Search results

Filter

Filetype

Your search for "*" yielded 528613 hits

Self-triggered controllers, resource sharing, and hard guarantees

Today, many control applications in embedded and cyber-physical systems are implemented on shared platforms, alongside other hard real-time or safety-critical applications. Having the resource shared among several applications, to provide hard guarantees, it is required to identify the amount of resource needed for each application. This is rather straightforward when the platform is shared among

Postoperative pain treatment after lumbar discectomy. A protocol for a systematic review with meta-analysis and trial sequential analysis

Background: Patients undergoing lumbar discectomy usually suffer from moderate to severe pain during the postoperative period. Multimodal, or balanced analgesia, is the leading treatment principle for managing postoperative pain. The rationale is to achieve optimal pain treatment through additive or synergistic effects of several non-opioid analgesics, and thereby, reducing the need for postoperat

Characteristics of Patients in Treatment for Alcohol and Drug Addiction Who Succeed in Changing Smoking, Weight, and Physical Activity : A Secondary Analysis of an RCT on Combined Lifestyle Interventions

Introduction: Patients addicted to alcohol or drug often have additional unhealthy lifestyles, adding to the high mortality and morbidity in this patient group. Therefore, it is important to consider lifestyle interventions as part of the usual addiction treatment. Objective: The aim was to identify predictors of successful changes in lifestyle risk factors among patients in treatment for alcohol

Key components of successful transition for adolescents born with anorectal malformations-a Nordic focus group study

Transitional care for adolescents with congenital malformations, such as anorectal malformations (ARM), is described sparsely in the literature and referred to as being inadequate. In order to organize future successful healthcare structures, knowledge of patient-reported important aspects of transition is required. The aim of the study was therefore to explore the needs and expectations of transi

Pursuing behavioral realism in Virtual Reality for fire evacuation research

The use of virtual reality in human behavior in fire research has the advantage of being able to produce results comparable to more traditional laboratory or field experiments. This method relies not only on the technology employed but also on the participants' perception of realism when exposed to a virtual emergency scenario. A virtual scenario can be perceived as realistic based on the way it l

Characteristic modes extraction of dielectric bodies using pulse functions

This paper focuses on the use of pulse functions and point matching method to construct the impedance matrix needed for the characteristic mode analysis of dielectric bodies. Taking the results given by a commercial Method of Moments (MoM) solver as a benchmark, the proposed method is shown to facilitate accurate characteristic eigenvectors and eigenvalues on these structures using low order basis

An "export-only" exception to pharmaceutical patents in Europe: Should the U.S. follow suit?

A new European Union policy could increase the supply of legitimate pharmaceuticals in developing countries and thereby minimize the problem of counterfeit medicines, but many challenges remain. This paper describes the proposed European legislation and discusses its' potential strengths, weaknesses, opportunities and threats. Ultimately, we consider if the United States should consider similar po

Modelling the impacts of climate change on soybeans water use and yields in Ogun-Ona river basin, Nigeria

African countries such as Nigeria are anticipated to be more susceptible to the impacts of climate change due to reliance on rainfed agriculture. In this regard, the impacts of climate change on crop water requirements (CWR), yields and crop water productivity (CWP) of soybean in the Ogun-Ona River Basin, Nigeria, were evaluated for the baseline period (1986–2015) and future period (2021–2099) und

Comprehensive lipidomics in apoM−/− mice reveals an overall state of metabolic distress and attenuated hepatic lipid secretion into the circulation

Apolipoprotein M (apoM) participates in both high-density lipoprotein and cholesterol metabolism. Little is known about how apoM affects lipid composition of the liver and serum. In this study, we systemically investigated the effects of apoM on liver and plasma lipidomes and how apoM participates in lipid cycling, via apoM knockout in mice and the human SMMC-7721 cell line. We used integrated mas

Brevican and Neurocan Peptides as Potential Cerebrospinal Fluid Biomarkers for Differentiation Between Vascular Dementia and Alzheimer's Disease

BACKGROUND: Brevican and neurocan are central nervous system-specific extracellular matrix proteoglycans. They are degraded by extracellular enzymes, such as metalloproteinases. However, their degradation profile is largely unexplored in cerebrospinal fluid (CSF).OBJECTIVE: The study aim was to quantify proteolytic peptides derived from brevican and neurocan in human CSF of patients with Alzheimer

High platelet count is associated with low bone mineral density : The MrOS Sweden cohort

Summary: In elderly ambulatory men, high platelet and high neutrophil counts are related to low bone mineral density (BMD), after adjustment for relevant covariates. Low hemoglobin (hgb) is even associated with low BMD, but this relationship seems to be dependent on estradiol and osteocalcin. Purpose: Blood and bone cells exist in close proximity to each other in the bone marrow. Accumulating evid

The RIFM approach to evaluating Natural Complex Substances (NCS)

The Research Institute for Fragrance Materials, Inc. (RIFM) has evaluated safety data for fragrance materials for 55 years. The safety assessment of Natural Complex Substances (NCS) is similar to that of discrete fragrance materials; all of the same endpoints are evaluated. A series of decision trees, reflecting advances in risk assessment approaches of mixtures and toxicological methodologies, fo

Three-dimensional mapping of neurofibrillary tangle burden in the human medial temporal lobe

Tau protein neurofibrillary tangles are closely linked to neuronal/synaptic loss and cognitive decline in Alzheimer's disease and related dementias. Our knowledge of the pattern of neurofibrillary tangle progression in the human brain, critical to the development of imaging biomarkers and interpretation of in vivo imaging studies in Alzheimer's disease, is based on conventional two-dimensional his

The external effects of offshoring on job security in SMEs

We investigate the effects of offshoring on job security using matched employer-employee data from Sweden. Between 1997 and 2011, the share of offshoring firms fell from around 25 to 22% while offshoring per worker within offshoring firms almost doubled. We use this variation to contribute to the literature by examining the effects of the neighboring firms’ offshoring (external offshoring) on job

Long-Term Risk of Hip Complications After Radiation Therapy for Prostate Cancer : A Dose-Response Study

Purpose: The aim of the present study was to analyze the long-term incidence of hip complications after external beam radiation therapy compared with age-matched controls from the general population. We also investigated whether there were any dose−response associations. Methods and materials: A total of 349 patients with prostate cancer treated to curative dose with external beam radiation therap

Risk factors for hospital readmission in older adults within 30 days of discharge - a comparative retrospective study

BACKGROUND: The area of hospital readmission in older adults within 30 days of discharge is extensively researched but few studies look at the whole process. In this study we investigated risk factors related, not only to patient characteristics prior to and events during initial hospitalisation, but also to the processes of discharge, transition of care and follow-up. We aimed to identify patient