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A Hierarchical Approach Using Marginal Summary Statistics for Multiple Intermediates in a Mendelian Randomization or Transcriptome Analysis

By anna [dot] axmon [at] med [dot] lu [dot] se (Anna Axmon) - published 8 July 2021 Photo: Pixabay / Arek Socha We propose to extend our previous approach for the joint analysis of marginal summary statistics to incorporate prior information via a hierarchical model (hJAM). Read the paper at https://doi.org/10.1093/aje/kwaa287

https://www.lupop.lu.se/article/hierarchical-approach-using-marginal-summary-statistics-multiple-intermediates-mendelian - 2025-03-12

Assessing the external validity of the VALIDATE-SWEDEHEART trial

By anna [dot] axmon [at] med [dot] lu [dot] se (Anna Axmon) - published 9 July 2021 Photo: Pixabay / Ben Kerckx The VALIDATE-SWEDEHEART trial was a registry-based randomized trial comparing bivalirudin and heparin in patients with acute myocardial infarction undergoing percutaneous coronary intervention. It showed no differences in mortality at 30 or 180 days. This study examines how well the tria

https://www.lupop.lu.se/article/assessing-external-validity-validate-swedeheart-trial - 2025-03-12

Estimating perceived parental substance use disorder: Using register data to adjust for non-participation in survey research

By anna [dot] axmon [at] med [dot] lu [dot] se (Anna Axmon) - published 10 July 2021 Photo: Pixabay / Ralf Kunze Aims: To estimate the prevalence of parental substance use disorder (PSUD) in the general population based on young adults' reports adjusted for non-participation using register-based indicators of PSUD. Read the paper at https://europepmc.org/article/med/33878599

https://www.lupop.lu.se/article/estimating-perceived-parental-substance-use-disorder-using-register-data-adjust-non-participation - 2025-03-12

Integrating data from multiple Finnish biobanks and national health-care registers for retrospective studies: Practical experiences

By anna [dot] axmon [at] med [dot] lu [dot] se (Anna Axmon) - published 11 July 2021 A large cohort, consisting of versatile individual-level phenotype and genotype data, can be constructed by integrating data from several biobanks and health data registers in Finland. Co-operation with biobanks is straightforward. However, long time periods need to be reserved when biobank resources are linked wi

https://www.lupop.lu.se/article/integrating-data-multiple-finnish-biobanks-and-national-health-care-registers-retrospective-studies - 2025-03-12

How to design a registry for undiagnosed patients in the framework of rare disease diagnosis: suggestions on software, data set and coding system

By anna [dot] axmon [at] med [dot] lu [dot] se (Anna Axmon) - published 12 July 2021 Photo: flickr / agilemktg1 About 30 million people in the EU and USA, respectively, suffer from a rare disease. Driven by European legislative requirements, national strategies for the improvement of care in rare diseases are being developed. Read the paper at https://ojrd.biomedcentral.com/articles/10.1186/s13023

https://www.lupop.lu.se/article/how-design-registry-undiagnosed-patients-framework-rare-disease-diagnosis-suggestions-software-data - 2025-03-12

A Canadian Prospective Study of Linkage of Randomized Clinical Trial to Cancer and Mortality Registry Data

By anna [dot] axmon [at] med [dot] lu [dot] se (Anna Axmon) - published 13 July 2021 Photo: Pixabay / Colin Behrens In a prospective study, we sought to determine acceptability of linkage of administrative and clinical trial data among Canadian patients and Research Ethics Boards (REBs). The goal is to develop a more harmonized approach to data, with potential to improve clinical trial conduct thr

https://www.lupop.lu.se/article/canadian-prospective-study-linkage-randomized-clinical-trial-cancer-and-mortality-registry-data - 2025-03-12

Umeå universitet söker forskningssamordnare med fokus på processer för biobankers forskningsdata

By anna [dot] axmon [at] med [dot] lu [dot] se (Anna Axmon) - published 23 June 2021 Du kommer att samla in och ställa samman kunskap om forskningsdata och dess hantering i biobankskohorter, såväl i Umeå som nationellt. Målet är att peka ut förbättringsområden, för förbättrade och förenklade flöden för forskningen. Parallellt kommer du att arbeta med att ge konkret stöd till forskare inom olika bi

https://www.lupop.lu.se/article/umea-universitet-soker-forskningssamordnare-med-fokus-pa-processer-biobankers-forskningsdata - 2025-03-12

Ny studie: Resursfördelning och utfall inom intensivvården

By anna [dot] axmon [at] med [dot] lu [dot] se (Anna Axmon) - published 24 June 2021 Photo: Pixabay / Leo2014 Detta forskningsprojekt syftar till att undersöka om det finns patientgrupper som behöver extra mycket resurser, och vad som i så fall skiljer dessa patienter från patienter som inte behöver lika stora resurser. Läs mer om studien på https://www.lupop.lu.se/resursfordelning-och-utfall-inom

https://www.lupop.lu.se/article/ny-studie-resursfordelning-och-utfall-inom-intensivvarden - 2025-03-12

Ny studie: Maskininlärning för bättre diagnostik och behandling av vuxna patienter som söker sjukvård på grund av andningssvårigheter

By anna [dot] axmon [at] med [dot] lu [dot] se (Anna Axmon) - published 2 August 2021 Photo: Pixabay / Gerd Altmann Vi avser i detta projekt undersöka om vi med maskininlärning (artificiell intelligens, AI) kan träna en dator att känna igen mönster i akutpatienters data, såsom tidigare sjukdomar, läkemedelsanvändning, undersökningsresultat och sociala faktorer, för att sedan kunna förutsäga vilken

https://www.lupop.lu.se/article/ny-studie-maskininlarning-battre-diagnostik-och-behandling-av-vuxna-patienter-som-soker-sjukvard-pa - 2025-03-12

New position as assistant researcher in epidemiology

By anna [dot] axmon [at] med [dot] lu [dot] se (Anna Axmon) - published 2 August 2021 Photo: Pixabay / Brian Merrill We are looking for an assistant researcher in Epidemiology for work that is linked to a thematic collaborative initiative on improved pandemic preparedness that has received internal funding from Lund University 2021 – 2024. The initiative is a truly interdisciplinary collaboration

https://www.lupop.lu.se/article/new-position-assistant-researcher-epidemiology - 2025-03-12

The first experiences of implementation of the Swedish tonsil register in Denmark

By anna [dot] axmon [at] med [dot] lu [dot] se (Anna Axmon) - published 4 August 2021 Photo: Pixabay / Sasin Tipchai Tonsil surgery is a daily procedure at Ear, Nose and Throat (ENT) departments as well as ENT practices. Despite national tonsil guidelines in Denmark, no national survey has been introduced. Read the full paper here.

https://www.lupop.lu.se/article/first-experiences-implementation-swedish-tonsil-register-denmark - 2025-03-12

Nordic Health Registry-Based Research: A Review of Health Care Systems and Key Registries

By anna [dot] axmon [at] med [dot] lu [dot] se (Anna Axmon) - published 5 August 2021 Photo: Wikimedia Commons / Søren Sigfusson The Nordic countries are Denmark, Finland, Iceland, Norway, and Sweden and comprise a total population of approximately 27 million. The countries provide unique opportunities for joint health registry-based research in large populations with long and complete follow-up,

https://www.lupop.lu.se/article/nordic-health-registry-based-research-review-health-care-systems-and-key-registries-0 - 2025-03-12

Covid-forskning från Lunds universitet

By anna [dot] axmon [at] med [dot] lu [dot] se (Anna Axmon) - published 5 August 2021 Image from pixabay / pearson0612 En studie rörande effekter av åldersspecifika rekommendationer i samband med Covid-19-pandemin, i vilken flera forskare från Lunds universitet medverkat, har nyligen publicerats "pre-print" och i samband med detta uppmärksammats i diverse media. Preprint-artikeln finns att läsa på

https://www.lupop.lu.se/article/covid-forskning-fran-lunds-universitet - 2025-03-12

The impact of COVID-19 pandemic on vascular registries and clinical trials

By anna [dot] axmon [at] med [dot] lu [dot] se (Anna Axmon) - published 11 August 2021 Photo: Pixabay / Arek Socha Quality improvement programs and clinical trial research experienced disruption due to the coronavirus disease 2019 (COVID-19) pandemic. Vascular registries showed an immediate impact with significant declines in second-quarter vascular procedure volumes witnessed across Europe and th

https://www.lupop.lu.se/article/impact-covid-19-pandemic-vascular-registries-and-clinical-trials - 2025-03-12

Open position: Professor at the Department of Public Health

By anna [dot] axmon [at] med [dot] lu [dot] se (Anna Axmon) - published 11 August 2021 he Department of Public Health, Faculty of Health, Aarhus University invites applications for one to three positions as full professor in research fields of relevance for the Department of Public Health including research related to Biostatistics, Epidemiology, General Practice, Nursing, Public Health Science, S

https://www.lupop.lu.se/article/open-position-professor-department-public-health - 2025-03-12

Accurate population-based model for individual prediction of colon cancer recurrence

By anna [dot] axmon [at] med [dot] lu [dot] se (Anna Axmon) - published 12 August 2021 Photo: Pixabay / Colin Behrens Prediction models are useful tools in the clinical management of colon cancer patients, particularly when estimating the recurrence rate and, thus, the need for adjuvant treatment. However, the most used models (MSKCC, ACCENT) are based on several decades-old patient series from cl

https://www.lupop.lu.se/article/accurate-population-based-model-individual-prediction-colon-cancer-recurrence - 2025-03-12

Utredning föreslår ny myndighet för att samla digital infrastruktur

By anna [dot] axmon [at] med [dot] lu [dot] se (Anna Axmon) - published 12 August 2021 Photo: Pixabay / Gerd Altmann Den 11 augusti höll regeringen pressträff för att presentera resultatet av utredningen Organisation, styrning och finansiering av forskningsinfrastruktur. Utredningen har letts av Tobias Krantz och föreslår olika sätt att utveckla och stärka svensk forskningsinfrastruktur, bland ann

https://www.lupop.lu.se/article/utredning-foreslar-ny-myndighet-att-samla-digital-infrastruktur - 2025-03-12

Are responders to patient health surveys representative of those invited to participate?

By anna [dot] axmon [at] med [dot] lu [dot] se (Anna Axmon) - published 16 August 2021 An analysis of the Patient-Reported Outcome Measures Pilot from the Australian Orthopaedic Association National Joint Replacement Registry Read the paper at https://journals.plos.org/plosone/article?id=10.1371/journal.pone.02541…

https://www.lupop.lu.se/article/are-responders-patient-health-surveys-representative-those-invited-participate - 2025-03-12

Coding practice in national and regional kidney biopsy registries

By anna [dot] axmon [at] med [dot] lu [dot] se (Anna Axmon) - published 16 August 2021 Kidney biopsy registries all over the world benefit research, teaching and health policy. Comparison, aggregation and exchange of data is however greatly dependent on how registration and coding of kidney biopsy diagnoses are performed. This paper gives an overview over kidney biopsy registries, explores how the

https://www.lupop.lu.se/article/coding-practice-national-and-regional-kidney-biopsy-registries - 2025-03-12