This study investigated the role of the antimicrobial peptide cathelicidin in Escherichia coli O157:H7 infection and subsequent renal damage. Mouse and human cathelicidin, CRAMP and LL-37, respectively, killed E. coli O157:H7 in vitro. Intestines from healthy wild-type (129/SvJ) and cathelicidin-knock-out (Camp(-/-)) mice were investigated, showing that cathelicidin-deficient mice had a thinner co

beta-Alanine synthase (PAS) is the third enzyme in the reductive pyrimidine catabolic pathway, which is responsible for the breakdown of the nucleotide bases uracil and thymine in higher organisms. It catalyzes the hydrolysis of N-carbamyl-beta-alanine and N-carbamyl-beta-aminoisobutyrate to the corresponding beta-amino acids. beta ASs are grouped into two phylogenetically unrelated subfamilies, a

The aim of the present study was to investigate whether virulent CagA positive Helicobacter pylori strains are those preferentially related to abdominal aortic aneurysm (AAA) rupture. Several microorganisms have been linked to aneurysm development. Chronic Chlamydophila pneumoniae infection has been suggested as a possible contributing factor for the development and expansion of AAA. Previous stud

Det mest spännande fyndet under SLF:s höstexkursion till Skäckerfjällen i Jämtland var utan tvekan västlig kolvlav Pilophorus strumaticus. Efter det mycket överraskande första fyndet lyckades vi hitta arten på ytterligare tre lokaler. Då handlar om en art som anses nationellt utdöd fann vi det värt att skriva en separat artikel om arten.

Background: The aim of the present study was to evaluate the prevalence and severity of lower limb lymphedema after pelvic lymphadenectomy and radiotherapy to the pelvic lymph nodes in patients with prostate cancer. Methods: Twenty-six patients underwent combined treatment for high-risk node-positive prostate cancer at Skane University Hospital between April 2008 and March 2011. The treatment cons

The overall objective of this study was to combine national forest inventory data and remotely sensed data to produce pan-European maps on growing stock and above-ground woody biomass for the two species groups " broadleaves" and " conifers" An automatic up-scaling approach making use of satellite remote sensing data and field measurement data was applied for EU-wide mapping of growing stock and a

Abstract in Spanish Este artículo, el primero en un proyecto de investigación recién iniciado sobre el uso de tabaco en la literatura latinoamericana, tiene dos partes. En la primera se discute el papel del cigarrillo en la producción cultural, y se afirma que el cigarrillo es algo como un significante vacío que tiene que llenarse con historias – desde ese sentido, un producto ideal para la public

Excited states in Ag-96 were populated in fragmentation of an 850-MeV/u Xe-124 beam on a 4-g/cm(2) Be target. Three new high-spin isomers were identified and the structure of the populated states was investigated. The level scheme of Ag-96 was established, and a spin parity of (13(-)), (15(+)), and (19(+)) was assigned to the new isomeric states. Shell-model calculations were performed in various

Longer periods of drought and droughts of higher intensity are expected to become increasingly frequent with future climate change. This has implications for the microbially mediated turnover of soil organic matter (SOM), which will feedback to the global C cycle. In this study, we addressed the microbial dynamics underlying the pulse of respiration following rewetting of dry soil, and how the dro

Aim and method: We analysed DNA samples isolated from individuals born with cleft lip and cleft palate to identify deletions and duplications of candidate gene loci using array comparative genomic hybridisation (array-CGH). Results: Of 83 syndromic cases analysed we identified one subject with a previously unknown 2.7 Mb deletion at 22q11.21 coinciding with the DiGeorge syndrome region. Eighteen o

Removing lignin from black liquor is one way of recovering valuable organic substances for alternative use as well as reducing the energy surplus in a modern, energy-optimised kraft pulp mill. By using the recently developed "LignoBoost" process it is possible to upgrade black liquor streams of different origin to form valuable chemicals. In this investigation a combination of membrane filtration

Consider the transmission of complex-valued symbols over N parallell channels in additive white Gaussian noise. It is well known that linear precoding of the complex-valued data improves system performance (e. g. symbol error rate, information rate, MMSE, etc.) at a cost of increased decoding complexity at the receiver. This work constructs precoders that are constrained to have a decoding complex

Metalworking fluid (MWF) aerosols are associated with respiratory disorders including asthma and hypersensitivity pneumonitis. The aims of this study were to describe exposure to inhalable MWF aerosols and volatile compounds in machine shops, to estimate the influence of important determinants of exposure and to compare different sampling techniques for MWF aerosols. Personal full-shift air sample

BACKGROUND: Restrictions in social and leisure activity can have negative consequences for the health and well-being of stroke survivors. To support the growing number of people who are ageing with stroke, knowledge is needed about factors that influence such activity in a long-term perspective. AIM: To identify long-term predictors of the frequency of social and leisure activities 10 years afte

Strong and independent associations between plasma concentration of cystatin C and risk of cardiovascular disease (CVD) suggests causal involvement of cystatin C.

Spruce chips steam-pretreated at various conditions, according to a central composite design, were used for investigating the influence of pretreatment conditions on enzymatic hydrolysis, accounting for the individual effects of pretreatment temperature (194-220°C), time (3-11min) and sulfur dioxide uptake (0.7-2.5%). The materials were analyzed for several surface characteristics, including IR ab

A mathematical model, based on branching processes, is proposed to interpret BrdUrd DNA FCM-derived data. Our main interest is in determining the distribution of the G2 phase duration. Two different model classes involving different assumptions on the distribution of the G2 phase duration are considered. Different assumptions of the G2 phase duration result in very similar distributions of the S p

An article about city fires.