This update of the Landsteiner-Wiener (LW) blood group system (Grandstaff Moulds MK. The LW blood group system: a review. Immunohematology 2011;27:136-42. Storry JR. Review: the LW blood group system. Immunohematology 1992;8:87-93) reports new information on the distribution of genetic variants in ICAM4 and reviews the complex serologic identification of the high-prevalence LWEM antigen. The role

This chapter explores moral and ethical discussions that emerged in Sweden when the number of artificial grass pitches rose substantially. Based on research in the Swedish top-tier football league, named Allsvenskan, I shall present conflicting discourses that appear whenever grass is considered. The grass discussions often take a wider, political turn and reflect attitudes towards developments in

Purpose: A new biodegradable liquid fiducial marker was devised to allow for easy insertion in lung tumors using thin needles. The purpose of this study was to evaluate the visibility of the liquid fiducial markers for image-guided radiation therapy and compare to existing solid fiducial markers and to one existing liquid fiducial marker currently commercially available. Methods: Fiducial marker v

Proton therapy has the potential to improve the local control rates and reduce the risk of toxicity forlung cancer patients. However, the delivery of proton therapy is prone to uncertainties caused byanatomical changes and motion during the treatment and between the treatment fractions whichmay compromise its effectiveness. The dosimetric uncertainty of lung cancer proton therapy can beminimized t

In this review, the Basic and Translational Science Assembly of the European Respiratory Society provides an overview of the 2022 International Congress highlights. We discuss the consequences of respiratory events from birth until old age regarding climate change related alterations in air quality due to pollution caused by increased ozone, pollen, wildfires and fuel combustion as well as the inc

Background: Treatment guidelines recommend behaviour therapy (BT) for patients with Tourette syndrome (TS) and chronic tic disorder (CTD). However, BT is rarely accessible due to limited availability of trained therapists and long travel distances to specialist clinics. Internet-delivered BT has the potential of overcoming these barriers through remote delivery of treatment with minimal therapist

We summarize selected research reports from 2021 relevant to Tourette syndrome that the authors consider most important or interesting. The authors welcome article suggestions and thoughtful feedback from readers.

Background: Patient adherence is defined as the extent to which a patient complies with medical or health advice. At present, there is a lack of reliable and valid measures specifically designed to measure adherence to internet-delivered behavioral interventions. Objective: The objective of this study was to develop and psychometrically evaluate a novel measure of adherence to guided internet-deli

Background Cognitive behaviour therapy (CBT) is an effective treatment for obsessive-compulsive disorder (OCD) but access to CBT is limited. Internet-based CBT (ICBT) with therapist support is potentially a more accessible treatment. There are no randomized controlled trials testing ICBT for OCD. The aim of this study was to investigate the efficacy of ICBT for OCD in a randomized controlled trial

α-Synuclein aggregates constitute the pathology of Lewy body (LB) disease. Little is known about the effects of LB pathology in preclinical (presymptomatic) individuals, either as isolated pathology or coexisting with Alzheimer's disease (AD) pathology (β-amyloid (Aβ) and tau). We examined the effects of LB pathology using a cerebrospinal fluid α-synuclein-seed amplification assay in 1,182 cogniti

Background. A mathematical framework is presented for simultaneously quantifying and evaluating the trade-off between tumor control and late complications for risk-based radiation therapy (RT) decision-support. To demonstrate this, we estimate life years lost (LYL) attributable to tumor recurrence, late cardiac toxicity and secondary cancers for standard-risk pediatric medulloblastoma (MB) patient

The various structural components of the cortical degeneration of Alzheimer's disease were defined and graded. The severity of the degenerative process was thus mapped in different cortical areas where neuronal numbers and cortical width were also measured and compared with controls. Contrary to the general opinion that the degenerative process is rather uniformly diffuse, though accentuated in th

Part II of the European clinical guidelines for Tourette syndrome and other tic disorders (ECAP journal, 2011) provides updated information and recommendations for psychological interventions for individuals with tic disorders, created by a working group of the European Society for the Study of Tourette Syndrome (ESSTS). A systematic literature search was conducted to obtain original studies of ps

Why do we in the Western part of world today tend to believe in technology’s mythical promises rather than in folklore myths? Imaginaries of the future influence political subjects’ actions in the present and play a key role in composing the trajectory towards the future. I have critically applied this notion to the implementation of negative emission technologies in the climate-neutrality strateg

The deep-sea may be on the verge of becoming the latest frontier for resource extraction of critical metals and minerals in order to build renewable energy technologies such as electric vehicles. This thesis examines the narratives used by the deep-sea mining company The Metals Company to justify the extraction of polymetallic nodules from the seabed in the Clarion Clipperton Zone in the Pacific O

The figure of scenarios is frequently used in present-day climate science and plays a prominent role in the architecture of the IPCC Reports. In this work, I undertake a philosophical and critical investigation into the ontological, epistemological and temporal modalities of the figure of scenario. I do so by engaging with the term’s supra-scientific origins, with the history of its semantic alter

The UK government is legally bound to reach net zero greenhouse gas emissions by 2050 as part of its actions to address climate change. One prominent method of decarbonisation is carbon capture and storage (CCS), slated for deployment in two industrial clusters by the mid-2020s. Fossil fuel companies are the operator behind the rollout of this technology: given the historical reticence of these co

Emerging markets are becoming increasingly important in the global tourism sector, accounting for a significant portion of international tourist arrivals. Because of the constant changes that occur in emerging markets, their tourist behaviour and decision-making process vary from that of tourists from more established markets. In order to achieve tourism growth and face its challenges, the United

BACKGROUND: Most cerebral palsy (CP) cases have an unexplained etiology, but a role for environmental exposures has been suggested. One purported environmental risk factor is exposure to endocrine-disrupting pollutants specifically per- and polyfluoroalkyl substances (PFAS).OBJECTIVES: We investigated the association between prenatal PFAS exposures and CP in Swedish children.METHODS: In this case-