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130 år av brokigt folkliv

Malmö fick landets första folkpark redan för 130 år sedan. Idag, på parkens födelsedag, reflekterar tre kulturgeografer över anläggningens historia och dess roll i dåtid, nutid och framtid.

Immune response and gut microbiota of mice on a diet mimicking eating habits of elderly with risk of malnutrition development

The number of elderlies is increasing but prevalence of malnutrition has been reported. The aim of the study was to determine the significance of short-term nutritional deficiencies in mice. Immune status was assessed through flow cytometry of leucocytes in Peyer’s patches (PP) and mesenteric lymph nodes (MLN), and intestinal microbiota was evaluated by terminal restriction fragment length polymor

Validation of factor VIII activity for monitoring standard and extended half-life products and correlation to thrombin generation assays

Introduction: Monitoring replacement therapy with standard and extended half-life (EHL) products is challenging, since one-stage assay (OSA) and chromogenic substrate assay (CSA) results may differ significantly. Recent recommendations include local validation of each new product with recovery within 20–30%, depending on activity level. Aim: To validate factor VIII (FVIII) activity for monitoring

Skyddszoner i jordbruket – betalt för resultat?

Många lantbrukare utför frivilliga åtgärder för att gynna miljön. Som kompensation för kostnader och inkomstbortfall får lantbrukarna en miljöersättning. Ersättningen är åtgärdsbaserad, vilket innebär att dess storlek beror på vilken typ av åtgärd det handlar om och dess omfattning. Denna studie undersöker effekten av att istället göra ersättningar resultatbaserade, det vill säga basera dem på hur

Identification of a serum biomarker signature associated with metastatic prostate cancer

Purpose: Improved early diagnosis and determination of aggressiveness of prostate cancer (PC) is important to select suitable treatment options and to decrease over-treatment. The conventional marker is total prostate specific antigen (PSA) levels in blood, but lacks specificity and ability to accurately discriminate indolent from aggressive disease. Experimental design: In this study, we sought t

Rapid diagnostic testing for SARS-CoV-2 : Validation and comparison of three point-of-care antibody tests

With the emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a need for diagnostic tests has surfaced. Point-of-care (POC) antibody tests can detect immunoglobulin (Ig) G and M against SARS-CoV-2 in serum, plasma, or whole blood and give results within 15 min. Validation of the performance of such tests is needed if they are to be used in clinical practice. In this study, we

A Novel Joint Points and Silhouette-Based Method to Estimate 3D Human Pose and Shape

This paper presents a novel method for 3D human pose and shape estimation from images with sparse views, using joint points and silhouettes, based on a parametric model. Firstly, the parametric model is fitted to the joint points estimated by deep learning-based human pose estimation. Then, we extract the correspondence between the parametric model of pose fitting and silhouettes in 2D and 3D spac

A novel delivery system for supraglottic atomization allows increased lung deposition rates of pulmonary surfactant in newborn piglets

Background: Earlier attempts to deliver effective lung doses of surfactant by aerosolization were unsuccessful, mostly because of technical shortcomings. We aimed at quantifying the lung deposition of poractant alfa with a new supraglottic delivery system for surfactant atomization in an experimental neonatal model. Methods: The method involved six sedated 1-day-old piglets lying in the lateral de

Sex differences in life history, behavior, and physiology along a slow-fast continuum : a meta-analysis

The pace-of-life syndrome (POLS) hypothesis predicts that behavior and physiology covary with life history. Evidence for such covariation is contradictory, possibly because systematic sources of variation (e.g. sex) have been neglected. Sexes often experience different selection pressures leading to sex-specific allocation between reproduction and self-maintenance, facilitating divergence in life-

Hydrogeophysical methods and hydrogeological models : basis for groundwater sustainable management in Valle Alto (Bolivia)

In Bolivia climate change and anthropogenic activities such as extensive agriculture, industries and urbanization have increased the groundwater demand and extraction, which is leading to severe stress on groundwater resources in several regions of Bolivia. This research aims to present an overview of different geophysical surveys performed in Valle Alto (central Bolivia), in particular in the Pun

Textile Contact Dermatitis : How Fabrics Can Induce Dermatitis

Purpose of the review: Textile dermatitis can sometimes be difficult to diagnose due to the fact that it is difficult to clinically suspect, and when allergic, patch test correctly and advice the patient as to what garments to avoid. Recent findings: The textile fibres as such are rarely the causative agent. Allergic contact dermatitis due to textiles is primarily caused by substances that are use

Contradictions in care: Ward nurses’ experiences of work and management in the Swedish public sector

In Sweden, austerity politics and market reforms have resulted in a renegotiation of working conditions negatively impacting female-dominated public sector- and welfare state workers. A growing body of research locates the harshening conditions of nurses in a context of colliding logics between professions and professional authority, the specificities of interpersonal work, and public sector restrIn Sweden, austerity politics and market reforms have resulted in a renegotiation of working conditions negatively impacting female-dominated public sector- and welfare state workers. A growing body of research locates the harshening conditions of nurses in a context of colliding logics between professions and professional authority, the specificities of interpersonal work, and public sector restr

Convergence analysis of the nonoverlapping Robin-Robin method for nonlinear elliptic equations

We prove convergence for the nonoverlapping Robin-Robin method applied to nonlinear elliptic equations with a p-structure, including degenerate diffusion equations governed by the p-Laplacian. This nonoverlapping domain decomposition is commonly encountered when discretizing elliptic equations, as it enables the usage of parallel and distributed hardware. Convergence has been derived in various li

Preexisting Somatic Mutations of Estrogen Receptor Alpha (ESR1) in Early-Stage Primary Breast Cancer

More than three-quarters of primary breast cancers are positive for estrogen receptor alpha (ER; encoded by the gene ESR1), the most important factor for directing anti-estrogenic endocrine therapy (ET). Recently, mutations in ESR1 were identified as acquired mechanisms of resistance to ET, found in 12% to 55% of metastatic breast cancers treated previously with ET. We analyzed 3217 population-bas

Motion sickness diagnostic criteria : Consensus document of the classification committee of the Bárány society

We present diagnostic criteria for motion sickness, visually induced motion sickness (VIMS), motion sickness disorder (MSD), and VIMS disorder (VIMSD) to be included in the International Classification of Vestibular Disorders. Motion sickness and VIMS are normal physiological responses that can be elicited in almost all people, but susceptibility and severity can be high enough for the response to

Jesus

En historievetenskaplig analys av Jesu liv och lära.