The dynamic regulation of ligand binding is considered crucial for integrin function. However, the importance of activity regulation for integrin function in vivo is largely unknown. Here, we have applied gene targeting to delete the GFFKR sequence of the lymphocyte function-associated antigen-1 (LFA-1) alpha(L) subunit cytoplasmic domain in mouse germline. Lymphocytes from Lfa-1(d/d) mutant mice

We report relativistic multiconfiguration Dirac-Hartree-Fock calculations of transitions between the hyperfine levels of 4s4f F-3(2,3) and 4s4d D-3(2) in Ga II. The capacity of two newly developed programs connected to the grasp VU package for generating synthetic spectra is explored. The obtained theoretical spectra are compared to Fourier transform spectra and good agreement is found. The import

Nonlinear harmonic generation has been described theoretically, and observed, in free-electron laser (FEL) amplifiers. The mechanism relies on the nonlinear, higher-order bunching when the fundamental reaches high intensities, and can also be expected in high-power FEL oscillators. We use the 3D polychromatic simulation code MEDUSA to study the nonlinear harmonic generation in FEL oscillators. Str

The role of weighted biharmonic Green functions in weighted Bergman spaces was first studied in the beginning of the 50's by Paul Garabedian. In 1951 he showed that they are closely related to reproducing kernel functions of weighted Bergman spaces. Half a century later, the properties of biharmonic functions turned out to be crucial to the factorization theory of Bergman spaces on the unit disk.

Dynamic models complement existing time series of observations and static critical load calculations by simulating past and future development of chemistry in forest and lake ecosystems. They are used for dynamic assessment of the acidification and to produce target load functions, that describe what combinations of nitrogen and sulfur emission reductions are needed to achieve a chemical or biolog

Abstract not available

Substantial evidence exists that reactive oxygen species participate in the pathogenesis of brain damage following both sustained and transient cerebral ischemia, adversely affecting the vascular endothelium and contributing to the formation of edema. One likely triggering event for free radical damage is delocalization of protein-bound iron. The binding capacity for some iron-binding proteins is

An affective, somatic, and memory checklist of symptoms was administered to subjects who had no personal experience or knowledge of head injury. Subjects indicated their current experiences of symptoms, then imagined having sustained a mild head injury in a motor vehicle accident, and endorsed symptoms they expected to experience six months after the injury. The checklist of symptoms was also admi

To improve cement penetration into the cancellous bone of the acetabulum in hip arthroplasty, sequential cementation of each anchoring hole may be feasible. Since this procedure creates laminations in the cement, we have determined the conditions under which such laminations affect the strength of the cement. Cement bars made at 2, 3 or 4 minutes after the start of cement mixing and with either dr

Review of Rochelle Wright, The Visible Wall. Jews and Other Ethnic Ousiders in Sweden, Acta Universitatis Upsaliensis, 1998.

The purpose of this study is to examine some factors that influence the volume of North-South trade. The study concerns the period from the early- and mid 1970s to the early 1990s. It consists of an introductory chapter and five main chapters. Chapters 2 and 3 examine trade effects of policies implemented by the North, Chapters 4 and 5 examine trade effects of policies implemented by the South, an

The aim of the study was to investigate whether the properties of a pre-sintered, hot iso-static post-compacted ( HIP) ZrO2 are adequate for use in three-five-unit fixed partial dentures (FPDs) and to evaluate the clinical results. Twenty three five-unit FPDs were fabricated for 18 patients on a total of 56 abutments. They were all made on abutments cut with a shoulder preparation and cemented wit

Capsule Nest survival rates could not be explained by distance to habitat edges or other features used by predators. Aims To investigate if predation on Redshank nests was affected by habitat characteristics at a local scale. Methods We examined survival rates of Redshank nests on coastal meadows on the Baltic island of Gotland, Sweden, over two breeding seasons. We analysed nest survival rates

Popular Abstract in Swedish Svenska myndigheter behöver ibland samarbeta med utländska myndigheter, till exempel i ärenden som rör personer, föremål eller information som finns utomlands. Detta kan leda till komplexa juridiska problem som kräver pragmatiska lösningar. I avhandlingen undersöks rättsliga ramar för sådana lösningar. Undersökningen är särskilt inriktad på rättsligt bindande avtal som When Swedish administrative authorities co-operate with foreign administrative authorities, this may give rise to legally complex situations. This thesis investigates legal frameworks to solve the ensuing problems. The investigation in particular deals with binding agreements concluded by Swedish state authorities and municipalities with corresponding types of foreign public bodies. By the conclus