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Dipolar Order in Molecular Fluids: II. Molecular Influence

The influence on the short-range packing in dipolar fluids by molecular shape and by additional higher order electrostatic moments has been investigated by molecular dynamic simulations. The dipole polarization was found to decrease as the particles were elongated parallel to the dipole and to increase for elongation perpendicular to the dipole, eventually forming a nematic order. The addition of

Toll-Like Receptor 3 Signalling Up-Regulates Expression of the HIV Co-Receptor G-Protein Coupled Receptor 15 on Human CD4(+) T Cells.

Many HIV-2 and SIV isolates, as well as some HIV-1 strains, can use the orphan 7-transmembrane receptor GPR15 as co-receptor for efficient entry into host cells. GPR15 is expressed on central memory and effector memory CD4(+) T cells in healthy individuals and a subset of these cells is susceptible to HIV-1 and SIV infection. However, it has not been determined whether GPR15 expression is altered

Thermoelectric performance of classical topological insulator nanowires

There is currently substantial effort being invested into creating efficient thermoelectric (TE) nanowires based on topological insulator (TI) chalcogenide-type materials. A key premise of these efforts is the assumption that the generally good TE properties that these materials exhibit in bulk form will translate into similarly good or even better TE performance of the same materials in nanowire

Soil disturbance favours threatened beetle species in sandy grasslands

Soil disturbance is recognised as an important restoration measure for conserving biodiversity in sandy soils. We used a soil disturbance (ploughing) experiment in a sandy grassland as well as a semi-natural disturbance (slope erosion enhanced by cattle trampling) gradient on a sandy slope to test the soil disturbance effects on the ground-living beetle community. Both experimental disturbance and

Bacteria in the Adventitia of Cardiovascular Disease Patients with and without Rheumatoid Arthritis.

The incidence of atherosclerosis is significantly increased in rheumatoid arthritis (RA). Infection is one factor that may be involved in the pathogenesis of both diseases. The cause of RA and atherosclerosis is unknown, and infection is one of the factors that may be involved in the pathogenesis of both diseases. The aims of this study were to identify bacteria in the aortic adventitia of patient

Risk aversion relates to cognitive ability: Preferences or Noise?

Recent experimental studies suggest that risk aversion is negatively related to cognitive ability. In this paper we report evidence that this relation may be spurious. We recruit a large subject pool drawn from the general Danish population for our experiment. By presenting subjects with choice tasks that vary the bias induced by random choices, we are able to generate both negative and positive c

Socioeconomic status and fertility before, during, and after the demographic transition: An introduction

BACKGROUND Despite a long interest in the historical fertility transition, there is still a lack of knowledge about disaggregated patterns that could help us understand the mechanisms behind the transition. In previous research the widely held view is that there was a change in the association between social status and fertility in conjunction with the fertility transition, implying that fertility

The PreAmplifier ShAper for the ALICE TPC detector

In this paper the PreAmplifier ShAper (PASA) for the Time Projection Chamber (TPC) of the ALICE experiment at LHC is presented. The ALICE TPC PASA is an ASIC that integrates 16 identical channels, each consisting of Charge Sensitive Amplifiers (CSA) followed by a Pole-Zero network, self-adaptive bias network, two second-order bridged-T filters, two non-inverting level shifters and a start-up circu

Nascent entrepreneurship and inventive activity: a somewhat new perspective

This paper focuses on the nexus between nascent entrepreneurship (NE) and inventive activity. It questions how NE affects inventive activity (including innovation and patenting) while analyzing the views and predictions that have used patenting as an indicator of entrepreneurial behavior. Using data on German researchers and controlling for their personal, professional and institutional attributes

Ontogenesis, semiosis and the epigenetic dynamics of biocultural niche construction

In this article I address the significance of semiotic processes supporting early social interaction, communication and learning in the evolution of the modern human niche of infancy and childhood, known to be extended even in comparison with closely related hominin species. Human infancy and childhood is a biocultural niche, embedded within and causally contributing to the expansion and elaborati

Nordic City Regions in the Creative Class Debate: Putting the Creative Class Thesis to a Test

The Nordic countries have a quite different urban structure and social systems than the USA. Denmark, Finland, Norway and Sweden may then constitute a critical test of the empirical reach of Richard Florida's much cited creative class thesis beyond its empirical basis in the USA. This paper employs comparative statistics to examine the importance of the quality of place in attracting members of th

The Learning Curve for Laparoscopic Radical Prostatectomy: An International Multicenter Study

Purpose: It is not yet possible to estimate the number of cases required for a beginner to become expert in laparoscopic radical prostatectomy. We estimated the learning curve of laparoscopic radical prostatectomy for positive surgical margins compared to a published learning curve for open radical prostatectomy. Materials and Methods: We reviewed records from 8,544 consecutive patients with prost

Melatonin receptors in pancreatic islets - Linking a genetic variant to functional phenotype

Popular Abstract in Swedish Diabetes är en folksjukdom som kännetecknas av förhöjt blodsocker. Sjukdomens förekomst ökar dramatiskt över hela världen och beskrivs ofta som en pandemi. I huvudsak finns det två olika former av diabetes, typ 1 och typ 2. Typ 1 drabbar oftast barn och ungdomar – de insulinproducerande β-cellerna förstörs av kroppens egna immunförsvar. Vid typ 2 diabetes ser sjukdomsbiDefective insulin secretion and insulin resistance are the two hallmarks of Type 2 Diabetes (T2D). The pathophysiology of the disease is not fully understood but genetic susceptibility for the disease is a new major player in the understanding of the underlying mechanisms. T2D research has in recent years invested tremendous efforts in identifying new risk variants for the disease. It has proven t

Alpha B-crystallin - a validated prognostic factor for poor prognosis in squamous cell carcinoma of the oral cavityl

Conclusion: Alpha B-crystallin was found to be an independent prognostic marker for poor prognosis in oral cavity tumours. For oropharyngeal cancer, alpha B-crystallin had no prognostic value. Objective: The aim of this study was to see if earlier findings of alpha B-crystallin as an independent prognostic marker, and SPARC/osteonectin, PAI-1 and uPA as a prognostic combination for poor outcome in

A case study on software risk analysis and planning in medical device development

Software failures in medical devices can lead to catastrophic situations. Therefore, it is crucial to handle software-related risks when developing medical devices, and there is a need for further analysis of how this type of risk management should be conducted. The objective of this paper is to collect and summarise experiences from conducting risk management with an organisation developing medic

Bone Mineral Density in Haemophilila: A Treatment Outcome

Background: Osteoporosis is increasingly recognised as one of the major public health problems throughout the world and has massive socioeconomic implications. It has previously been shown that patients with severe haemophilia and not receiving any prophylactic treatment render a high risk of reduced bone density. Aims: To evaluate Bone Mineral Density (BMD) in patients with haemophilia of differ