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Early Neolithic Human Bog Finds from Falbygden, Western Sweden : New Isotopic, Osteological and Histological Investigations

Departing from two recently dated finds of human bones in wetlands from the area of Falbygden in western Sweden, this paper describes the finds in detail and sets them in a wider context of depositional practices in the south Scandinavian Early Neolithic. The two finds are both of girls in the age of 15-20 years, and in one of the cases it is probable that she was bound and possibly intentionally

Engineering tyrosine residues into hemoglobin enhances heme reduction, decreases oxidative stress and increases vascular retention of a hemoglobin based blood substitute

Hemoglobin (Hb)-based oxygen carriers (HBOC) are modified extracellular proteins, designed to replace or augment the oxygen-carrying capacity of erythrocytes. However, clinical results have generally been disappointing due to adverse side effects, in part linked to the intrinsic oxidative toxicity of Hb. Previously a redox-active tyrosine residue was engineered into the Hb β subunit (βF41Y) to fac

The Social Cost of Automobility, Cycling and Walking in the European Union

Cost-benefit-analyses (CBA) are widely used to assess transport projects. Comparing various CBA frameworks, this paper concludes that the range of parameters considered in EU transport CBA is limited. A comprehensive list of criteria is presented, and unit costs identified. These are used to calculate the external and private cost of automobility, cycling and walking in the European Union. Results

När slutade reformationen? : Reformation, konfessionalisering och representationen av Martin Luther i svensk bokproduktion under 1500-talet

When did the Reformation end? Reformation, confessionalization and the representation of Martin Luther in Swedish 16th-century printIn the past decades, Swedish scholars have used the concept of the Reformation to refer to a long process of religious change in Sweden between 1527 and 1593. The influence from the term ”the long reformation” used in the Anglo-Saxon world is tangible. Instead, this e

Association between added sugar intake and mortality is nonlinear and dependent on sugar source in 2 Swedish population-based prospective cohorts

Background: Although sugar consumption has been associated with several risk factors for cardiometabolic diseases, evidence for harmful long-term effects is lacking. In addition, most studies have focused on sugar-sweetened beverages (SSBs), not sugar per se. Objective: The aim of this study was to examine the associations between added and free sugar intake, intake of different sugar sources, a

Scrap happens : A case of industrial end-users, maintenance and component remanufacturing outcome

Extended product life and reuse are cornerstones of the circular economy vision. Remanufacturing is one strategy that could be used to facilitate more reuse. Research on remanufacturing often addresses the use phase of a product from the perspective of the remanufacturer, not of the end-user of the product. Results are often described in terms of barriers and drivers, with end-user awareness of an

High titer ethanol production from rice straw via solid-state simultaneous saccharification and fermentation by Mucor indicus at low enzyme loading

High titer ethanol production from rice straw using Mucor indicus fungus was investigated through the solid-state simultaneous saccharification and fermentation (SSSF) process. The straw was pretreated with 0.5 M sodium carbonate solution for 3, 5, and 10 h to improve the efficiency of the process. Effects of the pretreatment on the composition, structural morphology, cellulose crystallinity, swel

Correlated long-range mixed-harmonic fluctuations measured in pp, p+Pb and low-multiplicity Pb+Pb collisions with the ATLAS detector

Correlations of two flow harmonics vn and vm via three- and four-particle cumulants are measured in 13 TeV pp, 5.02 TeV p+Pb, and 2.76 TeV peripheral Pb+Pb collisions with the ATLAS detector at the LHC. The goal is to understand the multi-particle nature of the long-range collective phenomenon in these collision systems. The large non-flow background from dijet production present in the standard c

The mass distribution and gravitational potential of the Milky Way

We present mass models of the Milky Way created to fit observational constraints and to be consistent with expectations from theoretical modelling. The method used to create these models is that demonstrated in our previous study, and we improve on those models by adding gas discs to the potential, considering the effects of allowing the inner slope of the halo density profile to vary, and includi

Suppressed ACTH Is Frequently Unrelated to Autonomous Cortisol Secretion in Patients With Adrenal Incidentalomas

Objective: ACTH is considered a weak marker for autonomous cortisol secretion (ACS) in patients with adrenal incidentalomas (AIs). Our aim was to investigate suppressed basal ACTH as a marker of ACS and to elucidate why this criterion is of limited value. Methods: Basal ACTH and cortisol after overnight dexamethasone suppression test (cortisolONDST) were measured in 198 patients with unilateral AI

Dendritic cell subpopulations in nasopharyngeal cancer

Nasopharyngeal cancer (NPC) is associated with Epstein-Barr virus (EBV) and EBV antigen may be utilized for therapeutic purposes, including targeting of dendritic cells (DCs). Although DCs may be present in NPC, the information is limited and not up-to-date with current knowledge on DC subsets. In the present study, biopsies from untreated NPC were obtained and subjected to multicolor flow-cytomet

Apolipoprotein M induces inhibition of inflammatory responses via the S1PR1 and DHCR24 pathways

© 2019 Spandidos Publications. All rights reserved. Apolipoprotein M (ApoM) is a type of apolipoprotein. It is well known that high-density lipoprotein (HDL) decreases inflammatory responses via the apoM-sphingosine-1-phosphate (S1P) pathway. The present study further investigated the importance of ApoM in the inhibitory effects of HDL on inflammation. Mice with an apoM gene deficiency (apoM-/-) w

Setting her even straighter : Further notes on the osteology and necrodynamics of the Mesolithic burial from Barum, Scania, Sweden

This paper communicates the results of a reassessment of the original burial position of the Barum burial, Scania, Sweden, dated to c. 8,700 years ago. Based on a thorough analysis of the photographs from Folke Hansen’s excavation, it is concluded that the body was placed in an upright sitting position. The notion that the body was leaning backwards is based on a faulty interpretation of the origi