Testosterone is a hormone that plays a key role in carbohydrate, fat, and protein metabolism. Testosterone deficiency is associated with multiple comorbidities, e.g., metabolic syndrome and type 2 diabetes. Despite its importance in many metabolic pathways, the mechanisms by which it controls metabolism are not fully understood. The present study investigated the short-term metabolic changes of ph

Savannas cover a wide climatic gradient across large portions of the Earth’s land surface and are an important component of the terrestrial biosphere. Savannas have been undergoing changes that alter the composition and structure of their vegetation such as the encroachment of woody vegetation and increasing land-use intensity. Monitoring the spatial and temporal dynamics of savanna ecosystem stru

Vapor pressure deficit (VPD) is of great importance to control the land-atmosphere exchange of water and CO2. Here we use in situ observations to assess the performance of monthly VPD calculated from state-of-the-art data sets including CRU, ERA5, and Modern-Era Retrospective analysis for Research and Applications, Version 2 (MERRA2). We investigate trends in VPD at global scale and for different

Som forskare i skärningspunkten mellan teologi och barndomsstudier delar vi upplevelsen av att när vi presenterar vår forskning i olika sammanhang mötas av vad vi tolkar som en okritisk teologisk barnsyn, som inte tar hänsyn till enskilda barns erfarenheter. I den här artikeln undersöker vi hur teologi och teologiska praktiker utmanas av att lyssna till barn som själva deltar i dessa praktiker. ViIn this article we discuss and problematise what we perceive as an uncritical theological view of children. Such a view does not take the experiences of particular children into account but constructs a universal understanding of children and childhood. Here we wish to explore how theology is challenged by listening to children who themselves take part in theological practices. The material we emp

More than a decade ago the WHO Health Promoting Hospitals project was initiated in order to support hospitals towards placing greater emphasis on health promotion and disease prevention, rather than on diagnostic and curative services alone. Twenty hospitals in eleven European countries participated in the European pilot project from 1993 to 1997. Since then, the International Network of Health Pr

Parkinson´s disease (PD) is one of the most common neurological diseases with both motor and non-motor symptoms that can be perceived as difficult to control despite medical treatment. This leads to several consequences in everyday life for example difficulties in activities of daily living (ADL), sometimes already at diagnosis. Therefore, rehabilitation is important to manage the consequences of

Acute myeloid leukemia (AML) is a heterogeneous disease with variable patient responses to therapy. Selinexor, an inhibitor of nuclear export, has shown promising clinical activity for AML. To identify the molecular context for monotherapy sensitivity as well as rational drug combinations, we profile selinexor signaling responses using phosphoproteomics in primary AML patient samples and cell line

The relationships between species abundance or occurrence versus spatial variation in climate are commonly used in species distribution models to forecast future distributions. Under “space-for-time substitution”, the effects of climate variation on species are assumed to be equivalent in both space and time. Two unresolved issues of space-for-time substitution are the time period for species' res

Perennial grain crops could make a valuable addition to sustainable agriculture, potentially even as an alternative to their annual counterparts. The ability of perennials to grow year after year significantly reduces the number of agricultural inputs required, in terms of both planting and weed control, while reduced tillage improves soil health and on-farm biodiversity. Presently, perennial grai

Objective: The clinical significance of a higher BMI on the prognosis of ovarian cancer remains controversial; therefore, a more detailed analysis is demanded. This study investigated the impact of BMI on peritoneum-specific recurrence to clarify the involvement of adipose tissue in the proliferation of cancer cells at sites of peritoneal dissemination. Methods: Among 4,730 patients with malignant

The genetic background of familial, late-onset colorectal cancer (CRC) (i.e., onset > age 50 years) has not been studied as thoroughly as other subgroups of familial CRC, and the proportion of families with a germline genetic predisposition to CRC remains to be defined. To define the contribution of known or suggested CRC predisposition genes to familial late-onset CRC, we analyzed 32 well-establi

Introduction: We evaluated the concordance of the Neurological pupil Index (NPi) with other predictors of outcome after cardiac arrest (CA). Methods: Post hoc analysis of a prospective, international, multicenter study including adult CA patients. Predictors of unfavorable outcome (UO, Cerebral Performance Category of 3–5 at 3 months) included: a) worst NPi ≤ 2; b) presence of discontinuous enceph

Materials with a kagome lattice structure display a wealth of intriguing magnetic properties due to their geometric frustration and intrinsically flat band structure. Recently, topological and superconducting states have also been observed in kagome systems. The kagome lattice may also host a "breathing"mode that leads to charge density wave (CDW) states, if there is strong electron-phonon couplin

Marine sedimentary ikaite is the parent mineral to glendonite, stellate pseudomorphs found throughout the geological record which are most usually composed of calcite. Ikaite is known to be metastable at earth surface temperatures and pressures, readily breaking down to more stable carbonate polymorphs when exposed to warm (ambient) conditions. Yet the process of transformation of ikaite to calcit

Abstract på franskaAnton Nilsson (1887-1989) est l’une des plus célèbres figures du mouvement ouvrier suédois, un militant de premier plan élevé au statut d’icône. Membre du Mouvement des jeunes socialistes dans la ville ouvrière de Malmö, il place une bombe sur le navire Amalthea, qui abritait 73 briseurs de grève anglais, dans le cadre d’un vaste conflit du travail impliquant les dockers des porAnton Nilsson (1887–1989) is one of the most famous people in the Swedish labour movement and a prominent activist with the status of an icon. He was a member of the Young Socialist movement in the working-class city of Malmö, he placed a bomb on the ship Amalthea, which housed 73 English strike breakers, in connection with an extensive dock worker conflict in the Swedish ports. Anton Nilsson was

IntroductionThe child’s best interest has moral foundations in medicine and has existed for decades in the field of paediatrics. Indeed, there are recommendations for the child’s best interests to be a primary consideration in all matters that concern the child. However, there is uncertainty in the literature over how the child’s best interests may be safeguarded within healthcare. AimThe aim of t