Background. We investigated how varying the treatment margin and applying hippocampal sparing and proton therapy impact the risk of neurocognitive impairment in pediatric medulloblastoma patients compared with current standard 3D conformal radiotherapy. Methods. We included 17 pediatric medulloblastoma patients to represent the variability in tumor location relative to the hippocampal region. Trea

BackgroundIn primary health care people with mental health needs are often overlooked or masked with physical complaints. It has been suggested that public health nurses lack sufficient knowledge when encountering people with mental health problems. Low levels of mental health literacy among professionals are associated with negative patient outcome. There is a need to understand public health nur

Body dysmorphic disorder (BDD) often starts in childhood, with most cases developing symptoms before age 18. Yet, BDD research has primarily focused on adults. We report the clinical characteristics of the world’s largest cohort of carefully diagnosed youths with BDD and focus on previously unexplored sex and age differences. We systematically collected clinical data from 172 young people with BDD

Background: Process evaluations are an important component in the interpretation and understanding of outcomes in trials. The Online Remote Behavioural Intervention for Tics (ORBIT) study is a randomized controlled trial evaluating the effectiveness of an Internet-delivered behavioural intervention (called BIP TIC) compared to an Internet-delivered education programme aimed at children and young p

Objective Behaviour therapy (BT) for Tourette's disorder (TD) and persistent (chronic) motor or vocal tic disorder (PTD) is rarely available. We evaluated the feasibility of adapting two existing BT protocols for TD/PTD (habit reversal training (HRT) and exposure and response prevention (ERP)) into a therapist-guided and parent-guided online self-help format. Design A pilot, single-blind, parallel

Indigenous populations often bore the brunt of Christian settler colonization resulting in marginalization, assimilation, Christianization, and cultural elimination. Most perpetrators of colonial injustices go unpunished and wrongdoings unacknowledged, barring the possibility of genuine international and national reconciliation for indigenous peoples. Major settler colonizer states have dark colon

Background: Little is known about the long-term effectiveness of behavioural therapy for tics. We aimed to assess the long-term clinical and cost-effectiveness of online therapist-supported exposure and response prevention (ERP) therapy for tics 12 and 18 months after treatment initiation. Methods: ORBIT (online remote behavioural intervention for tics) was a two-arm (1:1 ratio), superiority, sing

The aim of the article is to correlate grey and white matter changes and their topography to the results of modern methods for brain imaging such as CT, rCBF, PET, SPECT and NMR in Alzheimer's type of dementia. The findings are based on the study of a large material investigated thoroughly patho-anatomically. The findings are correlated with psychiatric and neurophysiologic follow-up studies. The

Values are a crucial aspect of human–nature relationships, and they play important roles in policies on land use and environmental management. However, our current decision-making systems tend to take inadequate account of the diversity of values associated with human relationships with nature. Instrumental, monetary values dominate the political systems following the Western neoliberal hegemony.

This study arises from an existential concern that there is an obliviousness in academia with regards to the recent eruption of the transhumanist movement–an ideological force imbued with potentially calamitous socioecological consequences. With the support from recent claims that the transhumanist ideology exerts powerful influence on Western politics, this study seeks to investigate how the tran

This work presents an automated method for comprehensively analyzing EPID images acquired for quality assurance of RapidArc® treatment delivery. In-house-developed software has been used for the analysis and long-term results from measurements on three linacs are presented.

Chile is positioning itself as a leader in the transition to green energy, particularly through its National Green Hydrogen Strategy, which aims to make Chile one of the world’s leading exporters of carbon-neutral hydrogen for energy and industrial applications. This thesis examines Chile’s green hydrogen policy from a political ecology perspective, in the context of 1) the Chilean state’s concept

Mass spectrometry (MS) and nuclear magnetic resonance (NMR) spectroscopy techniques have been used extensively for metabolite profiling. Although combining these two analytical modalities has the potential of enhancing metabolite coverage, such studies are sparse. In this study we test the hypothesis that combining the metabolic information obtained using liquid chromatography (LC) MS and 1H NMR s

Recension av Martin Gelin, Den vita stormen. Rasismens historia och USA:s fall

Recension av Carl-Göran Heidegren, Den högra handens tendens.

Recension av Jack Werner, Berättelsen om Ormen Friske.

BACKGROUND: From birth, infants orient preferentially to faces, and when looking at the face, they attend primarily to eyes and mouth. These areas convey different types of information, and earlier research suggests that genetic factors influence the preference for one or the other in young children.METHODS: In a sample of 535 5-month-old infant twins, we assessed eye (relative to mouth) preferenc

Den globala uppvärmningen medför att sannolikheten för extrema värmeböljor ökar i ett framtida klimat. Sommaren 2018 var en ögonöppnare för många i Sverige då den långvariga värmen medförde extrem torka och ett flertal skogsbränder. De mest sårbara i samhället drabbad av värmen, så som äldre, vuxna med kroniska sjukdomar och små barn, och ca 750 fler människor dog än vad som normalt förväntas undeThe summer of 2018 was a reality check for many when several heat waves made the temperature rise above normal in Sweden. Especially in urban areas, where heat can be stored more easily in the building materials, the temperature was extreme due to the creation of urban heat islands. Today these areas can be detected with a tool for mapping urban heat islands. The aim of this study is to examine h

Introduction: Glycolytic activity and hypoxia are associated with poor prognosis and radiation resistance. Including both the tumor uptake of 2-deoxy-2-[18 F]-fluorodeoxyglucose (FDG) and the proposed hypoxia tracer copper(II)diacetyl-bis(N4)-methylsemithio-carbazone (Cu-ATSM) in targeted therapy planning may therefore lead to improved tumor control. In this study we analyzed the overlap between s