Search results

Filter

Filetype

Your search for "*" yielded 531595 hits

Impact of hip arthroplasty registers on orthopaedic practice and perspectives for the future

□ Total hip arthroplasty (THA) registers are established in several countries to collect data aiming to improve the results after THA. Monitoring of adverse outcomes after THA has focused mainly on revision surgery, but patientreported outcomes have also been investigated. □ Several surgery-related factors influencing the survival of the THA have been thoroughly investigated and have changed clini

Radium isotopes distribution and submarine groundwater discharge in the Bohai Sea

In order to characterize the radium distribution and submarine groundwater discharge (SGD) in the Bohai Sea area, the three isotopes 223Ra, 224Ra and 228Ra in different water bodies were measured in a 4-year period with the radium-delayed coincidence counting (RaDeCC) system. The results indicated that radium activities take an order of groundwater > coastal seawater > river water > central seawat

Proteomic signatures of brain regions affected by tau pathology in early and late stages of Alzheimer's disease

Background: Alzheimer's disease (AD) is the most common neurodegenerative disorder. Depositions of amyloid β peptide (Aβ) and tau protein are among the major pathological hallmarks of AD. Aβ and tau burden follows predictable spatial patterns during the progression of AD. Nevertheless, it remains obscure why certain brain regions are more vulnerable than others; to investigate this and dysregulate

Smart and sustainable cities? : pipedreams, practicalities and possibilities

Smart cities promise to generate economic, social and environmental value through the seamless connection of urban services and infrastructure by digital technologies (Hollands 2008, Viitanen and Kingston 2014), but there is scant evidence concerning their ability to enhance social well-being, build just and equitable communities, reduce resource consumption and waste generation, improve environme

Classification of dark states in multilevel dissipative systems

Dark states are eigenstates or steady states of a system that are decoupled from the radiation. Their use, along with associated techniques such as stimulated Raman adiabatic passage, has extended from atomic physics, where it is an essential cooling mechanism, to more recent versions in the condensed phase where it can increase the coherence times of qubits. These states are often discussed in th

Identification of two abundant Aerococcus urinae cell wall-anchored proteins

Aerococcus urinae is an emerging pathogen that causes urinary tract infections, bacteremia and infective endocarditis. The mechanisms through which A. urinae cause infection are largely unknown. The aims of this study were to describe the surface proteome of A. urinae and to analyse A. urinae genomes in search for genes encoding surface proteins. Two proteins, denoted Aerococcal surface protein (A

In vitro gastrointestinal digestion of mango by-product snacks : Potential absorption of polyphenols and antioxidant capacity

Mango by-products are considered cheap sources of valuable foods and nutraceutical ingredients. In this work, antioxidant capacity (AOX), and potential absorption ability (PAA) of extractable polyphenols (EP) from mango by-product snacks (MB-S) were evaluated at different stages of in vitro gastrointestinal digestion. A wheat and oat-based control snack and three MB-S formulations (F1, F2 and F3)

Integrating Ecological Indicators into Federal-State Fiscal Relations : A policy design study for Germany

Protected areas (PA) provide conservation benefits and ecosystem services that spill over the boundaries of jurisdictions to other regions. In this paper we analyse the foundations of and design options for ecological fiscal transfers (EFT) that may internalize such positive external effects. We propose a model for integrating ecological indicators into the intergovernmental fiscal transfer system

Revisiting the pharmaceuticalisation of pandemic influenza using Lukes’ framework of power

The power of social actors to drive or block pharmaceutical uptake has been a concern in sociological debates on pharmaceuticalisation, including in the case of pandemic vaccination. We build on Steven Lukes’ three-dimensional view of power to explore the 2009 H1N1 pandemic vaccination in Sweden and Denmark – two similar countries that arrived at conflicting vaccination strategies. Drawing on inte

Localization and activity of haem oxygenase and functional effects of carbon monoxide in the feline lower oesophageal sphincter

1. In the feline lower oesophageal sphincter (LOS), the distribution of the carbon monoxide (CO) producing enzymes haem oxygenase (HO)-1 and -2 was studied by immunohistochemistry and confocal microscopy, the HO activity was measured and the possible role for CO as a mediator of relaxation was investigated. 2. HO-2 immunoreactivity was abundant in nerve cell bodies of the submucosal and myenteric

Pregnancy-associated plasma protein-A2 levels are increased in early-pregnancy gestational diabetes : a novel biomarker for early risk estimation

Aim: To determine whether pregnancy-associated plasma protein-A2 levels are increased in early pregnancies complicated by gestational diabetes and whether gestation age influences levels. The possible use of pregnancy-associated plasma protein-A2 as a pre-screening biomarker to reduce the need for performing oral glucose tolerance tests in pregnant women was also investigated. Methods: Pregnant wo

Suppression of sensory C fiber-mediated contractions by neuropeptide Y Y1 receptors in the guinea pig bronchi

The aim of the study was to examine which neuropeptide Y (NPY) receptor types that are coupled to inhibition of sensory C fiber-mediated contractions of the guinea pig bronchi. NPY and PYY evoked a concentration-dependent inhibition of the electrically stimulated contractions. The Y1 receptor-selective antagonist BIBP3226 (1 microM) evoked a rightward shift of the NPY-induced response. Also the Y1

Ocular inflammation induced by electroconvulsive treatment : contribution of nitric oxide and neuropeptides mobilized from C-fibres

1. Electroconvulsive treatment (ECT) of rabbits produced ocular inflammation consisting of conjunctival hyperaemia, miosis and protein extravasation into the aqueous humour, reflected by the so-called aqueous flare response (AFR): the maximal reduction in pupil size was 3.8 +/- 0.1 mm (s.e. of mean, n = 16) while the maximal AFR was 28.1 +/- 2.8 (arbitrary units). 2. ECT also caused release of sub

Pitfalls using metalloporphyrins in carbon monoxide research

The proposal that endogenously produced carbon monoxide (CO) may act as a biological messenger has remained controversial. Carbon monoxide is generated by haem oxygenase isoenzymes in the degradation of haem-containing molecules. Certain metalloporphyrins, which are inhibitors of haem oxygenase, have been widely used as pharmacological tools in order to establish a messenger role for CO in the bra