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Increased production of the TrkB protein tyrosine kinase receptor after brain insults

The protein-tyrosine kinases Trk, TrkB, and TrkC are signal-transducing receptors for a family of neurotrophic factors known as the neurotrophins. Here we show that seizures induced by hippocampal kindling lead to a rapid, transient increase of trkB mRNA and protein in the hippocampus. TrkB is a component of a high affinity receptor for brain-derived neurotrophic factor (BDNF). No change was detec

Online High Resolution Stochastic Radiation Radar Imaging using Sparse Covariance Fitting

Stochastic radiation radar (SRR) systems allow for the forming of radar images by transmitting stochastic signals to form the stochastic radiation field and thereby increase the target observation information to achieve high resolution imaging. In this paper, we examine the use of the online SParse Iterative Covariance-based Estimation (SPICE) algorithm to suppress the noise and improve the operat

In-situ SEM study of fracture of an ultrathin Al-foil-modelling of the fracture processes

Fracture behavior of an ultra thin aluminium foil was studied. For very short crack lengths, fracture has been followed in the scanning electron microscope (SEM) with a tensile stage. A single edge notched tension specimen was used. Crack length and applied load during the crack growth were measured. These results have been used to calculate fracture strength using linear elastic fracture mechanicFracture behavior of an ultra thin Aluminium foil was studied. For very short crack lengths, fracture has been followed in the scanner electronic microscope (SEM) with a tensile stage. A single edge notched tension specimen was used. Crack length and applied load during the crack growth were measured. These results have been used to calculate fracture strength using linear elastic fracture mechani

Strain-driven corrosion crack growth - A pilot study of intergranular stress corrosion cracking

This work proposes a model for corrosion driven crack growth. The model poses a moving boundary problem, where a chemical attack removes material from the body. The rate of the chemical attack is a function of the strain along the body surface. No crack growth criterion is needed for the analysis. A finite strain formulation is used and the material model is assumed hyperelastic. The problem is st

Effects of cytochrome P450 inhibitors on EDHF-mediated relaxation in the rat hepatic artery

1. The possibility that the endothelium-derived hyperpolarising factor (EDHF) in the rat hepatic artery is a cytochrome P450 mono-oxygenase metabolite of arachidonic acid was examined in the present study. In this preparation, acetylcholine elicits EDHF-mediated relaxations in the presence of the nitric oxide (NO) synthase and cyclo-oxygenase inhibitors N(ω)-nitro-L-arginine (L-NOARG) and indometh