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Phylogenetic generic classification of parmelioid lichens (Parmeliaceae,Ascomycota) based on molecular, morphological and chemical evidence.

Parmelioid lichens are a diverse and ubiquitous group of foliose lichens. Generic delimitation in parmelioid lichens has been in a state of flux since the late 1960s with the segregation of the large, heterogeneous genus Parmelia into numerous smaller genera. Recent molecular phylogenetic studies have demonstrated that some of these new genera were monophyletic, some were not, and others, previous

Evaluation of the prognostic significance of MSMB and CRISP3 in prostate cancer using automated image analysis.

Despite prostate cancer being the most frequent cancer in men in the Western world, tissue biomarkers for predicting disease recurrence after surgery have not been incorporated into clinical practice. Our group has previously identified β-microseminoprotein (MSMB) and cysteine-rich secretory protein-3 (CRISP3) as independent predictors of biochemical recurrence after radical prostatectomy. The pur

Potentials for prosperity without growth: Ecological sustainability, social inclusion and the quality of life in 38 countries

Recent contributions to ecological economics and related social sciences indicate that issues such as climate change, resource depletion and environmental degradation cannot be effectively addressed under conditions of continued economic growth. This paper aims at empirically identifying structural potentials and policy challenges for prosperity at scaleswhere economic development remainswithin ec

The AAA(+) motor complex of subunits CobS and CobT of cobaltochelatase visualized by single particle electron microscopy.

Cobalamins belong to the tetrapyrrole family of prosthetic groups(.) The presence of a metal ion is a key feature of these compounds. In the oxygen-dependent (aerobic) cobalamin biosynthetic pathway, cobalt is inserted into a ring-contracted tetrapyrrole called hydrogenobyrinic acid a,c-diamide (HBAD) by a cobaltochelatase that is constituted by 3 subunits, CobN, CobS and CobT, with molecular mass

Diet-induced changes in brain structure and behavior in old gerbils.

Aging is associated with many physiological alterations such as changes in metabolism, food intake and brain dysfunction. Possible ways to correct age-related brain dysfunction using dietary treatments still remains undeveloped. The aim of our research was to investigate whether long-term dietary treatment with 2-oxoglutarate (2-OX), which is involved in many regulatory pathways, together with pan

Narrow-Front Loop Migration in a Population of the Common Cuckoo Cuculus canorus, as Revealed by Satellite Telemetry.

Narrow migration corridors known in diurnal, social migrants such as raptors, storks and geese are thought to be caused by topographical leading line effects in combination with learning detailed routes across generations. Here, we document narrow-front migration in a nocturnal, solitary migrant, the common cuckoo Cuculus canorus, using satellite telemetry. We tracked the migration of adult cuckoo

The Language of Failure: Verbal Accounts in Financial Reports

The natural language that accompanies the accounting language in financial reports is not only a biased representation of the company, but also, we argue, a response to explicit as well as implicit external demands, expectations and accusations. Drawing on the notion of accounts, i.e. statements or responses that neutralizes critique caused by performance not meeting expectations, we analyze the n

Intensive multifactorial treatment modifies the effect of family history of diabetes on glycaemic control in people with Type 2 diabetes: a post hoc analysis of the ADDITION-Denmark randomized controlled trial

AimTo investigate whether intensive multifactorial treatment can reverse the predisposed adverse phenotype of people with Type 2 diabetes who have a family history of diabetes. MethodsData from the randomized controlled trial ADDITION-Denmark were used. A total of 1441 newly diagnosed patients with diabetes (598 with family history of diabetes) were randomized to intensive treatment or routine car

Inverse Problems for Quantum Graphs: Recent Developments and Perspectives

An introduction into the area of inverse problems for the Schrodinger operators on metric graphs is given. The case of metric finite trees is treated in detail with the focus on matching conditions. For graphs with loops we show that for almost all matching conditions the potential on the loop is not determined uniquely by the Titchmarsh-Weyl function. The class of all admissible potentials is cha

A validation of the first genome-wide association study of calcaneus ultrasound parameters in the European Male Ageing Study

Background: A number of single nucleotide polymorphisms (SNPs) have been associated with broadband ultrasound attenuation (BUA) and speed of sound (SOS) as measured by quantitative ultrasound (QUS) at the calcaneus in the Framingham 100K genome-wide association study (GWAS) but have not been validated in independent studies. The aim of this analysis was to determine if these SNPs are associated wi

Hydrolysis of Surfactants Containing Ester Bonds: Modulation of Reaction Kinetics and Important Aspects of Surfactant Self-Assembly

The effects of self-assembly on the hydrolysis kinetics of surfactants that contain ester bonds are discussed. A number of examples on how reaction rates and apparent reaction orders can be modulated by changes in the conditions, including an instance of apparent zero-order kinetics, are presented. Furthermore, it is shown that the examples on reaction kinetics display parallels and connections to

Jet energy measurement and its systematic uncertainty in proton-proton collisions at root s=7 TeV with the ATLAS detector

The jet energy scale (JES) and its systematic uncertainty are determined for jetsmeasured with the ATLAS detector using proton-proton collision data with a centre-of-mass energy of root s = 7 TeV corresponding to an integrated luminosity of 4.7 fb(-1). Jets are reconstructed from energy deposits forming topological clusters of calorimeter cells using the anti-kt algorithmwith distance parameters R

Municipal Landfilling Practice and Its Impact on the Water Resources - Jordan

Jordan is considered one of the most water-stressed countries in the world, with less than 150 cubic meters freshwater available per capita annually. Groundwater resources are clearly vital for Jordan´s population and economic wellbeing. It´s quality and amount has therefore to be managed in a sustainable way avoiding possible contaminations. Unfortunately the groundwater quality is threatened by

Grynig påskrislav, Stereocaulon incrustatum, i Sverige.

Grynig påskrislav Stereocaulon incrustatum är i Sverige rödlistad som Akut hotad och arten var inför denna inventering känd bara från en aktuell lokal i landet, i Blekinge. Där hittades arten första gången 1938 och växer numera i ett naturreservat med speciellt utformade skötselföreskrifter. Ytterligare åtta lokaler är kända från spridda landskap; Västergötland, Bohuslän, Öland, Dalarna och Jämtla

G protein-coupled receptor regulation: The role of protein interactions and receptor trafficking

The superfamily of G protein-coupled receptors (GPCR) is the largest gene family in the human genome. GPCR-mediated signaling operates in every human cell, and about 50% of existing clinically useful drugs act through GPCR. Kinins are proinflammatory peptides that are rapidly produced extracellularly following pathological insults and tissue damage. These peptides act through two GPCR subtypes, B1

Non-Model Based Finite-Horizon Sampled-Data Optimal Control Via Global Extremum Seeking

A non-model based approach to finite-horizon optimal sampled-data control of continuous-time nonlinear systems subject to input saturation constraints is proposed. The approach adapts the global optimisation method DIRECT to computing a periodically piecewise constant system input which minimises a possibly non-quadratic cost involving the system state and input. In the case where several similar

InAs/GaAs p-i-p quantum dots-in-a-well infrared photodetectors operating beyond 200 K

High-temperature operating performance of p-i-p quantum dots-in-awell infrared photodetectors (QDIPs) is successfully demonstrated. The optically active region consists of 10 layers of p-doped selfassembled InAs quantum dots (QDs) asymmetrically positioned in In0.15Ga0.85As quantum wells (QWs). The dark current is suppressed by an incorporated superlattice (SL) structure composed of 10 pairs of Al

Evaluation of Parameters of Bond Action between FRP and Concrete

This paper presents the evaluation of parameters describing bond action between fiber-reinforced polymer (FRP) and concrete in RC structures strengthened in flexure. The parameters were evaluated on the basis of fitting nonlinear finite-element results to experimental results from literature. Three-dimensional (3D) finite-element simulations were used to account for transversal effects without int