Epitopes found on Mucin-1 are differentially expressed on tumour versus normal tissue. Such epitopes have also been shown to have a potential in immunotherapy and tumour detection. The major epitope explored in this context is located within the variable number of tandem repeats. It has however recently been demonstrated that this epitope exists in several sequence variants. The standard sequence

A classical linear programming approach to optimization of flow or transportation in a discrete graph is extended to hybrid systems. The problem is finite-dimensional if the state space is discrete and finite, but becomes infinite-dimensional for a continuous or hybrid state space. It is shown how strict lower bounds on the optimal loss function can be computed by gridding the continuous state spa

We investigated the potential use of Al2O3:C for medical proton dosimetry. Detector crystals coupled to fiber-optic cables were irradiated in proton beams with energies from 10 to 60 MeV. The key finding is that the initial intensity of the optically stimulated luminescence (OSL) signal is energy independent for small detectors (

The mixed-valence dinuclear ruthenium complex [Ru2(bpmp)(-OAc)2]2+ (where bpmp is the phenolate anion of 2,6-bis[bis(2-pyridylmethyl) aminomethyl]-4-methylphenol, H-bpmp) has been studied by UV-Vis-NIR, IR, and EPR spectroscopic and electrochemical techniques. The Ru2II,III complex undergoes reversible one-electron reduction (E1/2 = -0.61 V vs Fc+/0) and oxidation (E1/2 = 0.09 V vs Fc+/0), resulti

I denna bok redovisas ett projekt i Lund (kv. Bollen) vars syfte var att visa att det med tillgänglig teknik och till rimliga kostnader går att bygga bostäder som uppfyller högt ställda krav på ljudkomfort. De uppställda kraven, problembeskrivningar, valda lösningar, kostnadsförändringar samt de utförandetekniska konsekvenserna redovisas detaljerat.

The Rydberg formula is emblematic of atomic spectroscopy. We review here the personal background, research accomplishments, and academic career of its discoverer, Janne Rydberg. Although his formula is often introduced as a generalization of the hydrogenic Balmer formula, Rydberg’s work was independent of Balmer’s, and displayed great ingenuity and a rare ability to recognize hidden patterns in co

The thesis presents the author s research on numerical methods for Com-putational Aeroacoustics and the development of computational tools with direct applicability in industry. The designers in the gas-turbine industry, require accurate methods for predicting the onset and the frequencies of dangerous (pressure) oscillations, like the ones which typically occur in Lean Premixed Pre-vaporized (LPP

The Ax phenotype is an important subgroup of the ABO blood group system. Its inheritance does not always follow Mendelian rules and recent studies suggested that different alleles can result in this phenotype. This suggestion has been explored by cloning and sequencing exons 6 and 7 of the ABO gene and the intervening intron from members of six unrelated families expressing the Ax phenotype. Two f

On 7 December 1975 Indonesian troops invaded the former Portuguese colony of East Timor, which had unilaterally declared itself independent on 28 November the same year. The immediate background to the Indonesian invasion of East Timor was that the old regime in Portugal was overthrown in April 1974, resulting in a decolonisation programme for Portugal's colonies. Immediately after the invasion In

Introduktionsartikel till temanummer om ord och bild i Scandia.

After a long period of stagnation, Syria during the nineteenth century arose to a cultural and social renaissance. One important field of development was education. An article published in Beirut in 1883 sheds important light on this. External impulses were important, but much of the development effort was indigenous. There were significant differences in the level of education between towns and t

The potential and limitations of the Homogeneous Charge Compression Ignition (HCCI) engine concept has been experimentally investigated. The operation range, in terms of usable air/fuel ratio and engine load, and the emission characteristics have been studied. An 1.6 litre single cylinder engine based on a heavy duty six cylinder Volvo, was used for the tests. As follows the experimental work was

This article examines the genetic relationships among 34 MSS suspected of being related because of a peculiar shared reading in John 8:8b-9a: "he wrote on the ground the sins of each..." A quantitative analysis detected several independent families, including new family P members and a dozen MSS forming "family Patmos/M;" this family, in turn, includes the original Patmos family discovered by Silv

Synaptotagmins (Syts) are involved in Ca2+-dependent insulin release. However, which Syt isoform is functional in primary beta-cells remains unknown. We demonstrate by electron microscopy of pancreatic islets, the association of Syt 9 with insulin granules. Silencing of Syt 9 by RNA interference adenovirus in islet cells had no effect on the expression of Syt 5, Syt 7 and Syt 3 isoforms. The latte

It is becoming increasingly clear that conditions experienced during embryonic development can be of major importance for traits subsequent to parturition or hatching. For example, in mammals, offspring from stressed mothers show a variety of changes in behavioural, morphological, and life-history traits. The effects of maternal stress on trait development are believed to be mediated via transfer

This cross-sectional study was done in order to ascertain whether there is a lifelong beneficial effect on bone mineral density (BMD) of early, long-lasting, and intense physical exercise. Forty-eight male ex-weight lifters, mean age 64 years (range 50-79) participated. They had followed a training program of an average of 10 hours/week (range 4-20) for an average of 13 years (range 1-34). They ha