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Satellite-based assessment of upstream regulation impacts on downstream reservoir dynamics and agricultural activity between the Turkey and Syria

Water has long been a strategic resource in the semi-arid landscapes of Mesopotamia, a region spanning Turkey, Syria, and Iraq, where the Tigris and Euphrates rivers form the lifeline of societies. As water scarcity intensifies due to a combination of climatic stressors and anthropogenic pressures, the governance of transboundary rivers has become critical for ensuring health, food security, and r

Miljöorganisationers talerätt med stöd av Århuskonventionen : En analys av implementeringen i svensk rätt och dess konsekvenser för enskilda

Artikeln analyserar hur Århuskonventionens tredje pelare om allmänhetens tillgång till rättslig prövning har implementerats i svensk rätt och därefter utvecklats genom EU‑domstolens praxis och svenska domstolsavgöranden. Analysen exemplifierar genom att ta sin utgångspunkt i miljöorganisationers talerätt i skogsbruksfrågor. Lagstiftarens ursprungliga intentioner vid införlivandet (särskilt Ds 2004

Favourable outcome in a subset of ultra-severe traumatic brain injury patients - a single-centre retrospective study

Introduction: Ultra-severe traumatic brain injury (us-TBI), defined as Glasgow Coma Scale score (GCS) of five-three, is associated with high mortality and severe morbidity amongst survivors. However, in selected patients a favourable recovery may still be achieved. Research question: We aimed to characterise what clinical parameters can be used as prognosticators in us-TBI patients. Material and m

An integrated techno-economic-environmental-policy assessment of supercritical biodiesel production : pathway to competitiveness

Despite its promise, biodiesel production via the supercritical methanol (SCM) process has stalled due to limited understanding of interactions among key operating parameters and process-modeling gaps, resulting in contradictory techno-economic (TEA) and life-cycle carbon footprint assessments. In the present study, we integrate experimental optimization with techno-economic, carbon footprint, and

Pelvic floor symptoms and quality of life 1 year postpartum in Swedish primiparous women—A follow-up of a randomized controlled trial

Introduction: Long-term pelvic floor symptoms after childbirth may impair women's quality of life. The aim of this study was to assess the prevalence of self-reported pelvic floor symptoms 1 year postpartum in primiparous women by degree of perineal tear, with a focus on minor and major second-degree tears, and their association with quality of life. Material and Methods: This prospective cohort s

Disentangling Vibronic Coupling and Conformational Disorder in Flexible NDI–T2 Donor–Acceptor Co-Oligomers

The unusually broad and intense visible (Vis) absorption band observed in naphthalenediimide–bithiophene (NDI-T2) co-polymers reflects complex electronic and vibronic interactions between donor and acceptor units. While the charge-transfer character arising from electronic coupling across the moieties likely contributes to the red-shifted absorption, the pronounced spectral broadness may also orig

Indirect Striatal Projection Neurons Drive a D2 Receptor-Dependent Pathway to Dyskinesia and Dystonia

Background: L-DOPA-induced dyskinesia is attributed to opposite activity changes mediated by D1 and D2 dopamine receptors in the two striatal output pathways. Whereas the causal role of direct-pathway D1 receptors is well established, the specific involvement of indirect-pathway D2 receptors in dopaminergic dyskinesias has remained elusive. Objectives: We used conditional knockout approaches in mi

Tannin Phytocomplex Improves IBS-D Symptoms and Gut-Brain Markers : Prospective Pilot Study

Diarrhea-predominant irritable bowel syndrome (IBS-D) is a multifactorial disorder involving gut-brain axis dysregulation, altered barrier integrity, microbial imbalance, and stress-related mechanisms, with limited nutritional strategies targeting these pathways. Tannin-rich extracts may exert barrier-protective, microbiota-modulating, and stress-related effects. In a prospective before-after pilo

Direct neuronal reprogramming : emerging therapeutic strategies for neurodegenerative disorders

Background: Treatment of brain injuries and neurodegenerative disorders is a critical challenge due to poor regenerative capabilities of the central nervous system. The current therapeutic strategies are primarily focussed on treating the symptoms than addressing the core issue of loss of neurons. Despite advances in stem cell therapies and surgical alternatives, they are not always successful due

Effects of race distance and probiotics intervention on kidney, muscle, and gut injury and inflammation biomarker responses during running

Introduction: Prolonged intense physical activity, such as long-distance running, may lead to systemic inflammation and cause organ injury, particularly to the kidneys. This study aimed to assess the impact of trail race running on kidney and muscle injury and gut inflammation biomarkers, and the potential mitigating effects of Lactiplantibacillus plantarum 299v (Lp299v) supplementation. Methods:

Finite element analysis of harmonic structured materials

Utvecklingen av de strukturella egenskaperna hos metaller är kritisk för en effektiv användning av naturtillgångar och en cirkulär ekonomi. På senaste tid har en ny klass material med imponerande strukturella egenskaper visats sig vara väldigt intressanta, nämligen harmoniskt strukturerade material. I den här rapporten analyseras en simulering av ett dragprov för att synliggöra de essentiella mekaThe improvement of the structural properties in crystalline materials is of critical importance for an efficient use of natural resources and a circular economy. It has been found that these properties can be altered through severe plastic deformation. Bimodal harmonic structured (bHS) materials is a new class of materials having specified topological arrangement of coarse- and ultra-fine grains.

Utvärdering av ramverk för webbaserade användargränssnitt med fokus på tillämpningar inom finita elementberäkningar

I detta arbete undersöks möjligheten att införa ett webbaserat alternativ till den nuvarande Qt-baserade gränssnittsdelen i kursen VSMN20, Programutveckling för tekniska tillämpningar, vid Lunds Tekniska Högskola. Bakgrunden är en tydlig rörelse på programvarumarknaden mot webbaserade och molnbaserade lösningar, och frågan om hur man skulle kunna få in den förändringen i en kurs där studenter arbeThis study evaluates three Python-based frameworks for developing web applications for finite element analysis: Dash, Streamlit, and NiceGUI. The evaluation focused on interactivity, usability, and suitability for inclusion in a course at LTH about software development for technical applications. To compare the frameworks, the final course project was recreated in each of them while keeping the un

Application of the International Bladder Cancer Group prediction model for recurrence-free survival on a national cohort of primary intermediate risk non-muscle invasive bladder cancer

The International Bladder Cancer Group (IBCG) has proposed a prognostic model for intermediate risk (IR) non-muscle invasive bladder cancer (NMIBC) for clinical decision-making. We applied the IBCG IR model in a population-based Swedish setting in patients with primary IR NMIBC diagnosed 2013-2014 in BladderBaSe 2.0. Patients were stratified into low-risk (unifocal and tumour size < 3 cm) and inte

A user-friendly goniometer-compatible fixed-target platform for macromolecular crystallography at synchrotrons

Fixed-target platforms provide convenient support for microcrystals during serial X-ray crystallography studies using synchrotron radiation. Here, we describe a simple user-friendly 3D-printed support where the crystals are sandwiched between two layers of thin X-ray-transparent membrane resulting in very low scattering background. The platform is compatible with magnetic mounting onto the standar