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Exhaust volume dependency of turbocharger turbine design for a heavy duty otto cycle engine

This study is considering turbocharger turbine performance at "on-engine" conditions with respect to turbine design variables and exhaust manifold volume. The highly unsteady nature of the internal combustion engine will result in a very wide range of turbine operation, far from steady flow conditions. As most turbomachinery design work is conducted at steady state, the influence of the chosen tur

Local adaptation studies and conservation : Parasite-host interactions between the endangered freshwater mussel Unio crassus and its host fish

Parasite-host interactions can involve strong reciprocal selection pressure, and may lead to locally adapted specializations. The highly threatened unionoid mussels are temporary parasites on fish, but local adaptation has not yet been investigated for many species. Patterns of local adaptation of one of Europe's most threatened unionoids, the thick-shelled river mussel (Unio crassus) were investi

The expression of mental states in a humanoid robot

We explore to what degree movement together with facial features in a humanoid robot, such as eyes and mouth, can be used to convey mental states. Several animation variants were iteratively tested in a series of experiments to reach a set of five expressive states that can be reliably expressed by the robot. These expressions combine biologically motivated cues such as eye movements and pupil dil

Neonatal alloimmune thrombocytopaenia associated with maternal HLA antibodies

Neonatal alloimmune thrombocytopaenia (NAIT) generally results from platelet opsonisation by maternal antibodies against fetal platelet antigens inherited from the infant's father. Newborn monochorionic twins presented with petechial haemorrhages at 10 hours of life, along with severe thrombocytopaenia. Despite the initial treatment with platelet transfusions and intravenous immunoglobulin, they b

Scalable performance, efficiency and thermal models for electric drive components used in powertrain simulation and optimization

A methodology for designing and scaling the performance and thermal characteristics of electric powertrain components is presented. This methodology is aimed at finding optimum component combinations based on a set of requirements. Both drive-cycle performance and specific operating modes such as curb-climbing and maximum wheel speed are considered. This allows the selection of electrical machine

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Titan, Demon and Genius in the Poetical Work of Mihai Eminescu is a book that furthers on the interpretation of the most representative Eminescu’s poems and also of his lyrical theatre. Besides, a special chapter is dedicated to the cultural context of the second half of the 19th century and another one records the literary works inspired by Eminescu’s works and personality throughout the 20th cen

Effect of spanwise variation of chord on the performance of a turbine cascade

This paper compares the aerodynamic performance of two cascade designs, viz.: -constant-chord and varying-chord. The varying-chord design is typical of industrial gas turbines and steam turbine stators in order to reduce manufacturing costs. The present study aims to increase the understanding of the implications of this manufacturing constraint on the aerodynamics of the stator. Experiments are c

Care professional's experiences about using Liverpool Care Pathway in end-of-life care in residential care homes

Background: Residential care homes (RCHs) play an important role in end-of-life care, being the most common place of death for elderly people in several European countries. Care pathways such as the Liverpool Care Pathway for the Dying Patient (LCP) are used to improve and ensure quality care at the end of life. There is a lack of scientific evidence supporting the use of care pathways. Design: A

CD44 interacts with HIF-2α to modulate the hypoxic phenotype of perinecrotic and perivascular glioma cells

Hypoxia-inducible factors enhance glioma stemness, and glioma stem cells have an amplified hypoxic response despite residing within a perivascular niche. Still, little is known about differential HIF regulation in stem versus bulk glioma cells. We show that the intracellular domain of stem cell marker CD44 (CD44ICD) is released at hypoxia, binds HIF-2α (but not HIF-1α), enhances HIF target gene ac

Risk management for maintenance of district heating networks

Underground infrastructure such as buried district heating pipes are difficult to inspect. The methods available to assess the status of the district heating pipes are often both expensive and do not provide enough evidence to determine the condition of the pipelines. This paper discusses how utilities systematically can work with risk assessments and risk classification to plan the maintenance an

When prices don’t steer – mimicking ambitious carbon pricing with energy performance standards

Pricing carbon is often considered to be the cornerstone of any climate policy and, at least in economic theory, it is the only policy intervention required to reach an optimal level of mitigation. In practice, various market and behavioural failures, as well as political barriers, necessitate a policy mix that also encompasses policies to induce energy efficiency and stimulate the up-take of rene

Explaining municipal audit costs in Sweden : Reconsidering the political environment, the municipal organisation and the audit market

With the purpose of explaining professional audit costs in Swedish municipalities, we hypothesised that audit costs are partly driven by various signalling and monitoring incentives in order to manage stakeholder relationships. Our model of the determinants of audit costs was tested on data from Swedish municipalities, thus extending the study of audit costs to political organisations in a Scandin

Heterogeneous Association of Alzheimer's Disease-Linked Amyloid-β and Amyloid-β Protein Precursor with Synapses

Alzheimer's disease (AD) is increasingly viewed as a disease of synapses. Loss of synapses correlates better with cognitive decline than amyloid plaques and neurofibrillary tangles, the hallmark neuropathological lesions of AD. Soluble forms of amyloid-β (Aβ) have emerged as mediators of synapse dysfunction. Aβ binds to, accumulates, and aggregates in synapses. However, the anatomical and neurotra

Investigating the evolving microstructure of lithium metal electrodes in 3D using X-ray computed tomography

The growth of electrodeposited lithium microstructures on metallic lithium electrodes has prevented their use in rechargeable lithium batteries due to early performance degradation and safety implications. Understanding the evolution of lithium microstructures during battery operation is crucial for the development of an effective and safe rechargeable lithium-metal battery. This study employs bot

Cold adaptation drives variability in needle structure and anatomy in Pinus sylvestris L. along a 1,900 km temperate-boreal transect

Occupancy of cold habitats by evergreen species requires structural modification of photosynthetic organs for stress resistance and longevity. Such modifications have been described at interspecific level, while intraspecific variation has been underexplored. To identify structural and anatomical traits that may be adaptive in cold environments, we studied intraspecific variability of needles of S

Variation in maturity-onset diabetes of the young genes influence response to interventions for diabetes prevention

Context: Variation in genes that cause maturity-onset diabetes of the young (MODY) has been associated with diabetes incidence and glycemic traits. Objectives: This study aimed to determine whether genetic variation in MODY genes leads to differential responses to insulin-sensitizing interventions. Design and Setting: This was a secondary analysis of a multicenter, randomized clinical trial, the D