Controlling DNA compaction and the interaction with model biomembranes
The studies described in this thesis forms part of a larger collaborative project, Neonuclei, with the objective to design a module for packaging the negatively charged DNA into a ”neonucleus” with transcription competence. There are many applications that require control of DNA compaction, i.e. packaging or condensation. One example is the systemic delivery of DNA for gene therapy. In this work,