Search results

Filter

Filetype

Your search for "*" yielded 553593 hits

Ethylcellulose oleogel as a prolonged release delivery system for probiotics. Development and validation of a cold-mixing method

Ethylcellulose thickened oil (EC oleogels) has a significant retarding effect on lipolysis and may be used for controlled-release formulations. However, the high temperature (above 150 °C) used during the gel-forming process becomes an obvious limitation that hinders the application of EC oleogels to temperature-sensitive active ingredients. A cold-mixing procedure that could allow for an encapsul

Science diplomacy : A global research field? Findings from a bibliometric analysis of the science diplomacy scholarship of the past twenty years

Science diplomacy is a unique research field that is driven and shaped by scholars and practitioners alike. This study examines whether and how recent trends in the broader science diplomacy discourse have impacted scholarship on the topic. First, it examines whether the pertinent scholarship is as international in outlook as practitioners have made science diplomacy out to be. Second, the study i

Tunable Elasto-Viscoplastic Properties of Polymer Blends for 3D Printing Applications

Post-extrusion flow dynamics of soft matter are governed by their elasto-viscoplastic (EVP) rheological properties, which influence filament stability, die swelling, and shape fidelity in extrusion-based 3D printing. Achieving precision and control in printed structures requires optimizing yield stress, viscoelasticity, and extrusion pressure to minimize excessive die swelling and material spreadi

Numerical studies of strong protein interactions

Protein–protein interactions are fundamental to biological functions as well as the design of new functional food products and biomedicines. However, they can be challenging to computationally quantify due to strong forces and sensitivity to pronounced solution conditions. This thesis combines computational methods with Monte Carlo simulations to investigate strong protein interactions in diverse

Integrating ML Approaches for Photodetectors

Optical sensor technologies are central to the advancement of Internet of Things (IoT) ecosystems and smart systems. Among these, photodetectors—a key subset of optical sensors—find extensive applications in areas such as smart sensing, home automation, autonomous vehicles, wearable electronics, and AI-driven platforms. The demand for highly sensitive, cost-effective, flexible, and lightweight pho

Genome-scale CRISPR screens identify PTGES3 as a direct modulator of androgen receptor function in advanced prostate cancer

The androgen receptor (AR) is a critical driver of prostate cancer (PCa). Here, to study regulators of AR protein levels and oncogenic activity, we developed a live-cell quantitative endogenous AR fluorescent reporter. Leveraging this AR reporter, we performed genome-scale CRISPRi flow cytometry sorting screens to systematically identify genes that modulate AR protein levels. We identified and val

Exploring interface tension as a tool to control the morphology of binary organic semiconductor nanoparticles prepared by nanoprecipitation

The ability to control the morphology of organic semiconductor nanoparticles is of paramount importance for applications in organic photovoltaics, photocatalysis, and photo-triggered biological applications. In this paper, we demonstrate that nanoprecipitation is a powerful technique to provide a variety of morphologies in binary blends of organic semiconductors. By investigating seven different d

First mirror stability at the MAX IV soft x-ray beamlines

Horizontal drift of the beam on the MAX IV soft x-ray beamlines was observed with a 1-2 hour settling time and strong dependence on the undulator power setting. A water cooled, suspended electrode was designed and is shown to reduce the horizontal beam drift on three MAX IV soft x-ray beamlines to acceptable operational levels.

Multiple System Atrophy Without Dysautonomia : An Autopsy-Confirmed Study

BACKGROUND AND OBJECTIVES: Multiple system atrophy (MSA) is a neurodegenerative disorder characterized by 3 core symptom complexes: parkinsonism, cerebellar syndrome, and dysautonomia. Recent Movement Disorder Society (MDS) criteria allow for the clinical diagnosis of MSA based solely on motor symptoms, without requiring dysautonomia. This study aimed to evaluate the frequency and disease trajecto

Journal Club : Endovascular Therapy for Patients With Low NIHSS Scores and Large Vessel Occlusion in the 6- to 24-Hour Window

Endovascular therapy (EVT) has proven benefit for patients with anterior circulation large vessel occlusion (LVO) strokes with moderate-to-severe deficits, but its value in patients presenting 6-24 hours after onset with mild symptoms (NIH Stroke Scale score ≤5) remains unclear. This journal club article examines a retrospective analysis of CLEAR registry data comparing EVT with medical management

Environmental dynamics recorded at Dupljaja loess section (southeastern Carpathian Basin, northern Serbia)

The Dupljaja loess-palaeosol sequence in the southeasternmost sector of the Banat Loess Plateau, Serbia, is of significant palaeoenvironmental importance. Situated within the southeastern Carpathian (Middle Danube) Basin, it provides valuable insights into the climatic evolution during the last glacial period and role of the southeastern Carpathians as a potential migration corridor for early huma

Salutogenesis : A Compass for Health Promotion

In this chapter, the salutogenic framework is applied as a theoretical foundation for health promotion. Health promotion and salutogenesis are intertwined. In this chapter, they are therefore compared using their respective value sets in the search for coherent interpretations. Some core concepts of salutogenesis and health promotion, such as health, wellbeing, quality of life and human rights are

Fractional Flow Reserve to Guide Revascularization in Patients With Coronary Artery Disease Undergoing TAVR

Background The prognostic value of fractional flow reserve (FFR) in assessing coronary stenosis before transcatheter aortic valve replacement (TAVR) is unclear. Objectives The aim of this study was to evaluate cardiovascular risks associated with significant and nonsignificant FFR values of coronary stenosis prior to TAVR. Methods Patients were enrolled from the NOTION-3 (Nordic Aortic Valve Inter

Interference between One- and Two-Electron Channels in Resonant Inelastic X-Ray Scattering

Interference between scattering channels is observed in resonant inelastic x-ray scattering (RIXS) at the Ne K threshold. Final states with |2p-1np⟩ as the main configuration are populated via |1s-1n′p⟩ resonances, where large-amplitude one-electron (n′=n) channels interfere with small-amplitude two-electron (n′≠n) channels. The interference is manifested in an asymmetric line profile where the tw

Efficacy of the Web-Based Swedish Individualized Active Communication Education (I-ACE) Program in First-Time Hearing Aid Users : Randomized Controlled Trial

Background: Hearing loss is estimated to affect more than 20% of the global population. Hearing aid fitting is a common intervention in audiological rehabilitation; however, there are still those who struggle with remaining communication difficulties that require additional intervention. The group rehabilitation program Active Communication Education (ACE) has been shown to be an effective alterna

Hur cancer och dess följder påverkar aktivitet och delaktighet bland vuxna.

Bakgrund: Cancer ökar globalt och trots att fler överlever så lever fortfarande många med kvarstående symtom som påverkar vardagen. Aktivitet och delaktighets positiva inverkan på människans välbefinnande är välbeforskat. Däremot finns det lite forskning kring hur cancer påverkar människans aktivitet och delaktighet. Syfte: Syftet är att sammanställa hur tidigare forskning beskriver hur cancer ochBackground: Cancer is increasing globally and although more people are surviving, many still live with residual symptoms that affect everyday life. Activity and particapations impact on peoples well-being are well studied. However there is little research on how cancer affects activity and participation. Purpose: The aim of this study was to describe how cancer and its consequences affect activi

“Framtiden känns ljusare” - En kvalitativ intervjustudie om aktivitetsbalans hos studerande på allmän folkhögskolelinje i Skåne.

Bakgrund: Folkhögskolan är ett unikt nordiskt fenomen med stor möjlighet till anpassning av studierna. Studier i sig påverkar aktivitetsbalansen, vilken är upplevelsen av balans mellan måsten och meningsfulla aktiviteter. Folkhögskolestuderande är en underbeforskad grupp framförallt inom arbetsterapi. För att beskriva komplexiteten i aktivitetsbalans används aktivitetsvetenskapliga modeller. SyfteBackground: Folk high schools are a uniquely Nordic phenomenon with individualized pedagogy. Studying affects occupational balance, which is the experience of balance between tasks and meaningful activities. Folk high school students as a group are not widely researched, particularly in combination with occupational therapy. To describe the complexity of occupational balance, models linked to occu

Managing Migration, Evading Responsibility? - Extraterritorial Jurisdiction and Externalisation in the EU Migration Regime

With the adoption of the New Pact on Migration and Asylum, the European Union (EU) and its Member States are encouraged to cooperate with third States through informal agreements, notably in the form of Memoranda of Understanding (MoUs). These arrangements form a central component of the EU’s externalisation strategy, shifting its borders outwards and thereby limiting the circumstances under which

Corporate Criminal Liability for International Core Crimes – A Comparative Analysis of the French and Swiss Regulations

This thesis examines the extent to which the French and Swiss models of corporate criminal liability may inform the development of proposals to extend the jurisdiction of the International Criminal Court (ICC) to encompass legal persons. The study employs a combination of doctrinal and comparative legal methodology, with particular emphasis on the legal models through which criminal liability may