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Intergenerational Transmission of Human Capital : Is it a One-Way Street?

Studies on the intergenerational transmission of human capital usually assume a one-way spillover from parents to children. However, children may also affect their parents’ human capital. Using exogenous variation in education, arising from a Swedish compulsory schooling reform in the 1950s and 1960s, we address this question by studying the causal effect of children's schooling on their parents’

Hybrid control of a manufacturing transport system

This paper describes the design of a least restrictive, safe hybrid control scheme for a manufacturing transport system transporting fragile objects from a production unit to a stamping/packaging station. The control scheme consists of several control modes. One control mode handles trajectory following using time-optimal control, the other control modes are safety related and are engaged in a lea

Histone profiling reveals the H1.3 histone variant as a prognostic biomarker for pancreatic ductal adenocarcinoma

Background: Epigenetic alterations have been recognized as important contributors to the pathogenesis of PDAC. However, the role of histone variants in pancreatic tumor progression is still not completely understood. The aim of this study was to explore the expression and prognostic significance of histone protein variants in PDAC patients. Methods: Liquid chromatography-tandem mass spectrometry (

Timing of oral anticoagulant therapy in acute ischemic stroke with atrial fibrillation : Study protocol for a registry-based randomised controlled trial

Background: Oral anticoagulation therapy is recommended for the prevention of recurrent ischemic stroke in patients with atrial fibrillation (AF). Current guidelines do not provide evidence-based recommendations on optimal time-point to start anticoagulation therapy after an acute ischemic stroke. Non-vitamin K antagonist oral anticoagulants (NOACs) may offer advantages compared to warfarin becaus

Arterial stiffness and incidence of diabetes : A population-based cohort study

Objective: Diabetes is known to be associated with increased arterial stiffness. However, the temporal association between increased carotid-femoral pulse wave velocity (c-f PWV) and diabetes is unclear. The aim of this study is to explore the relationship between arterial stiffness, as determined by c-f PWV, and incidence of diabetes. Research Design and Methods: The study population included par

Dimethylguanidino valeric acid is a marker of liver fat and predicts diabetes

Unbiased, “nontargeted” metabolite profiling techniques hold considerable promise for biomarker and pathway discovery, in spite of the lack of successful applications to human disease. By integrating nontargeted metabolomics, genetics, and detailed human phenotyping, we identified dimethylguanidino valeric acid (DMGV) as an independent biomarker of CT-defined nonalcoholic fatty liver disease (NAFL

Exosomes and microvesicles in normal physiology, pathophysiology, and renal diseases

Extracellular vesicles are cell-derived membrane particles ranging from 30 to 5,000 nm in size, including exosomes, microvesicles, and apoptotic bodies. They are released under physiological conditions, but also upon cellular activation, senescence, and apoptosis. They play an important role in intercellular communication. Their release may also maintain cellular integrity by ridding the cell of d

Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer

Most common breast cancer susceptibility variants have been identified through genome-wide association studies (GWAS) of predominantly estrogen receptor (ER)-positive disease1. We conducted a GWAS using 21,468 ER-negative cases and 100,594 controls combined with 18,908 BRCA1 mutation carriers (9,414 with breast cancer), all of European origin. We identified independent associations at P < 5 × 10-8

Control of a turbo charged NVO HCCI engine using a model based approach

By using a turbo the operating range of the HCCI engine can be increased, but at the expense of increased controller complexity. The dynamics the turbo introduces in the intake and the exhaust manifolds, have a large impact on the in-cylinder mixture temperature, pressure and finally the combustion phasing. To compensate for this and to maintain desired combustion phasing, precise control of the n

Modeling the intake CO2-level during Load Transients on a 1-cylinder heavy duty di diesel engine

For diesel engines the major exhaust problem is particulate matter and NOx emissions. To reduce NOx, exhaust gas recirculation (EGR) is often used. The behavior of the EGR-level will therefore influence the emissions and it is therefore valuable to keep track of the EGR-level. Especially during transients it is difficult to predict how the EGR-level varies. In this paper the CO2-level in the intak

Observed Learning Outcomes of Integrated Communication Training in Science Education: Skills and Subject Matter Understanding

In this paper we explore how different ways of training communication skills can be successfully implemented in higher education, and which effects these activities may have on science students’ learning. Using content analysis, we studied a material consisting of 34 reports, written by 70 academic science teachers, as part of a teacher-training course on communication in science higher education.

Low power piezoelectric micro mass flow controller for liquid fuel injection

Utilization of an ethanol driven, combustion-based power generator promises high-efficiency combustion in diesel-like engines and avoids problems connected to shrinking supplies of fossil fuels since fuels like ethanol or dimethyl ether can be produced from renewable resources. Fuel injection into such generator through a piezoelectric micro mass flow controller (MMFC) features low power consumpti

Multi-Output Control of a Heavy Duty HCCI Engine Using Variable Valve Actuation and Model Predictive Control

Autoignition of a homogeneous mixture is very sensitive to operating conditions, therefore fast control is necessary for reliable operation. There exists several means to control the combustion phasing of an Homogeneous Charge Compression Ignition (HCCI) engine, but most of the presented controlled HCCI result has been performed with single-input single-output controllers. In order to fully operat

Fem år av tillgänglighet, närhet och synlighet : LUB:s forskarstöd 2012-2017

För fem år sedan publicerades ”Tillgänglighet, närhet och synlighet”, en slutrapport för ett projekt som syftade till att inventera forskares behov av forskarstöd vid LU. I år, 2017, valde arbetsgruppen för Forskning och Forskningsprocesser inom LUB, att göra om en av delarna i projektet nämligen den enkätundersökningen som gick ut till de olika delarna av biblioteksorganisationen och som låg till