, was polymerized onto methacrylate-derivated silica particles in the presence of RNase A and metal ions. Lysozyme and RNase A were separated on the adsorbent used as stationary phase in high-per
Subchronic toxicity of Baltic herring oil and its fractions in the rat I: Fractionation and levels of organohalogen pollutants
Baltic herring (Clupea harengus) oil was extracted and fractionated. To examine the contribution to toxicity and biological effects of different halogenated organic pollutants, the herring oil and the fractions were mixed into pelleted food and given to Sprague-Dawley female rats at three levels, corresponding to a human intake of 1.6, 8.2 and 34.4 kg fish per week. Herring oil, its fractions, as
“Otiosorum hominum receptacula”: Orthodox Religious Houses in Ingria, 1615–52
The essay collects and analyses sources on the Russian Orthodox monasteries of the Swedish province of Ingria (Ingermanland). These houses have rarely been treated; their very existence is largely unknown among specialists, although they are the only Orthodox religious houses to have existed in Scandinavia before the mid-20th century, apart from those of post-1809 Finland. On the basis of printe
Repulsion between oppositely charged surfaces in multivalent electrolytes
In answer to recent experimental force measurements between oppositely charged surfaces we here reproduce the repulsion in the presence of multivalent salt using Monte Carlo simulations within the primitive model. Our osmotic pressure curves are in good agreement with experimental results. In contrast with Poisson-Boltzmann calculations, both repulsion and charge inversion are seen in the simulati
Elimination of S100B and renal function after cardiac surgery
OBJECTIVES: To determine the biologic half-life of the S100B protein and to investigate if the elimination of S100B depends on glomerular filtration rate (GFR). DESIGN: Prospective human study. SETTING: University hospital. PARTICIPANTS: Sixteen patients who underwent cardiac surgery with cardiopulmonary bypass. INTERVENTIONS: Shed mediastinal blood (autotransfusion) was returned to the patients p
Structured patient-clinician communication and 1-year outcome in community mental healthcare - Cluster randomised controlled trial
Background Patient-clinician communication is central to mental healthcare but neglected in research. Aims To testa new computer-mediated intervention structuring patient-clinician dialogue (DIALOG) focusing on patients' quality of life and needs for care. Method In a cluster randomised controlled trial, 134 key workers in six countries were allocated to DIALOG or treatment as usual; 507 people wi