BACKGROUND: Studies of obesity with or without metabolic aberrations, commonly termed metabolically unhealthy or healthy obesity, in relation to cancer risk are scarce.METHODS: We investigated body mass index (BMI, normal weight/overweight/obesity) jointly and in interaction with metabolic health status in relation to obesity-related cancer risk (n = 23,630) among 797,193 European individuals. A m

Background: A comprehensive assessment of morbidity after allogeneic bone marrow transplantation (BMT) performed in childhood remains understudied. Methods: Seven hundred eighty-nine allogeneic BMT recipients who had survived ≥2 years after BMT performed between 1974 and 2014 at age

This article is part of the Dendritic Cell Guidelines article series, which provides a collection of state-of-the-art protocols for the preparation, phenotype analysis by flow cytometry, generation, fluorescence microscopy and functional characterization of mouse and human dendritic cells (DC) from lymphoid organs and various nonlymphoid tissues. DC are sentinels of the immune system present in al

An iterative algorithm is adopted to construct approximate representations of matrices describing the scattering properties of arbitrary objects. The method is based on the implicit evaluation of scattering responses from iteratively generated excitations. The method does not require explicit knowledge of any system matrices (e.g., stiffness or impedance matrices) and is well-suited for use with m

A survey of nuclear structure results obtained along α-decay chains stemming from isotopes of element 114, Fl, and element 115, Mc, is presented. Measures taken to ensure a reliable hand-over of nuclear spectroscopy output to nuclear structure theory are outlined. Possible links between decay chains starting from element 117, Ts, and element 115, Mc, are commented on. The experiments were conducte

Throughout history, people have used products from different microorganisms and plants for many medicinal and nutritional applications. Chilli peppers have been used for spicing up food, but also for their pharmacological properties. They contain alkaloid molecules called capsaicinoids, which have been shown to activate and desensitise the heat receptor - Transient Receptor Potential Vanilloid typ

The Tiber constituted a fundamental axis of transport and trade to Rome that made possible its subsistence and development in antiquity. However, different trajectories of research in the upper/middle and lower Tiber valley have led to an apparent perception of both stretches playing different roles in the supply of Rome, a perception not supported by wider archaeological evidence.This chapter exp

This essay investigates ecological epiphany in short stories by Zadie Smith and Joyce Carol Oates, moments in which characters confront the link between their own consumption habits and planetary damage. These moments build on a longer literary history of epiphany in modern fiction, a history that foregrounds suddenness, physicality, and the mundane, but these short stories also adapt epiphany to