Complement activation occurs during inflammatory joint diseases such as rheumatoid arthritis (RA) and is thought to contribute to the chronic inflammation observed within the joints. Previous studies have shown that certain cartilage components of the small leucine-rich repeat protein (SLRP)-family regulate complement activity, thereby possibly contributing to disease progression. The aim of this

The Intermediate Data Structure (IDS) provides a common structure for storing and sharing historical demographic data. The structure also facilitates the construction of different open-access software to extract information from these tables and construct new variables. The article Using the Intermediate Data Structure (IDS) to Construct Files for Analysis (Quaranta 2015) presented a series of con

This study examines the influence of vortex core precession on flame flashback of swirl-stabilised hydrogen flames. Theoretical considerations suggest that the angular velocity of a swirling flow is reduced as vortex precession causes it to acquire an eccentric motion around the central axis of the burner. The eccentric motion of the vortex generates a secondary flow, which is thought to reduce th

This article presents results from 23 structured interviews focused on creative meetings (a crucial part of the definition being that something new is created in the meeting, through interaction between people). The interviewees represented many different fields of industry and academia, and together many hundred years of experience of meetings. Six main perspectives pertaining to creative process

Biochemical reactions powered by ATP hydrolysis are fundamental for the movement of molecules and cellular structures. One such reaction is the encapsidation of the double-stranded DNA (dsDNA) genome of an icosahedrally symmetric virus into a preformed procapsid with the help of a genome-translocating NTPase. Such NTPases have been characterized in detail from both RNA and tailed DNA viruses. We p

Objectives - In patients with large middle cerebral artery (MCA) infarcts, maximum brain swelling leading to cerebral herniation and death usually occurs 25 days after onset of stroke. The study aimed at exploring the pattern of compounds related to cerebral energy metabolism in infarcted brain tissue. Methods - Forty-four patients with malignant MCA infarcts were included after decision to perfor

The PreSPEC setup for high-resolution 'gamma-ray spectroscopy using radioactive ion beams was employed for experimental campaigns in 2012 and 2014. The setup consisted of the state of the art Advanced GAmma Tracking Array (AGATA) and the High Energy gamma cleteCTOR (HECTOR+) positioned around a secondary target at the final focal plane of the GSI FRagment Separator (FRS) to perform in-beam gamma-r

Paracetamol is the most commonly used over-the-counter drug in pregnancy. It is generally considered to be safe, but prolonged antenatal exposure has been associated with offspring short- and long-term morbidity. Our aim was to describe the pattern of paracetamol use with a focus on frequent ingestion (more than once a week), 3months before and in early pregnancy. In this cohort, 8650 pregnant wom

Smoking, diabetes, male sex, hypercholesterolaemia and hypertension are well-established risk factors for the development of coronary artery disease (CAD). However, less is known about their role in influencing the outcome in the event of an acute coronary syndrome (ACS). The aim of this study was to determine if these risk factors are associated specifically with acute myocardial infarction (MI)

Background In many scientific domains, it is becoming increasingly common to collect high-dimensional data sets, often with an exploratory aim, to generate new and relevant hypotheses. The exploratory perspective often makes statistically guided visualization methods, such as Principal Component Analysis (PCA), the methods of choice. However, the clarity of the obtained visualizations, and thereby

Abstract in UndeterminedA laboratory implementation of a two-phase travelling wave induction heating setup is described. The focus is the development of a versatile power control system for multi-coil experiments and parameter studies.The drive system features high temporal accuracy, full real-time controllability, and integrated measurement technology, analyzed step wise. The performance was test

Gas in scattering media absorption spectroscopy (GASMAS) has been extensively studied and applied during recent years in, e.g., food packaging, human sinus monitoring, gas diffusion studies, and pharmaceutical tablet characterization. The focus has been on the evaluation of the gas absorption pathlength in porous media, which a priori is unknown due to heavy light scattering. In this paper, three

Single-shaft gas turbine and its cycles are sensitive to frequency drops and, therefore, sudden change loads or large frequency dips might affect their stability. This phenomenon is related to the reduction of the air mass flow passing through the machine during the frequency dips, which might lead to an interaction between governor and temperature control loop. In this paper, the performance of t

Abstract in UndeterminedIn this article we study the evolution of marriage seasonality in relation to economic change, particularly connected to changes in labour supply and work intensity of the kind implied by the ‘industrious revolution’. The focus is on southern Sweden in 1685–1894, which was a period of agricultural transformation and early industrialization, when we would expect to see an in

P>Background: This study reports the clinical and immunological state of patients 3 years after a 6-year period of Xolair treatment for severe allergic asthma. Methods: The patient's cat allergen sensitivity, measured as CD-sens, IgE and IgE- and IgG4 antibodies, was analysed and compared with asthma severity evaluated from FEV1 and a questionnaire. Results: Three years after treatment with Xolair

Land use intensification is associated with loss of biodiversity and altered ecosystem functioning. Until now most studies on the relationship between biodiversity and ecosystem functioning focused on random loss of species, while loss of rare species that usually are the first to disappear received less attention. Here we test if the effect of rare microbial species loss on plant productivity dep