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Assessment of Late Mortality Risk after Allogeneic Blood or Marrow Transplantation Performed in Childhood

Importance: Allogeneic blood or marrow transplantation (BMT) is a curative option for malignant and nonmalignant diseases of childhood. However, little is known about trends in cause-specific late mortality in this population during the past 3 decades. Objectives: To examine cause-specific late mortality among individuals who have lived 2 years or more after allogeneic BMT performed in childhood a

Full-time exposure to occupational noise during pregnancy was associated with reduced birth weight in a nationwide cohort study of Swedish women

Noise is a common exposure in the occupational work environment. Earlier studies of occupational noise and pregnancy outcome are few and show mixed results. To investigate if objectively assessed exposure to occupational noise during pregnancy is associated with reduced intrauterine growth and/or preterm birth a nationwide cohort study of 857,010 single births was initiated. Individual information

Towel reuse in hotels : Importance of normative appeal designs

Laundry is a major factor in hotel fresh water use. Pro-environmental appeals to encourage tourists to reuse towels and bed linen have received much attention in the literature, though findings have remained inconclusive. This paper presents the results of a large field experiment with 21,000 observations in seven hotels catering to the sun, sand & sea leisure tourism market in Gran Canaria, S

An experimental/numerical investigation of the role of the quarl in enhancing the blowout limits of swirl-stabilized turbulent non-premixed flames

The blowout limits of methane/air non-premixed swirl-stabilized flames were measured with and without quarl. The addition of a quarl significantly enhances the flame blowout limits. The transition from attached flame to blowout was mapped. To explore the role of the quarl, a series of OH-PLIF/PIV experiments, coupled with large eddy simulations (LES) using a transported probability density functio

Effect of reversible permeabilization in combination with different drying methods on the structure and sensorial quality of dried basil (Ocimum basilicum L.) leaves

The effect of reversible permeabilization as pre-treatment before air drying at 40 °C, vacuum drying and freeze drying was investigated. The parameters of the electric treatment provoked reversible permeabilization of the tissue causing the guard cells to open stomata (65 pulses of 650 V/cm, 150 μs pulse width, 760 μs between pulses). The drying times of each of the tested drying methods were adju

Measuring activities of daily living in Parkinson's disease : On a road to nowhere and back again?

Parkinson's disease (PD) is a progressive neurodegenerative disorder associated with increasing disability and limitations in performance of activities of daily living (ADL) despite availability of effective symptomatic therapy. Following an overview of classical test theory (CTT) and Rasch measurement theory (RMT), the case of a clinical PD trial aiming to demonstrate ADL improvements by using th

Heat flux reconstruction by inversion of experimental infrared temperature measurements – Application to the impact of a droplet in the film boiling regime

An Inverse Heat Conduction Problem (IHCP) is considered in order to estimate the transient heat flux extracted from a hot solid surface by an impinging droplet. The resolution of the IHCP is made with the so-called quadrupole method, which provides an analytical expression of the temperature and the heat flux at the front surface of the solid wall, where the drop impact takes place. In the experim

Evaluating the applicability of the radial approximation for pile heat exchangers

This paper appraises the efficacy of using an analytical radial approximation for different thermal pile heat exchanger geometries. Unsteady radial heat-flow from fluid in a pipe set within a grouted borehole into the external ground is well-documented and can be solved analytically very rapidly using Laplace Transforms (Javed and Claesson 2011). By comparing the radial model with finite-element s

Can high-pressure homogenization cause thermal degradation to nutrients?

Although originally developed for fat globule disruption in dairy applications, high-pressure homogenizers are extensively used in other food processing applications. Two newer applications are in forming nanoemulsion for delivering supplemented nutrients and as a preservation technique, both using higher pressures than traditional applications. This has raised concern that friction heat created i

Thin reaction zones in highly turbulent medium

A big database (23 cases characterized by Damköhler number less than unity) created recently in 3D Direct Numerical Simulation (DNS) of propagation of a statistically one-dimensional and planar, dynamically passive reaction wave in statistically stationary, homogeneous, isotropic turbulence is analyzed. On the one hand, the DNS data well support the classical Damköhler expression, i.e., square-roo

Effects of rainfall intensity and slope on interception and precipitation partitioning by forest litter layer

Rainfall interception and other hydrologic processes affected by the forest litter layer are usually related to litter characteristics and rainfall conditions, with limited studies that consider the influence of slope. To simulate the hydrological functions of the litter layer at different slope gradients, artificial rainfall experiments were conducted at four rainfall intensities (from 30 to 120

Creating sound immission mimicking real-life characteristics from a single wind turbine

This paper describes a method to synthesise wind turbine sounds to be used in sleep studies using a parameter-based synthesis. The parameter values were determined using recordings of several types of operating wind turbines, thorough investigations of the recorded sounds, previous reports on wind turbine sound characteristics, and acoustic knowledge on how sound properties change from source to a

An ecoimmunological approach to study evolutionary and ancient links between coagulation, complement and Innate immunity

Coagulation, complement, and innate immunity are tightly interwoven and form an alliance that can be traced back to early eukaryotic evolution. Here we employed an ecoimmunological approach using Tissue Factor Pathway Inhibitor (TFPI)-1-derived peptides from the different classes of vertebrates (i.e. fish, reptile, bird, and mammals) and tested whether they can boost killing of various human bacte

Performance and emissions of diesel-biodiesel-ethanol blends in a light duty compression ignition engine

An approach to reduce CO2 emissions while simultaneously keeping the soot emissions down from compression ignition (CI) engines is to blend in short chained oxygenates into the fuel. In this work, two oxygenated fuel blends consisting of diesel, biodiesel and EtOH in the ratio of 68:17:15 and 58:14:30 has been utilized and studied in a single cylinder light duty (LD) CI engine in terms of efficien

Investigation of OH and CH2O distributions at ultra-high repetition rates by planar laser induced fluorescence imaging in highly turbulent jet flames

For better understanding of the transient behavior of the flow/flame interaction in highly turbulent premixed flames, measurement techniques with sufficient temporal resolution are required. Using a burst-mode laser pumped optical parametric oscillator system, the present work demonstrated an ultra-high-speed diagnostic, for the first time, capable of visualizing hydroxyl radicals (OH) and formald

Physical and dosimetric properties of NaCl pellets made in-house for the use in prospective optically stimulated luminescence dosimetry applications

In this paper, NaCl pellets are produced in-house from ordinary household salt using simple and accessible methods, for the purpose of suggesting a cost-effective and available tool for various optically stimulated luminescence dosimetry applications. First, the pellets are investigated in terms of optimal configuration by varying combinations of grain sizes and compression forces. Then, the pelle

More Prevalent Prescription of Medicine for Hypertension and Metabolic Syndrome in Males from Couples Undergoing Intracytoplasmic Sperm Injection

Register-based studies have indicated that men with impaired fertility are at higher risk for developing various adult-onset diseases than fertile men. The majority of men undergoing ICSI treatment are sub-fertile and since they are in contact with the health care system, these men are well suited as target for preventive measures. Our study included all men (N = 459 766) who had fathered children

Cerebrospinal fluid concentrations of inflammatory markers in Parkinson’s disease and atypical parkinsonian disorders

Inflammation has been implicated in the pathogenesis of Parkinson’s disease (PD). We here investigate levels of inflammatory biomarkers in cerebrospinal fluid (CSF) in PD and atypical parkinsonian disorders (APD) compared with neurologically healthy controls. We included 131 patients with PD and 27 PD with dementia (PDD), 24 with multiple system atrophy (MSA), 14 with progressive supranuclear pals

Alpha 2-macroglobulin 5 bp insertion/deletion polymorphism increases the risk of recurrent venous thromboembolism

Alpha 2-macroglobulin (A2M) is a protease inhibitor that has been reported to neutralize thrombin, which may decrease the risk of thrombosis. A 5-base pairs (bp) insertion/deletion polymorphism (rs3832852) at the splice acceptor site of exon 18 has been shown to affect the binding of A2M with proteases. However, the role of this important variant in A2M in recurrent VTE is unknown. We investigated

A generalized flamelet tabulation method for partially premixed combustion

A flamelet tabulation method for partially premixed flames is proposed, in which partially premixed flamelets are incorporated as the archetypal flamelet elements. This method considers triple flame structures with both the partial premixing of fuel in the oxidizer side and the partial premixing of oxidizer in the fuel side, by replacing the pure-air and pure-fuel in the counterflow diffusion flam