Creating protein aggregates with the ability to form thiol-specific covalent bonds through genetic modification of amelogenin
Amelogenin is an enamel matrix protein which participates in the formation of dental enamel, the hardest tissue in the human body. The protein participates in this process by orienting the mineral crystals which make up the enamel and several proteolytic products from amelogenin also affect the dental enamel during its maturation. The protein is mostly hydrophobic with a hydrophilic region at the