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Techno-economic and life-cycle analyses of dark fermentative hydrogen production integrated with anaerobic digestion from coffee-manufacturing wastewater under thermophilic and mesophilic conditions

Techno-economic analysis and life cycle assessment of thermophilic dark fermentation (TDF) and mesophilic dark fermentation (MDF) integrated with anaerobic digestion (AD) from coffee-manufacturing wastewater (CW) as feedstock were studied. The pilot plants were based in Iran and designed to convert 800 m3/day of CW into hydrogen. The hydrogen volume flow rate (m3/h) under thermophilic conditions w

The use, energy use and renovation of Swedish second homes in winter sport areas

The growing utilization of second homes has led to extended heating periods and, to some extent, renovations to enhance their standards, resulting in increased energy and resource consumption. This study, conducted in Sweden, investigates user patterns across various seasons, heating systems, and implemented energy renovation measures. Findings reveal that 40% of second homes in winter sport areas

Assessing housing accessibility issues for older adults in Japan : an expert panel approach to cross-cultural adaptation and content validity of the Japanese housing enabler

Accessible housing plays a crucial role in supporting aging in place, yet Japan lacks adequate tools for assessing housing accessibility among older adults. This study describes the process of translating and adapting the environmental component checklist of the Swedish Housing Enabler instrument for valid use in Japan. During translation to the Japanese language, technical terms and specification

4MOST : the 4-metre multi-object spectroscopic telescope project in the assembly, integration and test phase

4MOST is a new high-multiplex, wide-field spectroscopic survey facility under construction for ESO's 4m-VISTA telescope at Paranal, Chile. Its key specifications are: a large field of view of 4.4 square degrees, a high multiplex fibre positioner based on the tilting spine principle that positions 2436 science fibres in the focal surface of which 1624 fibres go to two low-resolution optical spectro

4MOST - 4-metre multi-object spectroscopic telescope

The 4MOST consortium is currently halfway through a Conceptual Design study for ESO with the aim to develop a wide-field (>3 square degree, goal >5 square degree), high-multiplex (>1500 fibres, goal 3000 fibres) spectroscopic survey facility for an ESO 4m-class telescope (VISTA). 4MOST will run permanently on the telescope to perform a 5 year public survey yielding more than 20 million spectra at

Adsorption of bile salts onto crystalline ritonavir particles under simulated gastrointestinal conditions

The formation of a biomolecular corona on nanoparticles in blood is a well-known phenomenon influencing in vivo performance. Analogous phenomena in other biological fluids, such as the formation of a gastrointestinal (GI) corona, remain under-investigated. The ingestion of medicines leads to the generation of drug particles in the GI fluids. Consequently, an understanding of the behavior of drug p

Limitations and rotation of the two-armed phase spiral in the Milky Way stellar disc

Context. The Milky Way’s history of recent disturbances is vividly demonstrated by a structure in the vertical phase-space distribution known as the Gaia phase spiral. A one-armed phase spiral has been seen widely across the Milky Way disc, while a two-armed one has only been observed in the solar neighbourhood.Aims. This study aims to determine the properties of the two-armed phase spiral and to

Boussinesq's equation for water waves : Asymptotics in Sector i

In a recent study, we showed that the large (x, t) behavior of a class of physically relevant solutions of Boussinesq's equation for water waves is described by ten main asymptotic sectors. In the sector adjacent to the positive x x -axis, referred to as Sector I, we stated without proof an exact expression for the leading asymptotic term together with an error estimate. Here, we provide a proof o

On ultrafast x-ray scattering methods for magnetism

With the introduction of x-ray free electron laser sources around the world, new scientific approaches for visualizing matter at fundamental length and time-scales have become possible. As it relates to magnetism and ‘magnetic-type’ systems, advanced scattering methods are being developed for studying ultrafast magnetic responses on the time-scales at which they occur. We describe three capabiliti

Comparing phase sensitive detection and Fourier analysis of modulation excitation spectroscopy data exemplified by Ambient Pressure X-ray Photoelectron Spectroscopy

Dynamic processes in catalysis are gaining increased attention and could very well be one of the next frontiers in surface science. One way to study such processes is to induce chemical changes on the surface for example by periodically adjusting the (electro)chemical potential in situ and identify the resulting spectral changes. Often this is referred to as Modulation Excitation Spectroscopy (MES

Impact of site-specific conjugation strategies on the pharmacokinetics of antibody conjugated radiotherapeutics

Antibody radionuclide conjugates are an emerging modality for targeted imaging and potent therapy of disseminated disease. Coupling of radionuclides to monoclonal antibodies (mAbs) is typically achieved by applying non-site-specific labelling techniques. With the ambition of reducing variability, increasing labelling efficacy and stability, several site-specific conjugation strategies have been de

Mammographic features differ with body composition in women with breast cancer

Objectives: There are several breast cancer (BC) risk factors—many related to body composition, hormonal status, and fertility patterns. However, it is not known if risk factors in healthy women are associated with specific mammographic features at the time of BC diagnosis. Our aim was to assess the potential association between pre-diagnostic body composition and mammographic features in the diag

Impacts of microplastic ingestion on fish communities in Haizhou Bay, China

Microplastics are pervasive throughout aquatic ecological communities. While their negative impacts on the life history traits of aquatic species are well studied, the effects on community dynamics remain elusive. Consequently, community-level assessments of microplastic effects on marine food webs are largely lacking, creating significant knowledge gaps regarding marine ecosystem structure and dy

Biological mechanisms of resilience to tau pathology in Alzheimer’s disease

Background: In Alzheimer’s disease (AD), the associations between tau pathology and brain atrophy and cognitive decline are well established, but imperfect. We investigate whether cerebrospinal fluid (CSF) biomarkers of biological processes (vascular, synaptic, and axonal integrity, neuroinflammation, neurotrophic factors) explain the disconnection between tau pathology and brain atrophy (brain re

Organizing employee-driven innovation (EDI) through game-based formats : Understanding participation

The awareness of employee-driven innovation (EDI) and its strategic relevance to corporate development has recently increased. The implications of EDI are vigorously discussed in terms of inclusive approaches; particularly focussing on how managerial structures can enable employee participation. This paper focusses on game-based formats to enhance such participation and explores what participation

New connections of medication use and polypharmacy with the gut microbiota composition and functional potential in a large population

Medication can affect the gut microbiota composition and function. The aim of this study was to investigate connections between use of common non-antibiotic medicines and the gut microbiota composition and function in a large Swedish cohort (N = 2223). Use of 67 medications and polypharmacy (≥ 5 medications), based on self-reported and prescription registry data, were associated with the relative

Decreasing incidence of celiac disease in Southern Sweden

Background: The incidence of celiac disease (CD) has increased rapidly in the late 20th and early 21st centuries, but there are recent reports of rates levelling off in countries with a high prevalence. The aim of this study was to investigate current trends in CD in southern Sweden. Patients and methods: Children and adults diagnosed with CD by biopsy or serology in the region of Skåne, southern