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Circulating heat shock protein and heat shock protein antibody levels in established hypertension.

OBJECTIVE Serum Hsp60 and anti-Hsp65 antibody levels are raised in subjects with borderline hypertension, and there is an association between circulating Hsp60 levels and early atherosclerosis. Given the recognized relationship between hypertension and atherosclerosis, this study determined heat shock protein and heat shock protein antibody levels in subjects with established hypertension.METHODS

Prediction of permanent deformations in asphalt concrete using the mechanistic-empirical pavement design guide

Permanent deformations, or rutting, are internationally considered to be one of the most serious distress mechanisms in asphalt pavements. Deterioration modeling is an important tool for performance prediction and diagnostics of pavements. The Mechanistic-Empirical Pavement Design Guide (M-E PDG) model used for calculation of permanent deformation in asphalt layers was to be evaluated. It was acco

In-plane tension behaviour of masonry

The main purpose of the present work is to increase knowledge of in-plane tension behav-iour of masonry and develop a model able to describe the impact of parameters influencing cracking caused by restrained shrinkage. In the process the mechanism of load transfer between units and mortar joints is described. The influence of cohesion between units and mortar joints, unit and joint geometry and ex

Attitude towards remission induction for elderly patients with acute myeloid leukemia influences survival.

Combination chemotherapy may induce remission from acute myeloid leukemia (AML), but validated criteria for treatment of elderly are lacking. The remission intention ( RI) rate for elderly patients, as reported to the Swedish Leukemia Registry, was known to be different when comparing the six health care regions, but the consequences of different management are unknown. The Leukemia Registry, cont

Distribution and function of TRP ion channels in primary sensory neurons

Popular Abstract in Swedish Vad hade vi varit utan våra sinnen? Föreställ dig en värld utan att kunna se, höra, lukta, smaka och känna. Det är med hjälp av våra sinnen som kroppen kan känna vad som händer i vår omgivning. Ett av våra sinnen är smärtsinnet, som har till uppgift att varna oss för inre och yttre faror. Trots att smärta är den i särklass vanligaste orsaken till mänskligt lidande, så äIt is frequently argued that cannabinoids exert part of their analgesic and anti-inflammatory effects via activation of the cannabinoid CB1 receptor located on TRPV1-expressing primary sensory nerve fibres in peripheral tissues. However, we find no evidence of CB1 receptor immunoreactivity on nerve fibres in rat or mouse hindpaw skin and mesenteric artery. The CB1 receptor agonists anandamide and

Recent changes in the marine environment in relation to climate, hydrography, and human impact –with special reference to fjords on the Swedish west coast

To obtain a perspective of changes occurring in the marine environment it is essential to study an area over a long time span. Doing so might also facilitate the understanding of the mechanisms and processes that govern a certain marine setting. In this thesis, changes in the pelagic and benthic environment during the last c. 200 years have been investigated in two fjords on the Swedish west coast

Slepian models and regression approximations in crossing and extreme value theory

In crossing theory for stochastic processes the distribution of quantities such as distances between level crossings, maximum height of an excursion between level crossings, amplitude and wavelength, etc., can only be written in the form of infinite-dimensional integrals, which are difficult to evaluate numerically. A Slepian model is an explicit random function representation of the process after

Formation of phosphatidylethanol in vitro in red blood cells from healthy volunteers and chronic alcoholics.

Phosphatidylethanol (PEth) is an abnormal phospholipid, formed only in the presence of ethanol via a transphosphatidylation reaction of phospholipase D (PLD). PEth in blood is a promising new marker of alcohol abuse. Blood PEth is found almost exclusively in red cells. This study was performed to investigate a possible PEth formation in human red cells from alcoholics and healthy individuals, at p

Polynomial time approximation schemes for max-bisection on planar and geometric graphs

The max-bisection and min-bisection problems are to find a partition of the vertices of a graph into two equal size subsets that, respectively, maximizes or minimizes the number of edges with endpoints in both subsets. We design the first polynomial time approximation scheme for the max-bisection problem on arbitrary planar graphs solving a long-standing open problem. The method of solution involv

A prospective study of adiposity and all-cause mortality: the Malmö Diet and Cancer Study.

OBJECTIVE: This study aims to examine the association between various measures of adiposity and all-cause mortality in Swedish middle-aged and older men and women and, additionally, to describe the influences of age and sex on these associations. RESEARCH METHODS AND PROCEDURES: A prospective analysis was performed in a cohort of 10,902 men and 16,814 women ages 45 to 73 years who participated in

Migration Along Orthodromic Sun Compass Routes by Arctic Birds

Flight directions of birds migrating at high geographic and magnetic latitudes can be used to test bird orientation by celestial or geomagnetic compass systems under polar conditions. Migration patterns of arctic shorebirds, revealed by tracking radar studies during an icebreaker expedition along the Northwest Passage in 1999, support predicted sun compass trajectories but cannot be reconciled wit

Effect of flow reversal on the shear induced formation of multilamellar vesicles

The influence of rate controlled flow reversal on the transition from planar lamellae to multilamellar vesicles (MLV) using a nonionic lamellar phase consisting of 40 wt % triethylene glycol monodecyl ether (C10E3 in D2O) is investigated by means of time-resolved rheo-small-angle light and neutron scattering (SALS, SANS). Flow reversal provides the possibility to control the kinetics of the transi

Brandförlopp och brandspridning i stora lokaler : en vägledning förval av beräkningsmodeller : översikt utförd på uppdrag av BRANDFORSK

Området industribränder kan som det redovisats i denna rapport sammanfattas i bl.a. följande punkter: Det existerar ett antal principiellt skilda beräkningsmetoder och dessa inkluderar okomplicerade beräkningsuttryck, zon-modeller och fältmodeller. Val av metod maste bero på ändamalet med beräkningen, någon universalmetod eller universaldatorprogram existerar inte och kan inte ens skönjas. En val

Dissecting karyotypic patterns in colorectal tumors: two distinct but overlapping pathways in the adenoma-carcinoma transition.

More than 500 colorectal tumors with clonal chromosomal abnormalities have been reported. Although the pattern of aberrations is nonrandom, no specific primary or secondary karyotypic abnormality has been identified. Also, the chronological order in which the aberrations appear during disease progression is not well known. One reason why our understanding of the cytogenetic evolution is unclear is

Use of morphology to characterize and manage common adnexal masses.

The use of grey-scale ultrasound morphology to characterize a pelvic mass may also be called ‘pattern recognition’. The grey-scale ultrasound image provides us with the same information as that obtained by the surgeon or pathologist when he or she cuts a surgical specimen to see what it looks like inside. Many pelvic masses have such a typical macroscopic appearance that a fairly confident diagnos

Changes of cartilage and bone markers after intraarticular glucocorticoid treatment with and without postinjection rest in patients with rheumatoid arthritis

Background: Joint immobilisation improves the therapeutic effect of intra-articular glucocorticoid injection for knee synovitis. This may be due to retarded steroid resorption by immobilisation, a procedure that also could influence cartilage and bone metabolism. Objective: To evaluate changes in cartilage and bone turnover after intra-articular glucocorticoid treatment for knee synovitis with and

Cell chromatography: Separation of different microbial cells using IMAC supermacroporous monolithic columns

Supermacroporous monolithic columns with CU2+-IDA ligands have been successfully used for chromatographic separation of different types of microbial cells. The bed of monolithic matrix is formed by a cryogel of poly(acrylamide) cross-linked with methylenebis(acrylamide) and has a network of large (10- 100 mu m) interconnected pores allowing unhindered passage of whole cells through the plain cryog

Rotational and Single-particle Structures in 83Zr

The band structure of Zr-83 has been investigated using the Daresbury recoil separator and TESSA array with 20 Compton suppressed Ge detectors and the reaction Si-28 (Ni-58, 2pn) at 195 MeV. DCO ratios have been used to make many new spin assignments. The three known rotational bands have been extended up to the onset of the five quasiparticle bands. On the basis of the 21/2+, 23/2+ and 25/2+ yras