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Building a map of the breast cancer proteome - Strategies to increase coverage

Popular Abstract in Swedish Uppsättningen av gener i DNA, genomet, kan betraktas som drivande för konstruktionen av varje levande varelse, medan motsvarande proteiner, proteomet, är materiellt ansvariga för de flesta biologiska processer. Kort sagt, gener bestämmer vad celler ”ska kunna göra” medan proteiner definierar vad varje cell "gör" ur en funktionell synvinkel. Aktiviteten hos dessa molekylAmongst the various –omics sciences, proteomics has the highest potential for functional characterization and consequently can contribute significantly to the field of cancer research. In particular, the focus of this thesis is on breast cancer. Alas, since state-of-the-art technologies cannot meet the complexity of upper eukaryotic proteomes, a complete resolution of clinical samples is still una

Time-domain Green dyadics for temporally dispersive, bi-isotropic media

Time-domain Green dyadics for linear, homogeneous, temporally dispersive bi-isotropic media are presented. Complex time-dependent electromagnetic field is introduced. Approximation to the complex field from an electric point dipole in an unbounded bi-isotropic medium with respect to the slowly varying components (second forerunner approximation) is obtained. Numerical examples are presented. Surfa

Strategies for Computing Switching Feedback Controllers

We consider the problem of computing suboptimal feedback switching controllers for discrete dynamical systems. The paper shows how to combine convex optimization techniques with relaxed dynamic programming. We apply the method to several problems that have been considered recently in the literature. A particularly interesting example is given by a DC-DC converter. The proposed algorithm has severa

On the cavity problem for the general linear medium in Electromagnetic Theory

In this paper we study the propagation problem of a time harmonic electromagnetic field inside a cavity filled with a generic bianisotropic medium. We define the concepts of eigenfrequencies and modes of the cavity and we propose a method to prove their existence and countability. We extend, in this respect, the theory for the isotropic, homogeneous, lossless cavity.