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Predictors and survival of synchronous peritoneal carcinomatosis of colorectal origin : a population-based study

The aim of our study was to provide population-based data on incidence and prognosis of synchronous peritoneal carcinomatosis and to evaluate predictors for its development. Diagnosed in 1995-2008, 18,738 cases of primary colorectal cancer were included. Predictors of peritoneal carcinomatosis were analysed by multivariable logistic regression analysis. Median survival in months was calculated by

A clinicopathologic analysis of peritoneal metastases of colorectal and appendiceal origin

OBJECTIVE: To predict clinical outcome by classification of peritoneal metastases (PM) of colorectal or appendiceal origin.BACKGROUND: This study investigates whether standardized histological classification can predict outcome for PM of colorectal or appendiceal origin treated with cytoreduction and hyperthermic intraperitoneal chemotherapy (HIPEC).METHODS: Histology of PM (n = 269) was evaluated

A trial of consent procedures for future research with clinically derived biological samples

BACKGROUND: The aims of this study were to determine which consent procedure patients prefer for use of stored tissue for research purposes and what the effects of consent procedures on actual consenting behaviour are.METHODS: We offered 264 cancer patients three different consent procedures: 'one-time general consent' (asked written informed consent), 'opt-out plus' (had the opportunity to opt ou

Valuation of nature-based tourism using contingent valuation survey : evidence from South Africa

The increasing pressure within developing countries to focus on other national objectives has led to declining fiscal transfers for conservation. This paper assesses the potential for a typical large African park such as the Kruger National Park to generate additional revenue through an entrance fee hike in order to finance park operations. This is investigated by estimating international tourists

Recreation demand and pricing policy for international tourists in developing countries : evidence from South Africa

National park agencies in Africa often lack incentives to maximize revenue, despite the decline in conservation subsidies from the State. We explore the potential of pricing policy to generate funds for extensive conservation. We estimate recreation demand by international tourists for a popular South African park, calculate the consumer surplus and find the revenue-maximizing entrance fee. Our re

Charting a “Green Path” for Recovery from COVID-19

Should the economic recovery from the 2019 novel coronavirus disease (COVID-19) be green? The current crisis is so severe that we should not take the answer for granted. It requires serious thought and we start by reviewing some arguments for and against a green approach. A crucial element is of course to see how different industries fare in the current crisis. Our empirical contribution is to exa

Evaluating The Prospects Of Benefit Sharing Schemes In Protecting Mountain Gorillas In Central Africa

Presently, the mountain gorilla in Rwanda, Uganda, and the Democratic Republic of Congo is endangered mainly by poaching and habitat loss. This paper sets out to investigate the possible resolution of poaching involving the local community by using benefit sharing schemes with local communities. Using a bioeconomic model, the paper demonstrates that the current revenue sharing scheme yields subopt

Treatment outcome with pencillin G or cloxacillin in penicillin susceptible Staphylococcus aureus bactearemi

An increasing proportion of penicillin-susceptible Staphylococcus aureus (PSSA) has been reported over the last years. The aim of this retrospective study was to compare penicillin G with cloxacillin in the treatment of PSSA bloodstream infections. The primary outcome was the mortality rate after 90 days and the secondary outcome was the development of treatment complications of varying severity.

Phase-matched extreme-ultraviolet frequency-comb generation

Extreme ultraviolet (XUV) laser radiation is commonly produced via high-harmonic generation (HHG) in gases. The lasers that drive this process typically operate at low pulse repetition rates (10 MHz) necessary. Unfortunately, at high repetition rates, plasma accumulates in the XUV generation region and prevents phase-matching, resulting in low HHG efficiency. We use high-temperature gas mixtures t

Vertical test results on ESS medium and high beta elliptical cavity prototypes equipped with helium tank

The ESS elliptical superconducting Linac consists of two types of 704.42 MHz cavities, medium and high beta, to accelerate the beam from 216 MeV (spoke cavity Linac) up to the final energy at 2 GeV. The last Linac optimization, called Optimus+[1], has been carried out taking into account the limitations of SRF cavity performance (field emission). The medium and high-beta parts of the Linac are com

Phobos base : Concept of operations and architecture for a permanent human presence on the Martian moon Phobos

This paper is based on the work done for the 2017 AIAA Student Design Competition-Human Spaceflight: Phobos Base. One of humanity's major challenges when travelling to Mars is represented by the existence of an atmosphere around the red planet. In fact, even though the Martian atmospheric density is only about 1% of that of Earth, the entry, descent and landing (EDL) procedure for large payloads i

Climate Policy and Financial Markets

Climate change represents a serious, as-yet-unresolved global commons problem. After decades of international climate negotiations, 195 nations adopted the Paris climate agreement in December 2015. The subsequent election of Donald Trump as US president in 2016 was seen as a setback for climate policy. However, evaluating the impacts of both events is difficult because their results in terms of mi

Search for a heavy charged boson in events with a charged lepton and missing transverse momentum from pp collisions at s =13 TeV with the ATLAS detector

A search for a heavy charged-boson resonance decaying into a charged lepton (electron or muon) and a neutrino is reported. A data sample of 139 fb-1 of proton-proton collisions at s=13 TeV collected with the ATLAS detector at the LHC during 2015-2018 is used in the search. The observed transverse mass distribution computed from the lepton and missing transverse momenta is consistent with the distr

Sex differences in blood-based biomarkers in individuals with autosomal dominant Alzheimer's disease

BACKGROUND: Blood-based biomarkers are a promising tool for early detection of Alzheimer's disease (AD). We recently showed that individuals with autosomal-dominant AD due to the E280A mutation in the presenilin1 gene (PSEN1) showed elevated levels of plasma tau phosphorylated at threonine 217 (P-tau217) and neurofilament light chain (NfL), as early as approximately 20 years before clinical onset.

Search for long-lived neutral particles produced in pp collisions at s =13 TeV decaying into displaced hadronic jets in the ATLAS inner detector and muon spectrometer

A search is presented for pair production of long-lived neutral particles using 33 fb-1 of s=13 TeV proton-proton collision data, collected during 2016 by the ATLAS detector at the LHC. This search focuses on a topology in which one long-lived particle decays in the ATLAS inner detector and the other decays in the muon spectrometer. Special techniques are employed to reconstruct the displaced trac

Genetic influence during the early phases of Alzheimer's disease on longitudinal cognitive impairment

BACKGROUND: The rate of cognitive decline in the early stages of Alzheimer's disease (AD) is variable, which may be partly due to genetic factors. We therefore investigated genetic predictors of longitudinal cognitive decline in AD. METHOD: In the Swedish BioFINDER study, we used polygenic scores (PGS) (of AD, intelligence and educational attainment), and genetic variants (in a genome-wide associa

Measurement of the cross-section and charge asymmetry of W bosons produced in proton–proton collisions at √s=8TeV with the ATLAS detector

This paper presents measurements of the W+→ μ+ν and W-→ μ-ν cross-sections and the associated charge asymmetry as a function of the absolute pseudorapidity of the decay muon. The data were collected in proton–proton collisions at a centre-of-mass energy of 8 TeV with the ATLAS experiment at the LHC and correspond to a total integrated luminosity of 20.2fb-1. The precision of the cross-section meas

Scanning the solutions for the sustainable supply of forest ecosystem services in Europe

Forests are key components of European multifunctional landscapes and supply numerous forest ecosystem services (FES) fundamental to human well-being. The sustainable provision of FES has the potential to provide responses to major societal challenges, such as climate change, biodiversity loss, or rural development. To identify suitable strategies for the future sustenance of FES, we performed a s