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An increasing incidence of testicular cancer has been reported from several countries in the Western world during the last decades. According to current hypothesis, testicular cancer is initiated during the fetal period, and exposure to endocrine disruptors, i.e., xenoestrogens, has been of concern. In this investigation we studied the concentrations of the sum of 38 polychlorinated biphenyls (PCB
Popular Abstract in Swedish Tidigare trodde man att den vuxna hjärnan inte hade någon förmåga att nybilda nervceller. Detta skulle innebära att nervceller aldrig blev ersatta om de skadades eller dog. Nu vet man däremot att den vuxna hjärnan fortfarande producerar nya nervceller från särskilda moderceller, s.k. stamceller, belägna i åtminstone två områden i hjärnan: subgranulära zonen i hippocamThe adult brain constantly produces new neurons from endogenous neural progenitor cells located in at least two regions, the subgranular zone (SGZ) in dentate gyrus of the hippocampus, and the subventricular zone (SVZ). Major efforts are underway to discover the functional significance of new neurons in the adult brain. Several studies have indicated a relationship exists between newborn hippoca
Popular Abstract in Swedish Moraxella catarrhalis är en human luftvägsbakterie som ofta koloniserar de övre luftvägarna och som orsakar mellanöroninfektion hos barn. Bakterien associeras även med bihåleinfektion, laryngit och nedre luftvägsinfektioner främst hos vuxna med underliggande sjukdomar som kronisk obstruktiv lugninflammation. Forskningen fokuserar främst på moraxellas ytexponerade antigeMoraxella catarrhalis is now an established human pathogen that frequently colonizes the upper respiratory tract causing most importantly otitis media in children. It has also been associated with sinusitis, laryngitis and lower respiratory tract infections in adults with predisposing conditions such as chronic obstructive pulmonary disease (COPD). Current research mainly focuses on surface antige
High energy photon colliders (gammagamma,gammae) are based on e(-)e(-) linear colliders where high energy photons are produced using Compton scattering of laser light on high energy electrons just before the interaction point. This paper is a part of the Technical Design Report of the linear collider TESLA.(1) Physics program, possible parameters and some technical aspects of the photon collider a
A molecular understanding of volatile anesthetic mechanisms of action will require structural descriptions of anesthetic–protein complexes. Porcine odorant binding protein is a 157 residue member of the lipocalin family that features a large β-barrel internal cavity (515 ± 30 Å3) lined predominantly by aromatic and aliphatic residues. Halothane binding to the β-barrel cavity was determined using f
A mixed amphiphilic system composed of the anionic surfactant Aerosol OT (AOT), in water forming a lamellar phase, to which is added a neutral noninteracting polymer, poly(N,N-dimethylacrylamide), is studied experimentally by SAXS, H-2 NMR, and microscopy, in a range of surfactant and polymer compositions. Addition of the polymer produces a decrease in the lamellar spacing, the decrease by the pol
Background: Reduced quadriceps strength is an early finding in subjects with knee osteoarthritis, but it is not clear whether it is a cause or a consequence of knee osteoarthritis. Objective: To determine whether reduced functional performance in the lower extremity predicts the incidence or progression of radiographic knee osteoarthritis. Design: Prospective, epidemiological, population based c
A fully integrated digitally controlled phase-locked loop (PLL) used as a clock multiplying circuit is designed and fabricated. The PLL has no off-chip components and it is made from standard cells found in most digital standard cell libraries. The design is, therefore, portable between technologies as an IP block. Using a 0.35-mum standard CMOS process and a 3.0-V supply voltage, the PLL has a fr
The Children’s Revised Impact of Event Scale (CRIES) is a brief child-friendly measure designed to screen children at risk for Posttraumatic Stress Disorder (PTSD). It has good face and construct validity, a stable factor structure, correlates well with other indices of distress, and has been used to screen very large samples of at-risk-children following a wide range of traumatic events. However,
Recension av Steven Spielbergs Rädda menige Ryan (Saving Private Ryan).
We conducted a first pilot study on healthy women living in two countries with different dietary habits, Granada in the south of Spain and Malmo in the south of Sweden, in order to compare their levels of plasma phospholipid fatty acids, and to examine the relationship between the differences in food consumption. This study is part of a pilot study which is nested in the European Prospective Inves
The purpose of this work is to address the issue of applicability of single-molecule spectroscopy (SMS) results for conjugated polymers to "bulk" samples, e.g. conjugated polymer films. Also, some apparent inconsistencies in the literature on SMS regarding the photoluminescence spectral position of conjugated polymers are discussed. We present a series of photoluminescence spectra of thin films of
The field of biosensors for measuring biochemical oxygen demand (BOD) is reviewed. Particularly, BOD sensors constructed on the biofilm configuration are discussed regarding performance characteristics like linearity, response time, precision, agreement between BOD values obtained from the biosensors and the conventional 5-days test, as well as toxic resistance to various compounds and operational
Abstract is not available.
To define the early cytogenetic events important in esophageal carcinogenesis, we immortalized normal esophageal epithelial cells by overexpression of human papillomavirus type 16 E6/E7 (HPV16E6/E7) and human telomerase reverse transcriptase (hTERT), and characterized the chromosomal abnormalities serially before and after Cellular immortalizaiton. During crisis. most cells had simple nonclonal ka
Measurement of S-phase fraction by DNA flow cytometry is widely used in the analysis of human tumors. The calculation of fraction of S-phase cells is performed either by means of curve-fitting techniques or by more simple planimetric methods. Estimates by the latter often suffer from subjectivity or poor adaptation to complex DNA histograms. We describe a variant which is based on the rectangular
Phylogenetic analyses were carried out on 23 samples representing 10 cetrarioid taxa from Europe and North America, representing 10 cetrarioid taxa; they were compared in parsimony analyses. The study is focused on ITS sequences of the ribosomal DNA. Intervening sequences, most likely representing group I introns, were found in four taxa. The results from the phylogenetic analysis are congruent wi
