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Assessing the Inventiveness of Bio-Pharmaceuticals under European and US Patent Law - A comparative study with special emphasis on DNA- and protein-related inventions

“The implications and applications of biotechnology continue to be at the centre of public debate. In the light of rapid scientific advances and novel insights, the multi-faceted discussions are particularly fierce with regard to patents on DNA–related technology. In the often very emotionally-led debate basically two directly conflicting schools of thoughts can be identified. Some people believe

Low complexity channel estimation for low-mobility LTE using 4×4 MIMO

Multiple-input multiple-output (MIMO) is a mandatory feature of the Third Generation Partnership Project (3GPP) Long Term Evolution. This work investigates the performance of a low complexity channel estimator for LTE terminals with an emphasis on the 4 × 4 multiple antenna scheme. The presented work extends a promising low-complexity 2 × 2 MIMO channel estimator to the 4 × 4 MIMO case and evaluat

Autofluorescence of pigmented skin lesions using a pulsed UV laser

We report preliminary clinical results of autofluorescence imaging of malignant and benign skin lesions, using pulsed 355 nm laser excitation with synchronized detection. The novel synchronized detection system allows high signal-tonoise ratio to be achieved in the resulting autofluorescence signal, which may in turn produce high contrast images that improve diagnosis, even in the presence of ambi

Mot koldioxidsnåla godstransporter-tillväxtdynamiskt perspektiv på logistik och godstransporter fram till 2050 : Tillväxtdynamiskt perspektiv på logistik och godstransporter fram till 2050

Det är både tekniskt möjligt och ekonomiskt genomförbart att ställa om till ett CO 2-snålt samhälle2050. Men för att nå en sådan målsättning måste ett antal utmaningar och hinder övervinnas, vilketkan kräva både politisk styrning och institutionell förändring.Denna rapport fokuserar specifikt på samspelet mellan utvecklingen av godstransporter, logistik ochCO 2-utsläpp. Godstransporterna, som styr

Role of Endogenous BDNF and NT3 for Synaptic Transmission and Plasticity in the Dentate gyrus

Popular Abstract in Swedish Tillväxtfaktorer påverkar signaler mellan celler i hjärnan Människors hjärnor innehåller flera miljarder hjärnceller, vilka är förutsättningen för vårt beteende, våra känslor och våra tankar. Hjärncellerna bildar kontakter, synapser, med varandra. Genom dessa överförs signaler från en cell till en annan. Varje cell kontaktar en mängd andra celler, både sådana med liknanThe neurotrophins, notably brain-derived neurotrophic factor (BDNF) and neurotrophin 3 (NT3), modulate synaptic transmission and synaptic plasticity in the adult mammalian brain. Recent data suggest that neurotrophins might be mediators of activity-dependent synaptic plasticity. Such plasticity is believed to be a cellular correlate for important processes like learning, but also for diseases, for

Pollen Luftföroreningar Allergi

Abstract in Undetermined Detta häfte informerar om pollen och pollenallergi samt de viktigaste resultaten från ett utvecklingsprojekt som genomförts av Göteborgs universitet, Institutionen för biologi och miljövetenskap. Länsstyrelsen i Västra Götalands län har varit samordnare för projektet. Länsstyrelsen i Skåne, Region Skåne, VTI samt Arbets- och miljömedicin, Göteborgs universitet har deltagit

Inequality and the working class in Scandinavia 1800 to 1910. Workers’ share of growing income

One of the major ways in which economic inequality can increase is when the development of wages of ordinary workers trail productivity and GDP growth, meaning that the increasing riches fall in the hand of other social groups (top employees, owners of land and capital). This paper investigates the relationship between wages and GDP in Denmark, Norway and Sweden from 1800 to 1910, using wage serie

Cliticisation in the acquisition of French as L1 and L2

The intense debate on continuity in child grammars has largely focused on the existence of Functional Categories (FCs) in early grammars despite differences in language use with adults (e.g., omissions, word order errors, lack of case marking). Simplified, the major theoretical explanations for these properties range from Maturational accounts (Radford 1990 and later) claiming an initial absence o

Adaptive Detection of a Partly Known Signal Corrupted by Strong Interference

In this letter, we consider adaptive detection of a partly known signal corrupted by additive noise and strong interference with support that is only partly known. Assuming a homogeneous environment where the covariance matrix of the additive noise is the same for the primary and secondary data sets, although with the secondary data set also being affected by the interference, we allow for conic u

Singular Inverse Wishart Distribution with Application to Portfolio Theory

The inverse of the standard estimate of covariance matrix is frequently used in the portfolio theory to estimate the optimal portfolio weights. For this problem, the distribution of the linear transformation of the inverse is needed. We obtain this distribution in the case when the sample size is smaller than the dimension, the underlying covariance matrix is singular, and the vectors of returns a