Background: In recent years, there has been growing awareness of the distinct characteristics of adolescents and young adults (AYA) diagnosed with cancer. Soft-tissue sarcoma (STS) accounts for approximately 1% of all cancers diagnosed in adults and 8% of cancers diagnosed in AYA. To the best of our knowledge, only a few sarcoma registers include data regarding histological subtype, age at diagnos

Purpose: Epidemiologic evidence supports an association between high mammographic density and increased breast cancer risk yet etiologic mechanisms remain largely unknown. Mixed evidence exists as to whether circulating lipid levels influence mammographic density and breast cancer risk. Therefore, we examined these associations in the Nurses’ Health Study (NHS) and Nurses’ Health Study II (NHSII),

Background: Genome-wide association studies (GWAS) have identified >50 single nucleotide polymorphisms (SNP) in association with estimated glomerular filtration rate (eGFR) and chronic kidney disease (CKD) but little is known about whether the combination of these SNPs may aid in prediction of future incidence of CKD in the population. Methods: We included 2301 participants with baseline eGFR ≥60

Motivation: Comparisons of microbiome communities across populations are often based on pairwise distance measures (beta-diversity). Standard analyses (principal coordinate plots, permutation tests, kernel methods) require access to primary data if another investigator wants to add or compare independent data. We propose using standard reference measurements to simplify microbiome beta-diversity a

Background: Although free fatty acids have been positively associated with risk factors for stroke, the role of plasma free fatty acids in the development of stroke has not been elucidated in older adults. Aims: We sought to examine the association between plasma free fatty acids and incident stroke. Methods: Prospective cohort of 4369 men and women ≥65 years of age in the Cardiovascular Health St

Background: Widespread implementation of Alzheimer's disease biomarkers in routine clinical practice requires the establishment of standard operating procedures for pre-analytical handling of cerebrospinal fluid (CSF). Methods: Here, CSF collection and storage protocols were optimized for measurements of β-amyloid (Aβ). We investigated the effects of (1) storage temperature, (2) storage time, (3)

This thesis treats the intersection between two of the largest transformations we are seeing within our society today; the cloud and the Internet-of-Things (IoT). The aim of this thesis is to investigate different ways to model and control a network of cloud services so that timing-critical IoT applications can make use of them. Examples of such applications can be autonomous and mobile robots, sm

Context. Although there have been numerous studies of chemical abundances in the Galactic bulge, the central two degrees have been relatively unexplored due to the heavy and variable interstellar extinction, extreme stellar crowding, and the presence of complex foreground disk stellar populations. Aims. In this paper we discuss the metallicity distribution function, vertical and radial gradients,

Discussions and debates about traditional values of equity and inclusion have increased in recent years, and participants in these discussions include professional heritage institutions, journalists of the daily press and the public through social media. Museums, as keepers of cultural stories and heritage under their auspices, are increasingly examining their role in shaping a narrative of divers

Hållfastheten och därmed kvaliteten på planglas varierar kraftigt beroende på förekomsten sprickor i glasets yta. Sprickorna fungerar som brottanvisningar vilket medför att man måste räkna med stora säkerhetsfaktorer då glas belastas i olika byggnadskonstruktioner. Trä som konstruktionsmaterial har en liknande problematik där man utvecklat virkessortering för att kvalitetsklassning. I den här förs

In this work, we focus on the film Winter Sleep (2014) by Nuri Bilge Ceylan,whose works place special emphasis on various aspects of boredom. As one of the main figures in slow cinema, Ceylan, in this influential work of art, enable us to explore boredom through three main characters: Aydın (Haluk Bilginer), Nihal (Melisa Sözen) and Necla (Demet Akbağ). By taking a closer look at the film, we anal

In this paper, we explore how the notion of participation informs policy documents in a public library context. Today, library users to a large extent are expected to manage on their own and society calls for self-governing, active subjects who are willing to participate. To explore the notion of participation we utilize the concept of problematization and conduct a text analysis of policy documenThis article explores how the notion of participation informs policy documents in a public library context. Library users are expected to manage on their own, to a large extent, as society calls for self-governing, active subjects who are willing to participate. To explore this notion of participation, we utilize the concept of problematization and analyze policy documents regarding the public lib

BACKGROUND: There is growing evidence for a negative impact of traffic-related air pollution on risk of dementia. However, the contribution of noise exposure to this association has been rarely examined.OBJECTIVE: We aimed to investigate the individual and combined effect of noise and air pollution on risk of dementia.METHODS: Data on dementia incidence over a 15 year period was obtained from the

Nodularia spumigena is a toxic cyanobacteria that blooms in the Baltic Sea every year. In the brackish water of the Baltic Sea, its toxin, nodularin, mainly affects the biota in the surface water due to the natural buoyancy of this species. However, the fate of the toxin is unknown, once the cyanobacteria bloom enters the more saline waters of the Kattegat. In order to investigate this knowledge g

Background: A velocity offset error in phase contrast cardiovascular magnetic resonance (CMR) imaging is a known problem in clinical assessment of flow volumes in vessels around the heart. Earlier studies have shown that this offset error is clinically relevant over different systems, and cannot be removed by protocol optimization. Correction methods using phantom measurements are time consuming,