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Grants Hjelt foundation

Published 31 January 2014 Five researchers from Lund University and the University of Geneva has bedn granted altogether 200 000 Euro from Bo & Kerstin Hjelt Foundation for type 2 diabetes. Dr Jens Lagerstedt, Lund University: "Zinc transporter ZnT8 and type 2 diabetes" (€50 000)Dr Jonathan Esguerra, Lund University: "Characterization of non-coding RNAs in the pancreatic islets of Langerhans and i

https://www.ludc.lu.se/article/grants-hjelt-foundation - 2025-04-21

Epigenetic changes could explain type 2 diabetes

Published 7 March 2014 People with type 2 diabetes have epigenetic changes on their DNA that healthy individuals do not have. This has been shown in a major study by researchers at Lund University. The researchers also found epigenetic changes of a large number of genes that contribute to reduced insulin production. “This shows that the risk of developing type 2 diabetes is not only genetic, but a

https://www.ludc.lu.se/article/epigenetic-changes-could-explain-type-2-diabetes - 2025-04-21

Nanoparticles cause cancer cells to commit suicide

Published 3 April 2014 Using magnetically controlled nanoparticles to force tumour cells to ‘commit suicide’ sounds like science fiction, but could be a future part of cancer treatment. “The clever thing about the technique is that we can target selected cells without harming surrounding tissue”, said Professor Erik Renström from Lund University. In brief, the technique involves getting the nanopa

https://www.ludc.lu.se/article/nanoparticles-cause-cancer-cells-commit-suicide - 2025-04-21

Cystic fibrosis and diabetes link explained

Published 2 June 2014 “The increased risk of diabetes has previously been explained by the fact that cystic fibrosis causes damage to the pancreas, where the blood-sugar regulating hormone insulin is produced. We are the first research group to show that the mutated gene that causes cystic fibrosis also plays an important role in the release of insulin. The risk of diabetes is not only explained b

https://www.ludc.lu.se/article/cystic-fibrosis-and-diabetes-link-explained - 2025-04-21

100 millions to strengthen the Swedish life science sector

Published 10 June 2014 The Swedish Innovation Agency, VINNOVA, has granted 100 MSEK to the Strategic Innovation Programme, SIO Chronic Diseases, with the overall aim to create better health and increased growth in Sweden. If Sweden is to remain competitive on the global life science stage, the opportunities for turning research results into innovations providing growth and benefit for patients nee

https://www.ludc.lu.se/article/100-millions-strengthen-swedish-life-science-sector - 2025-04-21

Study of identical twins reveal type 2 diabetes clues

Published 6 October 2014 By studying identical twins, researchers from Lund University in Sweden have identified mechanisms that could be behind the development of type 2 diabetes. This may explain cases where one identical twin develops type 2 diabetes. The study involved 14 pairs of identical twins in Sweden and Denmark. One twin had type 2 diabetes and the other was healthy.“Twins are a good mo

https://www.ludc.lu.se/article/study-identical-twins-reveal-type-2-diabetes-clues - 2025-04-21

Lagerstedt and Stenkula receive Novo Seed Grant

Published 21 January 2015 Antidiabetics that also provide cardiovascular benefit is a key unmet need in diabetes treatment. ApoA-l is a protein shown to have both glucose lowering and cholesterol-lowering effects and has been investigated by Jens Lagerstedt and Karin Stenkula for its therapeutic potential. They have now received 2,5 million Danish kroner from the Novo Seeds for taking innvoation a

https://www.ludc.lu.se/article/lagerstedt-and-stenkula-receive-novo-seed-grant - 2025-04-21

New method measures the risk of type 2 diabetes in blood

Published 31 March 2016 Researchers at Lund University in Sweden have found a new type of biomarker that can predict the risk of type 2 diabetes, by detecting epigenetic changes in specific genes through a simple blood test. “This could motivate a person at risk to change their lifestyle”, says Karl Bacos, researcher in epigenetics at Lund University. The results are published today in Nature Comm

https://www.ludc.lu.se/article/new-method-measures-risk-type-2-diabetes-blood - 2025-04-21

Decreased cell death and increased insulin production in pancreatic beta cells with genome edit by CRISPR/Cas9

Published 1 December 2016 Using the CRISPR/Cas9 “gene scissors” researchers at Lund University Diabetes Centre in Sweden have managed to “turn off” an enzyme that proved to play a key role in the regulation of the diabetes-associated TXNIP gene. The results are decreased cell death and increased insulin production in the genetically modified pancreatic beta cells. In a recent study, researchers ha

https://www.ludc.lu.se/article/decreased-cell-death-and-increased-insulin-production-pancreatic-beta-cells-genome-edit-crisprcas9 - 2025-04-21

Investments in epigenetics to combat diabetes

Published 14 December 2016 Charlotte Ling, professor of epigenetics at the Department of Clinical Sciences in Malmö, Lund University Diabetes Centre, Sweden, has been awarded the European Research Council’s Consolidator Grant. The funding of EUR 2 million over five years will be used to develop new methods to improve prediction, prevention and treatment of type 2 diabetes. Charlotte Ling is a pion

https://www.ludc.lu.se/article/investments-epigenetics-combat-diabetes - 2025-04-21

Beat-DKD An Innovative Medicines Initiative Project for Precision Medicine in DKD

Published 6 February 2017 BEAt-DKD (“Biomarker Enterprise to Attack Diabetic Kidney Disease”), a unique public private partnership funded by the Innovative Medicines Initiative (IMI), member companies from the European Federation of Pharmaceutical Industries and Associations (EFPIA), the Juvenile Diabetes Research Foundation (JDRF) and the state of Switzerland has announced the launch of a 5-year

https://www.ludc.lu.se/article/beat-dkd-innovative-medicines-initiative-project-precision-medicine-dkd - 2025-04-21

Prize awarded to research in zebrafish that could lead to new treatments for diabetes

Published 5 March 2019 In his research in zebrafish, Olov Andersson of Karolinska Institutet strives to generate insulin-producing cells and new treatment methods for diabetes. This has led to his selection as a recipient of the Leif C. Groop award for outstanding research, awarded by the Lund University Diabetes Centre and sponsored by Novo Nordisk Sweden. "It is a quick process to generate genet

https://www.ludc.lu.se/article/prize-awarded-research-zebrafish-could-lead-new-treatments-diabetes - 2025-04-21

Nordic network of metabolic researchers

Published 4 April 2019 A two-days seminar gathered some 70 researchers from the University of Bergen, the Institute for Molecular Medicine in Finland (FIMM) and Lund University Diabetes Centre. - We wanted to strengthen the bonds that already exist and in the future create a Nordic network of metabolic researchers, says Ola Hansson who organized the meeting. Kay Prüfer from Max-Planck Institute in

https://www.ludc.lu.se/article/nordic-network-metabolic-researchers - 2025-04-21

Screening for T1D and celiac disease

Published 5 April 2019 In Skåne, newborn babies can be screened for type 1 diabetes and celiac disease (gluten intolerance). To raise awareness about the screening we will be running an information campain on all commuter trains and busses in Skåne during week 15 and 19. Screening för typ 1-diabetes och celiaki Children found to be at risk are eligable to participate in our prevention studies POIn

https://www.ludc.lu.se/article/screening-t1d-and-celiac-disease - 2025-04-21

3rd Joint EASD Islet Study Group and Beta-Cell Workshop

Published 15 April 2019 The 3rd Joint EASD Islet Study Group and Beta-Cell Workshop gathered experts in islet cell biology - mainly beta cells - ranging from development to function and with a focus on both type 1- and type 2-diabetes. Top from left: Jonathan Esguerra, Lena Eliasson, Elaine Cowan, Clair Lyons, Amaya Lopez and Hindrik Mulder. In the front: Alexander Hamilton and Malin Fex. This yea

https://www.ludc.lu.se/article/3rd-joint-easd-islet-study-group-and-beta-cell-workshop - 2025-04-21

Screening finds children at high risk for type 1 diabetes and celiac disease

Published 17 April 2019 In Skåne, newborn babies can be screened for type 1 diabetes and celiac disease (gluten intolerance). More than expected have been found to have an increased risk of developing these diseases, and about thirty children have already been recruited for research studies aimed at lowering this risk. The oral insulin is mixed with the food. Photo: Johan Bävman Large-scale screen

https://www.ludc.lu.se/article/screening-finds-children-high-risk-type-1-diabetes-and-celiac-disease - 2025-04-21

Diabetes researcher elected to the British Royal Society

Published 18 April 2019 David Nicholls, professor emeritus of Mitochondrial Physiology at the Buck Institute in Novato, California and mentor at the Lund University Diabetes Centre, has become a member of the British Royal Society. The society’s fellows include many of the world’s most eminent scientists. “I feel immensely honoured!” says David Nicholls. David Nicholls knew from a very early age t

https://www.ludc.lu.se/article/diabetes-researcher-elected-british-royal-society - 2025-04-21

How lifestyle affects our genes

Published 23 April 2019 In the past decade, knowledge of how lifestyle affects our genes, a research field called epigenetics, has grown exponentially. Researchers at the Lund University Diabetes Centre have summarised the state of scientific knowledge within epigenetics linked to obesity and type 2 diabetes in a review article published in the scientific journal Cell Metabolism. The epigenome is

https://www.ludc.lu.se/article/how-lifestyle-affects-our-genes - 2025-04-21

Gestational diabetes in India and Sweden

Published 26 April 2019 Indian women are younger and leaner than Swedish women when they develop gestational diabetes, a new study from Lund University Diabetes Centre shows. The researchers also found a gene that increases the risk of gestational diabetes in Swedish women, but which, on the contrary, turned out to have a protective effect in Indian women. " The study show that personalized treatm

https://www.ludc.lu.se/article/gestational-diabetes-india-and-sweden - 2025-04-21

LUDC researcher awarded

Published 3 May 2019 Helena Elding Larsson, senior physician and associate professor at Lund University, has been awarded 1,1 million SEK from Odd Fellow Orden Sweden. Helena Elding Larsson has been awarded a gift as support for a research project aiming to study if oral insulin given to children from 4-7 months of age to 3 years, with high genetic risk, can prevent the development of beta cell au

https://www.ludc.lu.se/article/ludc-researcher-awarded - 2025-04-21