The intestine and the brain are connected via the brain-gut axis and the intestinal microbiota influences the immune activation and signaling molecules that are involved in the stress response. The aim of the study was to investigate if intake of the probiotic strain Lactiplantibacillus plantarum HEAL9 (LPHEAL9) for four weeks could counteract elevated cortisol and inflammation levels in subjects

Evacuation models generally tend to make over-simplifications in the representation of human behaviour in fire due to the difficulties to capture its complexity. This work shows how ‘new’ discrete choice model approaches allow overcoming this issue. A description of the existing state-of-the-art of discrete choice models is introduced to highlight the potential of those models. Three case studies

The first stages of planet formation take place in protoplanetary disks that are largely made up of gas. Understanding how the gas affects planetesimals in the protoplanetary disk is therefore essential. In this paper, we discuss whether or not gas flow can erode planetesimals. We estimated how much shear stress is exerted onto the planetesimal surface by the gas as a function of disk and planetes

Rapid deforestation is a major sustainability challenge, partly as the loss of carbon sinks exacerbates global climate change. In Cambodia, more than 13% of the total land area has been contracted out to foreign and domestic agribusinesses in the form of economic land concessions, causing rapid large-scale land use change and deforestation. Additionally, the distant drivers of local and global env

Objectives To examine the under-reporting of pharmaceutical company payments to patient organisations by donors and recipients. Design Comparative descriptive analysis of payments disclosed on drug company and charity regulator websites. Setting UK. Participants 87 donors (drug companies) and 425 recipients (patient organisations) reporting payments in 2012-2016. Main outcome measures. Number and

Allogeneic hematopoietic cell transplantation is an established treatment for hematologic and other malignancies. Donor-derived immune cells can identify and attack host tumor cells, producing a graft-versus-tumor (GVT) effect that is crucial to the treatment. Using multiple tumor models and diverse donor-host combinations, we have studied the role of granzyme B (GzmB) in GVT effect. We first conf

The presence of paralytic shellfish poisoning toxins (PSTs) in drinking water resources has urged the development of simple and fast screening tools for drinking water surveillance. This article aims to validatea quick test kit for freshwater PSTs detection. Preliminary estimates of the limit of detection (LODs)were done for 5 PSPs variants, namely C1 toxin (a “C” toxin); GTX5(a Gonyautoxin); and

Abstrakt. Gradientval av överföringar gör det möjligt att förenkla polarisationsöverföringssekvenser genom att utelämna kemiska skift-återfokuseringspulser. Funktionerna hos en förenklad STEM-sekvens med tre pulser för {1H-13C} polarisationsöverföring har studerats vid 2 Tesla på ett helkropps MR-system med avseende på användning av MR-spektroskopi in vivo. Den observerade signalen ökas genom nett

The number of evacuees worldwide during wildfire keep rising, year after year. Fire evacuations at the wildland-urban interfaces (WUI) pose a serious challenge to fire and emergency services and are a global issue affecting thousands of communities around the world. But to date, there is a lack of comprehensive tools able to inform, train or aid the evacuation response and the decision making in c

It has been argued that much of contemporary epistemology can be unified under Carnap’s methodology of explication, which originated in the neighboring field of philosophy of science. However, it is unclear to what extent epistemological theories that emphasize the explanatory role of knowledge fit into this picture, Kornblith’s natural kind epistemology and Williamson’s knowledge first approach b

The modern theory of the atomic nucleus results from the merging of the liquid drop model of Niels Bohr and Fritz Kalckar, and of the shell model of Marie Goeppert Meyer and Hans Jensen. The first model contributed the concepts of collective excitations. The second, those of independent-particle motion. The unification of these apparently contradictory views in terms of the particle-vibration and

Soon after the formulation of BCS theory [1], it was recognized by Bohr, Mottelson, and Pines that the existence of an energy gap in the intrinsic excitation spectrum of deformed nuclei displayed a suggestive analogy with that observed in the electronic spectra of metallic superconductors and could, like this one, be described at profit in terms of correlated pairs [2]. Their paper represented the

Within the framework of nuclear field theory (NFT), the spectrum of atomic nuclei is described in terms of collective and quasiparticle degrees of freedom, that is, of elementary modes of excitation that are directly related to experiment and of their coupling, whose strength and form factors are the basic ingredients entering in the calculations of absolute cross sections of inelastic and of one-