The ability of new neurons to promote repair of brain circuitry depends on their capacity to re-establish afferent and efferent connections with the host. In this review article, we give an overview of past and current efforts to restore damaged connectivity in the adult mammalian brain using implants of fetal neuroblasts or stem cell-derived neuronal precursors, with a focus on strategies aimed t

Introducing the concept of semantic representation in the brain as well as highlighting their relevance for day-to-day human functioning. Presenting a brief overview of different theoretical viewpoints on semantic representation in the brain along with empirical evidence implicating brain areas designated for semantic processing. Illustrating how statistical semantics and semantic spaces have been

Stem cell transplantation can improve behavioral recovery after stroke in animal models but whether stem cell-derived neurons become functionally integrated into stroke-injured brain circuitry is poorly understood. Here we show that intracortically grafted human induced pluripotent stem (iPS) cell-derived cortical neurons send widespread axonal projections to both hemispheres of rats with ischemic

Semantic analyses are potentially important, but underutilized, tools to study social psychology. This chapter focuses on how semantic analysis, using personal pronouns, can be used to study important phenomena in social psychology. Personal pronouns can be used as proxies for social categories, and the semantic contexts associated to these pronouns can be used to study stereotypes and how groups

The aims of this chapter include describing: how the semantic representations may be used to measure the semantic similarity between words. the validity of semantic similarity as measured by cosine. how semantic similarity scales can be used in research. how to apply t-test to compare two sets of texts using semantic similarity (i.e. “semantic” t-test). how to visualize the word responses by plott

This chapter focuses on using the semantic representations, consisting of a number of semantic dimensions, in multiple linear regressions to predict a numerical outcome variable. We examine whether there is a statistically significant relationship between texts and numerical values. Hence, we ask the question to what extent it is possible to predict numerical (or categorical) data from text data?.

Human beings create meaning from the fact that concepts tend to occur together in a predictable way. When we see a dog, we also see a tail, paws, eyes, legs, fur, and etcetera. In this context, we would see an owner who goes for a walk in the park with the dog that is attached to a leach, and the dog might bark. Thus, the concept of a dog is connected with these other concepts, and when these conc

BACKGROUND: Universal access to safe drinking water and sanitation facilities is an essential human right, recognised in the Sustainable Development Goals as crucial for preventing disease and improving human wellbeing. Comprehensive, high-resolution estimates are important to inform progress towards achieving this goal. We aimed to produce high-resolution geospatial estimates of access to drinkin

Certain mental processes are suggested to exist beyond conscious awareness and control. These processes have often been categorized as implicit, in contrast to explicit, processes, which are readily available to conscious report. Researchers have attempted to measure and assess these implicit processes in a different number of ways. Projective measures, for instance, present ambiguous or unstructu

To ameliorate the thermal management of a regenerative cooling system in an advanced engine, the turbulence characteristics and entropy generation in a buoyancy-driven supercritical hydrocarbon fuel flow are numerically explored in detail. Several common buoyancy criteria (Gr/Re2, Gr/Re2.7 and Grq/Grth) are established and a three-dimensional numerical model is solved with an advanced LES model. T

Natural radioactivity in the environment is a field gaining more attention in last decades. This work is focused on the study of natural radioactivity complemented with elementary characterization at former non-uraniferous mining areas in Sweden. This aim is addressed through the study of mining lakes, called pit lakes, which are water bodies generated after opencast mining. Environmental matrices

Coxsackievirus A24 variant (CVA24v) is a major causative agent of acute hemorrhagic conjunctivitis outbreaks worldwide, yet the evolutionary and transmission dynamics of the virus remain unclear. To address this, we analyzed and compared the 3C and partial VP1 gene regions of CVA24v isolates obtained from five outbreaks in Cuba between 1986 and 2009 and strains isolated worldwide. Here we show tha

Cerebrospinal fluid (CSF) neurofilament light (NfL) concentration has reproducibly been shown to reflect neurodegeneration in brain disorders, including Alzheimer's disease (AD). NfL concentration in blood correlates with the corresponding CSF levels, but few studies have directly compared the reliability of these 2 markers in sporadic AD. Herein, we measured plasma and CSF concentrations of NfL i

(“Dissolved organic carbon leaching flux in a mixed agriculture and forest watershed in Rwanda” [1]). This article presents data of leached dissolved organic carbon (LDOC), stream water dissolved organic carbon), rainfall amount (Ra), rainfall intensity (Ri), rainfall soil storage (S), runoff (Q), and soil properties such as total organic carbon (TOC), total nitrogen (TN), cation exchange capacity

A growing body of consumer culture theory (CCT) research has pointed to the way that places are increasingly conceptualised and commodified as brands and consumption objects (Lichrou et al., 2008; Giovanardi et al., 2018). Research has explored consumers’ experiences with different kinds of spaces and places, including retail settings (e.g. Penaloza, 1998; Kozinets et al., 2004; Maclaran & Bro

OBJECTIVE: To compare the pain course between methotrexate (MTX)-refractory early rheumatoid arthritis (RA) patients randomised to infliximab (IFX) versus sulfasalazine+hydroxychloroquine (SSZ+HCQ).METHODS: The randomised, controlled, open-label SWEFOT (SWedish FarmacOTherapy) trial enrolled new-onset RA patients Oct 2002-Dec 2005. After 3 months on MTX, patients not reaching low disease activity

Introduction: Intracerebral hemorrhage (ICH) is the most serious adverse effect of oral anticoagulant (OAC) treatment. The effect of OAC reversal therapy on outcome is uncertain. We compared 90-day survival and functional outcome in patients with OAC-ICH who received OAC reversal therapy with those who did not. Methods: Data from The Swedish Stroke Register (Riksstroke) for all registered cases of