Filetype
Smoking is widely regarded as a risk factor for type 2 diabetes because nicotine contributes to insulin resistance by desensitizing the insulin receptors in muscle, liver, or fat. Little is known, however, about the immediate regulation of islet hormonal output by nicotine, an agonist of ionotropic cholinergic receptors. We investigated this by imaging cytosolic Ca2+ dynamics in mouse and human is
Acquired von Willebrand syndrome (AVWS) is a rare condition characterized by an acquired functional and/or absolute deficiency of the von Willebrand factor (VWF) protein. The absence of widely accepted diagnostic criteria has hampered accurate estimates of incidence and prevalence, which are largely currently unknown. As bleeding symptoms are not included in the most widely used definitions, AVWS
Privacy-preserving blueprint schemes (Kohlweiss et al., EUROCRYPT’23) offer a mechanism for safeguarding user’s privacy while allowing for specific legitimate controls by a designated auditor agent. These schemes enable users to create escrows encrypting the result of evaluating a function y=P(t,x), with P being publicly known, t a secret used during the auditor’s key generation, and x the user’s
We present a superconducting cavity-coupled double quantum dot (DQD) photodiode that achieves a maximum photon-to-electron conversion efficiency of 25% in the microwave domain. With a higher-quality-factor cavity and improved device design to prevent photon leakages through unwanted pathways, our device measures microwave signals down to the 100-aW power level and achieves sensitivity to probe mic
Purpose: The aim of this study was to evaluate the feasibility and mid-term results of combining polytetrafluoroethylene (PTFE)-based iliac limbs, having a short dilator tip, with a polyester (Dacron)-based bifurcated component during a fenestrated endovascular aortic repair (FEVAR).Materials and methods: All patients who underwent a FEVAR procedure in a single tertiary center were screened for in
Para Alpine skiing is one of the largest sports at the Paralympic Winter Games. Recent studies report high injury rates in this sport. However, limited evidence exists regarding sport-specific injury characteristics, which is essential for targeted prevention. The aim of this study was to describe the overall incidence proportion and incidence of injuries reported by athletes participating in Alpi
Several studies have demonstrated strong agreement between routine clinical visual assessment and quantification, suggesting that quantification approaches could support assessment by less experienced readers or in challenging cases. However, all studies to date have implemented a retrospective case collection, and challenging cases were generally underrepresented. Methods: We included all partici
Background: Inadequate health literacy increases medical costs and leads to poor health outcomes. However, there is a paucity of empirical evidence of such associations in sub-Saharan Africa. This study investigates how the household cost of malaria in children under five in Ghana varies based on different levels of health literacy. Methods: A cross-sectional survey involving 1270 caregivers of ch
Purpose: To evaluate a new analytical estimator for R1 and apparent proton density (𝐴) from short-TR dual flip angle data which does not rely on the small flip angle approximation and can thus be applied to a broader range of data, especially where relatively large flip angles are needed to achieve sufficient T1-weighting for R1 estimation.Theory and Methods: A rational approximation of the Ernst
The purpose of this study is to investigate tourists’ behavioral intentions when selecting LHA for stays, considering the effects of the Attitude-Social Influence‑Efficacy Model, social identity theory, and accommodation attributes to predict guest behavior Applying a quantitative research design, questionnaire survey, and structural equation modeling for analyzing the data, the results revealed t
This paper studies how national welfare-state institutions influenced the positions states took on the social rights of refugees during the negotiation, adoption, and ratification of the 1951 United Nations Convention Relating to the Status of Refugees. Through an analysis of the drafting process and the reservations and interpretative declarations states issued when rat-ifying the Convention, the
BACKGROUND: Minimally invasive surgery is rapidly expanding globally, yet there is insufficient knowledge of how to scale this technology safely and equitably across diverse health systems. We aimed to identify health-system factors associated with safe implementation of minimally invasive surgery globally, using minimally invasive cholecystectomy as a tracer procedure.METHODS: We conducted a mult
This article explores how quantitative organological analysis can be implemented alongside historical musicology to help stimulate creativity in performance practice while promoting a diversity of timbre that is often lost amidst the hegemonic propagation of homogenized, normalized modern musical instruments. The tuba family provides an insightful case study demonstrating how the history and devel
Chickenpox is a highly contagious viral infection caused by varicella-zoster virus (VZV) whose clinical manifestations mimic mpox posing challenges for diagnosis without laboratory confirmation. Here, we investigated VZV among the mpox-suspected cases, May to October 2022, in Ethiopia. Samples were collected from 202 mpox-suspected cases in 11 of Ethiopia’s 14 regions and screened for mpox virus b
In this thesis, we evaluate the side-channel security of the NIST HQC post-quantum cryptosystem by analysing the official FPGA decapsulation implementation. A hardware wrapper was created to interact with the HQC decapsulation modules, enabling ciphertext decapsulation with precise power trace capturing using a ChipWhisperer CW305 and Husky setup. A dataset with 20k power traces was generated from
The writings of the Austrian novelist and essayist Robert Musil provide sociology with vital problems and reflections. Indeed, Musil, not least in the novel The Man without qualities, introduces discussions that extend conventional and recurrent understanding of modernity – sociology’s general object of analysis. The paper focuses on three major sets of questions in Musil’s work: 1) the shapelessnThe writings of the Austrian novelist and essayist Robert Musil provide sociologywith vital problems and reflections. Indeed, Musil, not least in the novel The Manwithout qualities, introduces discussions that extend conventional and recurrentunderstanding of modernity – sociology’s general object of analysis. The paperfocuses on three major sets of questions in Musil’s work: 1) the shapelessness
