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Computational Tools for Antenna Analysis and Design

Many engineers and scientists prevalently use computational tools in electromagnetics, which is also the predominant case for antennas. The ever-increasing number of applications and technologies that employ antennas create a constant demand to improve and extend existing tools and develop new ones. This dissertation investigates computational tools for antenna analysis and design. Antenna current

Human Leucocyte Antigen, Infections and Systemic Inflammatory Biomarkers in Early Atherosclerosis in Children and Adolescents with Type 1 Diabetes

Background: This prospective study focuses on factors associated with arterial damage in children with type 1 diabetes (T1D). Materials and Methods: Eighty children and adolescents with T1D (mean age 15, range: 8-20 yrs; mean diabetes duration 7, range: 0.5 to 19 years) were investigated twice, approximately 2 years apart, for carotid artery intima-media thickness (cIMT) and compliance (CAC), flow

Self-Assembly in Lipid-Protein Systems : Lung Surfactant, Stratum Corneum and Model Membranes

Den yttersta barriären mellan luften och blodomloppet i våra lungor består av en lipid-protein film. Denna lipid-protein blandning kallas för lungsurfaktant. Filmen bestående av lungsurfaktant stabiliserar alveolerna i våra lungor och gör att vi kan andas utan motstånd. Brist av lungsurfaktant kan orsaka svåra sjukdomar, till exempel hos förtidigt födda barn som ännu inte hunnit bilda tillräckligtThis thesis explores lipid self-assembly and aims to give a broad picture of self-assembly structures in simple and complex lipid-protein systems. The systems studied are lung surfactant, stratum corneum and simple model membranes. The lung surfactant mixture lines the alveolus in our lungs and stabilises the air- tissue interface. The lung surfactant lipid phase behaviour was here investigated wi

Absolute lung size and the sex difference in breathlessness in the general population

Background Breathlessness is associated with major adverse health outcomes and is twice as common in women as men in the general population. We evaluated whether this is related to their lower absolute lung volumes. Methods Cross-sectional analysis of the population-based Swedish CardioPulmonarybioImage Study (SCAPIS) Pilot, including static spirometry and diffusing capacity (n = 1,013; 49% women)

Maggot secretions suppress pro-inflammatory responses of human monocytes through elevation of cyclic AMP

Aims/hypothesis: Maggots of the blowfly Lucilia sericata are used for the treatment of chronic wounds. As monocytes may contribute to the excessive inflammatory responses in such wounds, this study focussed on the effects of maggot secretions on the pro-inflammatory activities of these cells. Methods: Freshly isolated monocytes were incubated with a range of secretions for 1 h and then stimulated

From Epipalaeolithic petroglyphs to Roman graffiti : Stylistic variability of anthropomorphs at Gebel el Silsila (Upper Egypt)

Gebel el-Silsila displays an astounding concentration of incised illustrations, of which anthropomorphic figures are frequent motifs. These figures were produced over several millennia; from prehistoric petroglyphs to pictorial graffiti of dynastic periods and throughout into Roman days. Spanning over six millennia visitors to Gebel el Silsila depicted huntsmen, warriors, boatmen, and horsemen, reGebel el Silsila displays an astounding concentration of incised illustrations, of which anthropomorphic figures are frequent motifs. These figures were produced over several millennia: from prehistoric petroglyphs to pictorial graffiti of dynastic periods and throughout into Roman days. Spanning over six millennia visitors to Gebel el Silsila depicted huntsmen, warriors, boatmen, and horsemen, re

Opening the door to social equity : local and participatory approaches to transportation planning in Montreal

Purpose: Transportation systems play a key role in providing individuals with a diversity of means to access their desired destinations and have significant impacts on their quality of life. The social perspective of mobility is, however, marginalized in the current model of transportation planning and significant changes are called for. This study aims to identify the barriers and opportunities o

A pragmatic, phase III, multisite, double-blind, placebo-controlled, parallel-Arm, dose increment randomised trial of regular, low-dose extended-release morphine for chronic breathlessness : Breathlessness, Exertion and Morphine Sulfate (BEAMS) study protocol

Introduction Chronic breathlessness is highly prevalent and distressing to patients and families. No medication is registered for its symptomatic reduction. The strongest evidence is for regular, low-dose, extended-release (ER) oral morphine. A recent large phase III study suggests the subgroup most likely to benefit have chronic obstructive pulmonary disease (COPD) and modified Medical Research C

The glucagon-like peptide 1 receptor agonist Exendin-4 decreases relapse-like drinking in socially housed mice

Glucagon-like peptide-1 (GLP-1) is a gut peptide that regulates food intake and glucose metabolism. GLP-1 is also produced and released in the brain, and GLP-1 receptors are expressed in brain regions important for alcohol and drug reward, and for the development of addiction. GLP-1 receptor agonists can decrease alcohol intake acutely in rodents. However, alcohol use disorder is a chronic conditi

Dynamic charging solutions in Sweden : An overview

Dynamic Charging, meaning supplying electric energy to electric vehicles while moving and also referred to as Electric Road Systems (ERS), can be implemented in a number of different ways. In Sweden, no less than four different technologies are being developed and/or demonstrated. This is, in an international comparison, unique. This paper represents an effort to describe these different technolog

Combinations of maggot excretions/secretions and antibiotics are effective against Staphylococcus aureus biofilms and the bacteria derived therefrom

Objectives: Maggots of the blowfly Lucilia sericata are used for the treatment of chronic wounds. Previously we reported that maggot excretions/secretions (ES) break down Staphylococcus aureus biofilms but do not kill the bacteria. As many antibiotics are not effective against biofilms we assessed the effect of combinations of ES and antibiotics on S. aureus biofilms and on the survival of the bac

Lactoferrin Glu561Asp polymorphism is associated with susceptibility to herpes simplex keratitis

Lactoferrin plays an important role in the defense against infections, including herpes simplex virus (HSV) keratitis. We studied the impact of three single nucleotide polymorphisms in the human lactoferrin gene on the susceptibility to HSV infections of the eye and the severity of such infections. Lactoferrin gene polymorphisms were determined by PCR combined with restriction fragment length anal

Furin is a chemokine-modifying enzyme : In vitro and in vivo processing of CXCL10 generates a C-terminally truncated chemokine retaining full activity

Chemokines comprise a class of structurally related proteins that are involved in many aspects of leukocyte migration under basal and inflammatory conditions. In addition to the large number of genes, limited processing of these proteins by a variety of enzymes enhances the complexity of the total spectrum of chemokine variants. We have recently shown that the native chemokine CXCL10 is processed

Monomethylfumarate affects polarization of monocyte-derived dendritic cells resulting in down-regulated Th1 lymphocyte responses

Psoriasis vulgaris, a type-1 cytokine-mediated chronic skin disease, can be treated successfully with fumaric acid esters (FAE). Beneficial effects of this medication coincided with decreased production of IFN-γ. Since dendritic cells (DC) regulate the differentiation of T helper (Th) cells, this study focussed on effects of monomethylfumarate (MMF, bioactive metabolite of FAE) on polarization of

Narratives of biorefinery innovation for the bioeconomy – Conflict, consensus, or confusion?

Transition narratives are stories promoting particular pathways for development, promoting specific actions, strategies, and interventions to enable certain outcomes in socio-technical transitions. Narratives centered around biorefineries take a significant role in the growing bioeconomy discourse, yet they express remarkably different visions for the transition. The paper uses Q methodology to id

MERLIN : A French-German space lidar mission dedicated to atmospheric methane

The MEthane Remote sensing Lidar missioN (MERLIN) aims at demonstrating the spaceborne active measurement of atmospheric methane, a potent greenhouse gas, based on an Integrated Path Differential Absorption (IPDA) nadir-viewing LIght Detecting and Ranging (Lidar) instrument. MERLIN is a joint French and German space mission, with a launch currently scheduled for the timeframe 2021/22. The German S