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Infections with Streptococcus pyogenes exhibit a wide spectrum of infections ranging from mild pharyngitis to severe Streptococcal toxic shock syndrome (STSS). The M1 serotype of Streptococcus pyogenes is most commonly associated with STSS. In the present study, we hypothesized that Rac1 signaling might regulate M1 protein-induced lung injury. We studied the effect of a Rac1 inhibitor (NSC23766) o
This paper provides one of the first studies on the role of social media in articulating individuals’ experiences and memories and (re-)shaping collective memory in contemporary China. It investigates how social media enable and facilitate the participation of ordinary citizens in distributing and accumulating alternative narratives and memories of the past against the authoritarian version by tak
Introduction Insufficient levels of physical activity are one of the top contributors to global mortality, and it is an important public health priority to increase the proportion of physically active people in the population. The interest in environmental determinants of physical activity has been rapidly increasing over the past few years. However, a majority of the previous literature concerns
Popular Abstract in Swedish Studier av arbetsförhållande inom sjukvården har under lång tid varit förknippade med stress och sjukfrånvaro. Ett sådant problemorienterat perspektiv hänger samman med hälsa definierat som avsaknad av sjukdom (patogenes). Hälsa kan dock definieras på många olika sätt och motsatsen till patogenes är salutogenes. Ett salutogent perspektiv innebär en mer positiv syn på häThe aim was to explore and make sense of a salutogenic relationship between workplace, work and health, through an employee perspective in a Swedish nursing context. The aim was also to make sense of the role of a workplace health promotion (WHP) process, in a salutogenic public health perspective, and develop useful instruments for this kind of health-related development work. The research proces
The ability to tune the photon absorptance spectrum is an attracting way of tailoring the response of devices like photodetectors and solar cells. Here, we measure the reflectance spectra of InP substrates patterned with arrays of vertically standing InP nanowires. Using the reflectance spectra, we calculate and analyze the corresponding absorptance spectra of the nanowires. We show that we can tu
The new Red List that was recently presented by the Swedish Species Information Centre (Gärdenfors 2010) includes 746 species of fungi considered to be threatened. Compared to the previous Red List published in 2005, 36 species have been down-listed whereas 150 species have been added, thus the list has increased by 114. The changes are above all due to increased knowledge of taxonomy, ecology and
In this article I give a translation into English of the Kalmuck grammar written in Swedish by Cornelius Rahmn. This grammar was most probably written while Rahmn was a missionary in the Kalmuck area in 1819-1823. The manuscript of the grammar is kept by Uppsala University Library, and has not been published before. As an introduction, I give a short account of Rahmn’s pioneering studies on Kalmuc
Cerebral ischemia induces transcriptional upregulation of inflammatory genes in the brain parenchyma and in cerebral arteries, thereby contributing to the infarct development. The present study was designed to evaluate the involvement of calcium-calmodulin-dependent protein kinase (CaMKII) II and extracellular signal-regulated kinase1/2 (ERK1/2) on inflammatory mediators in rat cerebral arteries u
Structural fire safety in Sweden for one- and two-story assembly hall buildings have been studied with regards to recent concerns regarding a large variation in the interpretation of the regulations and the resulting fire protection of the buildings. The study has been divided into three parts. First, an analysis of the current national regulations and identification of unclear paragraphs has been
Despite several lines of evidence from preclinical and post-mortem studies suggesting that inflammation is involved in Multiple System Atrophy (MSA), no previous studies have measured peripheral indices of inflammation in MSA patients.
Background. Poor ultrafiltration is associated with worse outcomes in peritoneal dialysis (PD) patients. This might in part reflect problems associated with salt and water excess. Increasing the diffusive component of peritoneal sodium removal using low-sodium PD fluids might have beneficial effects on blood pressure (BP), thirst and fluid status that could translate into clinical benefits. Method
Abstract—Service Level Agreements (SLA) are considered a good practice not only for IT outsourcing but also for IT management within an organisation. In this paper we study the usage of SLAs in municipal IT management. Municipal IT management traditionally involves a large organisation, often with a low IT maturity, but with high requirements on software quality and information security. In this s
Background: To examine the association of education with body mass index (BMI) and waist circumference (WC) in the European Prospective Investigation into Cancer and Nutrition (EPIC). Method: This study included 141,230 male and 336,637 female EPIC-participants, who were recruited between 1992 and 2000. Education, which was assessed by questionnaire, was classified into four categories; BMI and WC
The aim of the study was to estimate the range of climate variability during the Ferdynandovian climatostratigraphic unit (MIS 13-15). The studied pollen sequences encompass two interglacials (Ferdynandovian I and II - FI and F II), the glaciation separating them (FI/II), the late glacial of the Sanian I (= Elsterian 1) and the early glacial of the Sanian II (=Elsterian 2) and are correlated with
This paper focuses on the role of ISO 14001 in environmental supply management practices in Swedish companies. It discusses the existing and potential role of ISO 14001 for three key operational tasks of environmental supply chain management: to communicate the requirements to the supplier, to motivate and enable the supplier, and to verify that the supplier follows the requirements. The study use
On several occasions during my many years of working with various snake species, I observed a significant positive relationship between body condition and head size (the former calculated from residual scores from a general linear regression of In-transformed mass on In-transformed snout-vent length). Based on results from my long-term study of water pythons (basis fuscus) this relationship is, ho
Transition problems from secondary to tertiary level in mathematics have been a recurrent issue in Sweden. This paper summarises the development during the last decades. Results from two recent research studies that illuminate the transition problem are presented. The first one, based on empirical data from a major Swedish technical university, characterises the widening gap, in content and in app
Despite the vast amount of studies focusing on bone nanostructure that have been performed for several decades, doubts regarding the detailed structure of the constituting hydroxyapatite crystal still exist. Different experimental techniques report somewhat different sizes and locations, possibly due to different requirements for the sample preparation. In this study, small- and wide-angle X-ray s
