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An electrochromatography chip with integrated waveguides for UV absorbance detection

A silicon-based microchip for electrochromatographic separations is presented. Apart from a microfluidic network, the microchip has integrated UV-transparent waveguides for detection and integrated couplers for optical fibers on the chip, yielding the most complete chromatography microchip to date in terms of the integration of optical components. The microfluidic network and the optical component

Simultaneous native UV fluorescence and absorbance detection for microchip electrophoresis using integrated waveguides

This paper reports simultaneous detection of ultra violet (UV) absorbance and native UV-excited fluorescence in an electrophoresis microchip using UV transparent integrated waveguides. Absorbance detection enables detection of a wide range of analytes. When exposed to UV light, some compounds also exhibit native fluorescence, which is here detected simultaneously. Calibration curves were measured

Cyclic olefin polymers : Emerging materials for lab-on-a-chip applications

Cyclic olefin polymers (COPs) are increasingly popular as substrate material for microfluidics. This is due to their promising properties, such as high chemical resistance, low water absorption, good optical transparency in the near UV range and ease of fabrication. COPs are commercially available from a range of manufacturers under various brand names (Apel, Arton, Topas, Zeonex and Zeonor). Some

Continuous acoustic sorting of E. Coli and G. Lamblia in drinking water

This paper presents an acoustofluidic chip for the sorting of bacteria from protozoa in water using standing acoustic waves. The size-based acoustophoretic sorting method provides a means for sample pre-concentration, which is vital for real-time, on-site monitoring of drinking water quality and preventing outbreak of waterborne diseases. In practice, high throughput and high recovery pre-concentr

Build your own soil : exploring microfluidics to create microbial habitat structures

Soil is likely the most complex ecosystem on earth. Despite the global importance and extraordinary diversity of soils, they have been notoriously challenging to study. We show how pioneering microfluidic techniques provide new ways of studying soil microbial ecology by allowing simulation and manipulation of chemical conditions and physical structures at the microscale in soil model habitats.The

O/W emulsions stabilized by OSA-modified starch granules versus non-ionic surfactant : Stability, rheological behaviour and resveratrol encapsulation

Resveratrol is a natural phenol with many positive effects for human health. However it is a photosensitive molecule with geometric isomerism, easily oxidised with short biological half-life and rapid metabolism and elimination. Thus, encapsulation of resveratrol is necessary. It has low solubility in water and in most of common oils. The goal of this work was to prepare oil-in-water emulsion stab

Experimental and modeling studies of a biofuel surrogate compound : laminar burning velocities and jet-stirred reactor measurements of anisole

Lignocellulosic biomass is a promising alternative fuel source which can promote energy security, reduce greenhouse gas emissions, and minimize fuel consumption when paired with advanced combustion strategies. Pyrolysis is used to convert lignocellulosic biomass into a complex mixture of phenolic-rich species that can be used in a transportation fuel. Anisole (or methoxybenzene) can be used as a s

Industrialized Building Companies' Business Models : Multiple Case Study of Swedish and North American Companies

Industrialized building companies apply various product predefinition strategies, derived from market- or resource-based strategic perspectives. This strongly affects the buildup of such companies' business models and their operational structure. Ten companies were included in a case study, presenting strategic orientations and business models. The aim of this study was to analyze the primary char

Lay theories in comparative research

The paper addresses the theoretical concept and methodological usefulness of 'lay theories' for conducting comparative research. 'Lay knowledge' is a well-researched concept particularly in medicine and health (e.g. Williams & Popay 2006), even if often regarded as an 'obstacle' that needs to be overcome in order to spread 'proper' scientific, medical knowledge. Critical studies within medicin

Molecular, micro- and ultrastructural investigations of labile tissues in deep time

Denna avhandling behandlar en mängd mikrostrukturella och molekylära lämningar som påträffats i ett antal fossil. Resultaten presenteras i sex vetenskapliga artiklar med det gemensamma syftet att grundligt studera dessa lämningar med hjälp av såväl nya som vedertagna analysmetoder. Avhandlingens huvudsakliga frågeställningar är dels vad denna typ av fossila spår kan säga om de studerade djurens biThis thesis comprises investigations of microstructures and molecular remains, preserved in a variety of fossil specimens. The results are presented in six papers, collectively aiming to thoroughly examine fossil traces of such remains by employing a combination of both established and relatively new analytical methods. The main questions asked are: What can we learn about the biology, ecology and

Factor H–IgG chimeric proteins as a therapeutic approach against the gram-positive bacterial pathogen Streptococcus pyogenes

Bacteria can cause life-threatening infections, such as pneumonia, meningitis, or sepsis. Antibiotic therapy is a mainstay of treatment, although antimicrobial resistance has drastically increased over the years. Unfortunately, safe and effective vaccines against most pathogens have not yet been approved, and thus developing alternative treatments is important. We analyzed the efficiency of factor

Skin hydration : Interplay between molecular dynamics, structure and water uptake in the stratum corneum

Hydration is a key aspect of the skin that influences its physical and mechanical properties. Here, we investigate the interplay between molecular and macroscopic properties of the outer skin layer - the stratum corneum (SC) and how this varies with hydration. It is shown that hydration leads to changes in the molecular arrangement of the peptides in the keratin filaments as well as dynamics of C-

Cystatin B, cathepsin L and D related to surrogate markers for cardiovascular disease in children

Objective: This study investigated potential associations between novel biomarkers for cardiovascular disease and other surrogate markers for health. Methods: Community sample of 170 (92 boys and 78 girls) children aged 8–11 years. Total fat mass (TBF) and abdominal fat (AFM) were measured by Dual-energy x-ray absorptiometry (DXA). Total body fat was also expressed as percentage of total body mass

Från kraftprov till systembejakande talmagi : Jubileer i antiken

This paper highlights and discusses the concept of the jubilee in Antiquity through a series of case studies. The ancient jubilee is defined as a temporally based, and often recurring, communal celebration, which encompasses longer time spans, from ten to a thousand years. The examples elaborated on by the present authors are: the Jewish Yovel, the Egyptian Heb-Sed and the Roman decennalia (Leande

Search for new high-mass phenomena in the dilepton final state using 36 fb−1 of proton-proton collision data at √s=13 TeV with the ATLAS detector

A search is conducted for new resonant and non-resonant high-mass phenomena in dielectron and dimuon final states. The search uses 36.1 fb−1 of proton-proton collision data, collected at s=13 TeV by the ATLAS experiment at the LHC in 2015 and 2016. No significant deviation from the Standard Model prediction is observed. Upper limits at 95% credibility level are set on the cross-section times branc

Combining modern plant breeding and enzyme technology to obtain highly enriched erucic acid from Crambe oil

BackgroundFatty acids from vegetable oils are useful building blocks for industrial materials. The purpose of this work was to prepare erucic acid with high purity from a vegetable oil. High purity erucic acid is used for the production of erucamide with applications in plastics manufacturing. A newly developed transgenic Crambe line produces seed oil with 68 % erucic acid compared to 53 % in the

Status determination of a historical building including measures for three different scenarios

Today there is a need for energy-efficiency measures in historic buildings. Clarifying both opportunities and risks for energy-efficiency measures in historic buildings is a challenging task. To ensure that such measures will provide the planned result without damage to the building or poor indoor climate, a skilled holistic approach is required. To be able to propose accurate measures requires a