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Variable risk preferences in new firm growth and survival

We outline and test a decision-making theory of new venture growth and survival. Building upon research in entrepreneurship and decision making under risk, we hypothesize that entrepreneurs’ attention to survival and aspiration reference points changes based on venture age (experience-based learning), size (differences in decision complexity), and performance decision domain. Examining a panel of We outline and test a decision-making theory of new venture growth and survival. Building upon research in entrepreneurship and decision making under risk, we hypothesize that entrepreneurs' attention to survival and aspiration reference points changes based on venture age (experience-based learning), size (differences in decision complexity), and performance decision domain. Examining a panel of

Human anaplastic thyroid carcinoma cells are sensitive to NK cell-mediated lysis via ULBP2/5/6 and chemoattract NK cells

PURPOSE: Anaplastic thyroid carcinoma (ATC) is one of the most aggressive forms of cancer with no curative therapies available. To date, strategies to target ATC by immunotherapy have not been evaluated. We investigated whether ATC would be a suitable target for natural killer (NK) cell-based immunotherapy.EXPERIMENTAL DESIGN: We first established seven new cell lines from ATC tumors, three from p

Harmonic morphisms from five-dimensional Lie groups

We consider 5-dimensional Lie groups equipped with a left-invariant Riemannian metric. On such groups we construct left-invariant conformal foliations with minimal leaves of codimension 2. These foliations produce complex-valued harmonic morphisms locally defined on the Lie group.

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The book is a collection of the articles the author has published between 2003-2015, in Romanian or English, in various academic journals. Some of them are concerned with the dramaturgy of Mihail Sebastian (Jocul de-a vacanța), of Marin Sorescu (Paracliserul), the translations and versifing of the Psalms by Dosoftei, Derrida's deconstruction philosophy as opposed to Saussure's structuralism, teach

Betydelsen av fysiska och psykosociala riskfaktorer för sjukdom/besvär i muskler och leder - En uppföljningsstudie av kvinnor inom vård och skola

Vi har upprättat en kohort med 1591 kvinnor från fem vanliga yrken: Operationssköterskor (Op), anestesisköterskor (Ane), undersköterskor på operation (Usk), biomedicinska analytiker som gör ultraljudsundersökningar (BMA) samt lärarinnor (Lär). Enkät har skickats ut vid baseline och i genomsnitt ca 28 månader därefter. Data från uppföljningen är inte analyserade ännu, varför rapporten enbart omfatt

Sex and age related changes in the locomotor activity and phototactic behaviors of two closely related species of Camponotus ants.

A virgin ant queen has only one opportunity in her lifetime to realize her reproductive fitness when she leaves her nest for a mating flight. After successful mating she sheds her wings, excavates a nest and starts laying eggs to initiate her own colony. Here we report the results of our study on two related species of Camponotus ants - day active Camponotus paria and night active Camponotus compr

Matching authority and VGI road networks using an extended node-based matching algorithm

The amount of volunteered geographic information (VGI) has increased over the past decade, and several studies have been conducted to evaluate the quality of VGI data. In this study, we evaluate the completeness of the road network in the VGI data set OpenStreetMap (OSM). The evaluation is based on an accurate and efficient network-matching algorithm. The study begins with a comparison of the two

Cost effectiveness of pomalidomide in patients with relapsed and refractory multiple myeloma in Sweden

Background: Multiple myeloma (MM) patients who have progressed following treatment with both bortezomib and lenalidomide have a poor prognosis. In this late stage, other effective alternatives are limited, and patients in Sweden are often left with best supportive care. Pomalidomide is a new anti-angiogenic and immunomodulatory drug for the treatment of MM. Our objective was to evaluate the cost e

VEGFR2 pY949 signalling regulates adherens junction integrity and metastatic spread

The specific role of VEGFA-induced permeability and vascular leakage in physiology and pathology has remained unclear. Here we show that VEGFA-induced vascular leakage depends on signalling initiated via the VEGFR2 phosphosite Y949, regulating dynamic c-Src and VE-cadherin phosphorylation. Abolished Y949 signalling in the mouse mutant Vegfr2(Y949F/Y949F) leads to VEGFA-resistant endothelial adhere

Fältval hos höstrastande och övervintrande gäss i sydvästra sverige 19 77/1978-2011/2012

Field choice was recorded during counts of geese in South-west Scania, South Sweden in autumn (October and November) and in winter (January), 1977/1978-2011/2012. Sugar beet spill was the most important field type in autumn and during the last ten years also in winter. Bean Geese Anserfabalis used this food source when the study started while Canada Geese Branta canadensis, Greylag Geese Anser ans

Are Stem Cell-Based Therapies for Parkinson's Disease Ready for the Clinic in 2016?

Recent news of an impending clinical cell transplantation trial in Parkinson's disease using parthenogenetic stem cells as a source of donor tissue have raised hopes in the patient community and sparked discussion in the research community. Based on discussions held by a global collaborative initiative on translation of stem cell therapy in Parkinson's disease, we have identified a set of key ques

Gender-related differences in urothelial carcinoma of the bladder : a population-based study from the Swedish National Registry of Urinary Bladder Cancer

OBJECTIVE: The aim of this investigation was to describe tumour characteristics, treatments and survival in patients with urinary bladder cancer (UBC) in a national population-based cohort, with special reference to gender-related differences.MATERIAL AND METHODS: All primary UBC patients with urothelial pathology reported to the Swedish National Registry of Urinary Bladder Cancer (SNRUBC) from 19

Energy-Efficient Fault Tolerance in Chip Multiprocessors Using Critical Value Forwarding

Relentless CMOS scaling coupled with lower design tolerances is making ICs increasingly susceptible to wear-out related permanent faults and transient faults, necessitating on-chip fault tolerance in future chip microprocessors (CMPs). In this paper we introduce a new energy-efficient fault-tolerant CMP architecture known as Redundant Execution using Critical Value Forwarding (RECVF). RECVF is bas

Gender-specific incidence of autoimmune diseases from national registers

BACKGROUND: It is widely believed that autoimmune diseases affect predominantly in women, but the available evidence came from case control study with potential selection and recall bias. We aimed to examine the gender-specific incidence of autoimmune diseases by using national wide registers in Sweden.METHODS: Swedish Hospital Discharge Register and Outpatient Register were used to identify a set

Conceptual Thermodynamic Cycle and Aerodynamic Gas Turbine Design - on an Oxy-fuel Combined Cycle

The world is today facing a serious problem with global warming, which is heading towards an appallingly high temperature level. The greater part of the overall climate science community agree that global warming is caused by the greenhouse effect, which depends largely on emitted CO2 emissions from the combustion of fossil fuel. The agreement at the COP 21 climate meeting in Paris (December 2015)The world is today facing a serious problem with global warming, which is heading towards an appallingly high temperature level. The greater part of the overall climate science community agree that global warming is caused by the greenhouse effect, which depends largely on emitted CO2 emissions from the combustion of fossil fuel. The agreement at the COP 21 climate meeting in Paris (December 2015)