Age-dependent associations between type 1 diabetes risk genes HLA, INS VNTR, and CTLA-4 and autoantibodies to GAD65 (GADAs), ICA512/IA-2, insulin, and islet cells were determined by logistic regression analysis in 971 incident patients with type 1 diabetes and 702 control subjects aged 0-34 years. GADAs were associated with HLA-DQ2 in young but not in older patients (P = 0.009). Autoantibodies to

The topic of this thesis is the study of finite volume methods for hyperbolic conservation laws on non-uniform meshes. A high-order hyperbolic reconstruction method is presented. The method is constructed for quadrilateral meshes, since more realistic hyperbolic problems involve more complicated problem domains than the standard rectangular ones. The method is an extension of the well known

The processing advantage for words in the right visual field (RVF) has often been assigned to parallel orthographic analysis by the left hemisphere and sequential by the right. The authors investigated this notion using the Reicher–Wheeler task to suppress influences of guesswork and an eye-tracker to ensure central fixation. RVF advantages obtained for all serial positions and identical U-shaped

Selected papers from the 2002 Conference in the Pepperdine University lecture hall facilities in Heidelberg.

Flint has a limited distribution in the Scandinavian area, natural sources being largely confined to the southern regions. Here, the use of flint for making daggers and polished axes during the Neolithic is widespread and extensive. There is also evidence for mining of flint at Södra Sallerup in southern Sweden and on several sites in Denmark, but flint is available in till deposits as well. The

In this paper an approximate expression for the first inverse moment sf(1 - lambda) Sigma(k=1)(t) lambda(t-k)phi(k)phi(k)(T) + lambda(t) (1 - lambda)P-0(i-1), where phi(k) is a Gaussian stationary vector process is derived. This generalized quadratic form is the estimate of the information matrix when using the Recursive Least Squares (RLS) algorithm with forgetting factor. This estimator is commo

Background. The aim of the present study was to establish the magnitude and time-course of C-reactive protein increases following routine neurosurgical procedures in the absence of clinical and laboratory signs of infection. Method. C-reactive protein levels were studied daily following ventriculo-peritoneal shunt implantation, anterior cervical fusion, vestibular schwannoma operation, supratentor

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This paper uses cumulative export experience functions to explore the structural dynamics of South Africa's exports for the period 1990-2003. It finds a large spread of emerging non-traditional accelerating export products across industry clusters of different factor intensifies, steadily increasing their proportion in total exports and her main markets. Shift-share and correlation analyses show t

Solid-phase microextraction (SPME) with a disposable ionic liquid (IL) coating was developed for headspace extraction of benzene, toluene, ethylbenzene, and xylenes (BTEX) in paints. The SPME fiber was coated with IL prior to every extraction, then the analytes were extracted and desorbed on the injection port of gas chromatography, and finally the IL coating on the fiber was washed out with solve

Context: Survivors of childhood- onset ( CO) acute lymphoblastic leukemia ( ALL) treated with prophylactic cranial radiotherapy often exhibit GH deficiency ( GHD), which is associated with increased prevalence of cardiovascular risk factors and cardiac dysfunction. Objective: The objective of the study was to evaluate the effect of GH replacement on cardiovascular risk factors and cardiac function

HSL from chicken adipose tissue exhibits remarkable activation upon phosphorylation with cAMP-dependent protein kinase (cAMP-PK) compared to HSL from rat and human adipose tissue. In order to characterize the chicken HSL enzyme, it was purified 3500 fold from a chicken adipose tissue homogenate using pH 5.2 precipitation and anion-exchange chromatography. The purified chicken HSL was identified as

Throughout the lifespan of an individual, enormous numbers of mature blood cells are generated by hematopoietic stem cells (HSCs) in the bone marrow (BM). The HSC is a cell that can self-renew to maintain the HSC pool and differentiate into all types of mature blood cells. HSCs can also be mobilized out of the BM into blood and can be isolated from different sources including mobilized blood, umbi

The availability of dual energy X-ray absorptiometry (DXA) varies markedly in different countries. There is, however, little information to indicate the optimal requirements for this technology. The principal aim of this study was to estimate the requirements for DXA in Europe for the assessment and treatment of osteoporosis. Three assessment scenarios were chosen. The first envisaged screening of